SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1coo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 1coo RNA POLYMERASE ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 SER A 266
ARG A 284
LEU A 289
GLU A 273
 None
 1.05A 2cdqB-1cooA:
undetectable		 2cdqB-1cooA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1coo RNA POLYMERASE ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 8 ASP A 258
ASN A 268
ALA A 267
GLU A 261
 None
 0.92A 4zbqA-1cooA:
undetectable		 4zbqA-1cooA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 1coo RNA POLYMERASE ALPHA
SUBUNIT
(Escherichia
coli) 		3 / 3 TRP A 321
ILE A 326
SER A 325
 None
 1.00A 5gqbA-1cooA:
undetectable		 5gqbA-1cooA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 1coo RNA POLYMERASE ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 ASP A 258
ASN A 268
ALA A 267
GLU A 261
 None
 0.94A 6ci6A-1cooA:
undetectable		 6ci6A-1cooA:
19.80