SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cot'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1cot CYTOCHROME C2
(Paracoccus
denitrificans) 		5 / 11 ALA A  48
HIS A  19
GLY A  36
GLY A  56
ILE A  59
 HEM  A 130 (-4.6A)
HEM  A 130 (-3.1A)
HEM  A 130 ( 3.8A)
HEM  A 130 (-3.6A)
HEM  A 130 (-4.1A)
 1.14A 2x1lC-1cotA:
undetectable		 2x1lC-1cotA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1cot CYTOCHROME C2
(Paracoccus
denitrificans) 		3 / 3 TYR A  55
ARG A  45
SER A  49
 HEM  A 130 (-4.5A)
HEM  A 130 (-4.0A)
None
 0.89A 4dr2I-1cotA:
undetectable
4dr2J-1cotA:
undetectable		 4dr2I-1cotA:
23.61
4dr2J-1cotA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1cot CYTOCHROME C2
(Paracoccus
denitrificans) 		3 / 3 TYR A  55
ARG A  45
SER A  49
 HEM  A 130 (-4.5A)
HEM  A 130 (-4.0A)
None
 0.79A 4khpI-1cotA:
0.0
4khpJ-1cotA:
0.0		 4khpI-1cotA:
22.14
4khpJ-1cotA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1cot CYTOCHROME C2
(Paracoccus
denitrificans) 		3 / 3 TYR A  55
ARG A  45
SER A  49
 HEM  A 130 (-4.5A)
HEM  A 130 (-4.0A)
None
 0.75A 4lf7I-1cotA:
0.0
4lf7J-1cotA:
undetectable		 4lf7I-1cotA:
23.61
4lf7J-1cotA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1cot CYTOCHROME C2
(Paracoccus
denitrificans) 		3 / 3 TYR A  55
ARG A  45
SER A  49
 HEM  A 130 (-4.5A)
HEM  A 130 (-4.0A)
None
 0.75A 4lf8I-1cotA:
0.0
4lf8J-1cotA:
undetectable		 4lf8I-1cotA:
23.61
4lf8J-1cotA:
17.97