SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cnv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 9 PHE A  35
GLY A  85
GLN A 131
TYR A 189
TRP A 265
 None
 1.01A 1e9lA-1cnvA:
19.3		 1e9lA-1cnvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		6 / 9 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.82A 1e9lA-1cnvA:
19.3		 1e9lA-1cnvA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 11 PRO A 117
ASN A  60
VAL A  58
GLY A  59
LEU A  50
 None
 1.15A 1fkpA-1cnvA:
undetectable		 1fkpA-1cnvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 GLN A 148
LEU A 159
LEU A 110
SER A 155
 None
 0.98A 1hk3A-1cnvA:
undetectable		 1hk3A-1cnvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		6 / 11 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.84A 2a3aA-1cnvA:
19.5		 2a3aA-1cnvA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 10 PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.87A 2a3bB-1cnvA:
19.5		 2a3bB-1cnvA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 10 LEU A 249
GLY A 246
LEU A 244
LEU A 283
ILE A   2
 None
 0.98A 2f8dA-1cnvA:
undetectable		 2f8dA-1cnvA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 10 LEU A 249
GLY A 246
LEU A 244
LEU A 283
ILE A   2
 None
 0.98A 2f8dB-1cnvA:
undetectable		 2f8dB-1cnvA:
23.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		6 / 9 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.52A 2uy4A-1cnvA:
31.9		 2uy4A-1cnvA:
32.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 LEU A  83
LEU A 172
ALA A 175
PHE A 181
 None
 0.87A 2vcvF-1cnvA:
0.0		 2vcvF-1cnvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 7 LEU A  83
LEU A 172
ALA A 175
PHE A 181
 None
 0.90A 2vcvG-1cnvA:
0.0		 2vcvG-1cnvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 LEU A  83
LEU A 172
ALA A 175
PHE A 181
 None
 0.82A 2vcvP-1cnvA:
0.0		 2vcvP-1cnvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 LEU A  83
LEU A 172
ALA A 175
PHE A 181
 None
 0.84A 2vcvP-1cnvA:
0.0		 2vcvP-1cnvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 10 TYR A 259
PHE A 188
LEU A 249
VAL A 248
LEU A 252
 None
 1.47A 2w98A-1cnvA:
undetectable		 2w98A-1cnvA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		8 / 11 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
ASN A 190
ALA A 233
TRP A 265
 None
 0.66A 2xtkA-1cnvA:
33.1		 2xtkA-1cnvA:
29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		6 / 10 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.43A 2xtkB-1cnvA:
33.2		 2xtkB-1cnvA:
29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 ILE A 279
ASN A  27
ASP A 270
TYR A 275
 None
 1.12A 2zw9B-1cnvA:
undetectable		 2zw9B-1cnvA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		6 / 11 TYR A  10
PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.93A 3g6mA-1cnvA:
19.6		 3g6mA-1cnvA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 6 HIS A 127
LEU A 101
ILE A 130
LEU A  48
 None
 0.99A 3kk6A-1cnvA:
0.0		 3kk6A-1cnvA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 5 PHE A  32
ILE A  30
GLY A 125
HIS A 127
 None
 1.14A 3r0lD-1cnvA:
undetectable		 3r0lD-1cnvA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 12 ILE A  33
VAL A  31
TYR A  28
THR A  25
ILE A  69
 None
 1.14A 3vrjA-1cnvA:
undetectable
3vrjC-1cnvA:
undetectable		 3vrjA-1cnvA:
21.78
3vrjC-1cnvA:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 11 PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.53A 3wqvA-1cnvA:
19.5		 3wqvA-1cnvA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 11 PHE A  35
GLY A  85
ASP A 129
TYR A 189
TRP A 265
 None
 0.54A 3wqwA-1cnvA:
19.5		 3wqwA-1cnvA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		4 / 8 PHE A  35
GLY A  85
TYR A 189
TRP A 265
 None
 0.49A 5gqbA-1cnvA:
9.8		 5gqbA-1cnvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		3 / 3 LEU A 118
LEU A  81
ARG A  44
 None
 0.66A 5hnzB-1cnvA:
undetectable		 5hnzB-1cnvA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 12 LEU A 226
LEU A 264
ALA A 263
ILE A 204
LEU A 249
 None
 0.96A 5toaA-1cnvA:
undetectable		 5toaA-1cnvA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 1cnv CONCANAVALIN B
(Canavalia
ensiformis) 		5 / 12 ARG A 187
VAL A 186
ILE A 184
TRP A 139
ILE A 176
 None
 1.30A 6gsdA-1cnvA:
undetectable		 6gsdA-1cnvA:
12.98