SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		5 / 12 PHE 3  85
PRO 3  86
PHE 3 189
PRO 3 137
ILE 3 171
 None
 1.47A 1fm4A-1cov3:
0.0		 1fm4A-1cov3:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		3 / 3 ASP 3  50
ILE 3 168
VAL 3  94
 None
 0.70A 2avvD-1cov3:
0.0		 2avvD-1cov3:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		3 / 3 LYS 3 226
GLY 3  90
PRO 3  89
 None
 0.74A 2hreB-1cov3:
0.0		 2hreB-1cov3:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 5 PHE 3  95
PHE 3  85
PHE 3  83
VAL 3 214
 None
 1.05A 2lh6A-1cov3:
undetectable		 2lh6A-1cov3:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 7 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.70A 2tsrA-1cov3:
0.0		 2tsrA-1cov3:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 8 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.85A 2tsrB-1cov3:
undetectable		 2tsrB-1cov3:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 8 ILE 3 190
GLY 3  84
PHE 3  85
SER 3  51
 None
 0.85A 4acbB-1cov3:
undetectable
4acbC-1cov3:
undetectable		 4acbB-1cov3:
18.47
4acbC-1cov3:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 7 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.78A 4iqqA-1cov3:
undetectable		 4iqqA-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 7 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.79A 4iqqC-1cov3:
undetectable		 4iqqC-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 8 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.69A 4iqqD-1cov3:
undetectable		 4iqqD-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		5 / 12 LEU 3 104
GLY 3  90
ILE 3 114
GLN 3  88
LEU 3  87
 None
 1.28A 4o5fA-1cov3:
undetectable
4o5fB-1cov3:
undetectable		 4o5fA-1cov3:
19.44
4o5fB-1cov3:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		5 / 11 GLY 3 187
GLY 3 188
GLY 3 112
ILE 3 168
PHE 3  95
 None
 1.02A 4qoiA-1cov3:
undetectable
4qoiB-1cov3:
undetectable		 4qoiA-1cov3:
24.54
4qoiB-1cov3:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		5 / 12 GLN 3  88
LEU 3  87
LEU 3 104
GLY 3  90
ILE 3 114
 None
 1.26A 5b8hA-1cov3:
undetectable
5b8hB-1cov3:
undetectable		 5b8hA-1cov3:
21.11
5b8hB-1cov3:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 7 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.72A 5nooA-1cov3:
undetectable		 5nooA-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 7 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.69A 5nooB-1cov3:
0.0		 5nooB-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		4 / 8 ILE 3 114
LEU 3 104
GLY 3 101
PHE 3  95
 None
 0.66A 5nooD-1cov3:
undetectable		 5nooD-1cov3:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1cov COXSACKIEVIRUS COAT
PROTEIN
(Enterovirus
B) 		5 / 11 LEU 3 166
VAL 3 155
ARG 3 145
ALA 3 133
GLN 3 195
 None
 1.06A 5o96A-1cov3:
undetectable
5o96B-1cov3:
undetectable		 5o96A-1cov3:
20.68
5o96B-1cov3:
20.68