SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		3 / 3 GLN 1  95
HIS 1 106
PRO 1 100
 None
 0.83A 1d8cA-1cnt1:
undetectable		 1d8cA-1cnt1:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		4 / 6 LEU 1 130
GLU 1 125
LEU 1  16
LEU 1 176
 None
 0.73A 1mt1D-1cnt1:
undetectable
1mt1E-1cnt1:
undetectable		 1mt1D-1cnt1:
20.15
1mt1E-1cnt1:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		3 / 3 ILE 1 109
LEU 1 112
VAL 1 116
 None
 0.16A 1mz9B-1cnt1:
undetectable		 1mz9B-1cnt1:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		4 / 4 LEU 1  34
SER 1  37
TYR 1  38
LEU 1 162
 None
 1.23A 1xz1A-1cnt1:
6.0		 1xz1A-1cnt1:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		4 / 4 LEU 1  34
SER 1  37
TYR 1  38
LEU 1 162
 None
 1.23A 1xz3A-1cnt1:
6.1		 1xz3A-1cnt1:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		4 / 8 LEU 1  73
LEU 1  16
LEU 1 176
ARG 1  13
 None
None
None
SO4  1 190 (-3.7A)
 1.02A 2xn3A-1cnt1:
0.0
2xn3B-1cnt1:
undetectable		 2xn3A-1cnt1:
18.99
2xn3B-1cnt1:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1cnt CILIARY NEUROTROPHIC
FACTOR
(Homo
sapiens) 		5 / 12 SER 1 172
VAL 1 161
LEU 1  34
LEU 1 112
VAL 1 116
 None
 0.84A 5tudA-1cnt1:
1.4		 5tudA-1cnt1:
17.57