SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1col'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1col COLICIN A
(Escherichia
coli) 		4 / 6 ALA A 162
SER A 102
LEU A 179
TRP A  86
 None
 1.11A 1gahA-1colA:
undetectable		 1gahA-1colA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1col COLICIN A
(Escherichia
coli) 		4 / 8 ARG A  54
SER A  62
ASP A 193
ALA A 185
 None
 1.26A 2rk8A-1colA:
2.0		 2rk8A-1colA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 1col COLICIN A
(Escherichia
coli) 		5 / 10 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.24A 3lxiA-1colA:
0.1		 3lxiA-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1col COLICIN A
(Escherichia
coli) 		5 / 11 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.24A 3lxiB-1colA:
0.0		 3lxiB-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1col COLICIN A
(Escherichia
coli) 		5 / 8 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.25A 4c9nA-1colA:
0.1		 4c9nA-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 1col COLICIN A
(Escherichia
coli) 		5 / 9 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.23A 4c9pA-1colA:
0.0		 4c9pA-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 1col COLICIN A
(Escherichia
coli) 		5 / 10 TYR A 125
LEU A 178
LEU A 179
GLY A 176
VAL A 167
 None
 1.23A 4c9pB-1colA:
0.0		 4c9pB-1colA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1col COLICIN A
(Escherichia
coli) 		3 / 3 GLY A 184
VAL A 137
MET A 134
 None
 0.62A 5ycpA-1colA:
0.0		 5ycpA-1colA:
24.64