SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1coy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.09A	1dfoA-1coyA: undetectable	1dfoA-1coyA: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.09A	1dfoB-1coyA: undetectable	1dfoB-1coyA: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.09A	1dfoC-1coyA: undetectable	1dfoC-1coyA: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.09A	1dfoD-1coyA: undetectable	1dfoD-1coyA: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.11A	1eqbA-1coyA: undetectable	1eqbA-1coyA: 22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.11A	1eqbB-1coyA: undetectable	1eqbB-1coyA: 22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.11A	1eqbC-1coyA: undetectable	1eqbC-1coyA: 22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 298 LEU A 307 VAL A 253 ALA A 457 PHE A 286	None	1.11A	1eqbD-1coyA: undetectable	1eqbD-1coyA: 22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FE2_A_LAXA700_2 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 453 PHE A 388 GLY A 315 SER A 295 GLY A 293	None None None None FAD A 510 ( 4.3A)	0.97A	1fe2A-1coyA: 0.0	1fe2A-1coyA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IGX_A_EPAA700_1 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	LEU A 453 PHE A 388 GLY A 315 SER A 295 GLY A 293	None None None None FAD A 510 ( 4.3A)	1.08A	1igxA-1coyA: 0.0	1igxA-1coyA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 480 VAL A 482 ALA A 386 GLY A 475 SER A 291	None None None FAD A 510 (-3.6A) None	1.11A	1kiaA-1coyA: undetectable	1kiaA-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.09A	1kiaA-1coyA: undetectable	1kiaA-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.07A	1kiaD-1coyA: 2.2	1kiaD-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA442_1 (ALPHA AMYLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 11	GLY A 212 PHE A 197 GLY A 224 GLY A 120 GLY A 121	None None None AND A 508 ( 3.1A) FAD A 510 (-4.1A)	1.08A	1mxgA-1coyA: undetectable	1mxgA-1coyA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBH_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.11A	1nbhA-1coyA: 2.1	1nbhA-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBH_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.12A	1nbhC-1coyA: undetectable	1nbhC-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBH_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.09A	1nbhD-1coyA: undetectable	1nbhD-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 480 VAL A 482 ALA A 386 GLY A 475 SER A 291	None None None FAD A 510 (-3.6A) None	1.13A	1nbiA-1coyA: undetectable	1nbiA-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.06A	1nbiA-1coyA: undetectable	1nbiA-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 480 VAL A 482 ALA A 386 GLY A 475 SER A 291	None None None FAD A 510 (-3.6A) None	1.11A	1nbiB-1coyA: 2.5	1nbiB-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 21 GLY A 114 VAL A 95 ALA A 24 SER A 227	FAD A 510 (-4.4A) FAD A 510 (-3.0A) None None None	1.08A	1nbiB-1coyA: 2.5	1nbiB-1coyA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PN0_A_IPHA6012_0 (PHENOL 2-MONOOXYGENASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	GLY A 290 GLN A 108 ARG A 110 MET A 42 GLY A 293	FAD A 510 (-3.5A) None FAD A 510 (-4.3A) FAD A 510 (-3.7A) FAD A 510 ( 4.3A)	1.08A	1pn0A-1coyA: 13.4	1pn0A-1coyA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PN0_B_IPHB6022_0 (PHENOL 2-MONOOXYGENASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	GLY A 290 GLN A 108 ARG A 110 MET A 42 GLY A 293	FAD A 510 (-3.5A) None FAD A 510 (-4.3A) FAD A 510 (-3.7A) FAD A 510 ( 4.3A)	1.07A	1pn0B-1coyA: 14.1	1pn0B-1coyA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_C_NCAC339_0 (ADP-RIBOSYL CYCLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	3 / 3	GLU A 384 ASN A 382 TRP A 401	None	0.83A	1r15C-1coyA: undetectable	1r15C-1coyA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_D_NCAD349_0 (ADP-RIBOSYL CYCLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	3 / 3	GLU A 384 ASN A 382 TRP A 401	None	0.79A	1r15D-1coyA: undetectable	1r15D-1coyA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_E_NCAE359_0 (ADP-RIBOSYL CYCLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	3 / 3	GLU A 384 ASN A 382 TRP A 401	None	0.82A	1r15E-1coyA: undetectable	1r15E-1coyA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_F_NCAF369_0 (ADP-RIBOSYL CYCLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	3 / 3	GLU A 384 ASN A 382 TRP A 401	None	0.80A	1r15F-1coyA: undetectable	1r15F-1coyA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	VAL A 314 GLY A 315 VAL A 452 TRP A 318	None	0.92A	1tkqB-1coyA: undetectable	1tkqB-1coyA: 3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O5Y_H_STRH249_1 (CHIMERIC ANTIBODY FAB 1E9-DB3)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 7	ASN A 497 GLY A 462 THR A 458 SER A 137	None	1.07A	2o5yH-1coyA: undetectable 2o5yL-1coyA: undetectable	2o5yH-1coyA: 18.42 2o5yL-1coyA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_A_SAMA300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 293 GLY A 23 GLY A 18 ASP A 474 VAL A 473	FAD A 510 ( 4.3A) None FAD A 510 (-3.2A) FAD A 510 (-4.7A) None	0.95A	2oxtA-1coyA: undetectable	2oxtA-1coyA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_D_SAMD603_0 (HYPOTHETICAL PROTEIN)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 22 GLY A 20 ALA A 27 ASP A 474 VAL A 473	FAD A 510 (-3.9A) FAD A 510 (-3.4A) None FAD A 510 (-4.7A) None	1.19A	2yvlD-1coyA: 3.1	2yvlD-1coyA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_B_SAMB402_0 (UNCHARACTERIZED PROTEIN MJ0883)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	TYR A 219 GLY A 220 ILE A 55 ASN A 222 ASP A 47	None	1.46A	2zznB-1coyA: 2.3	2zznB-1coyA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELW_A_SAMA4633_0 (METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	GLY A 20 GLY A 475 GLY A 22 ASN A 481 VAL A 482	FAD A 510 (-3.4A) FAD A 510 (-3.6A) FAD A 510 (-3.9A) None None	0.82A	3elwA-1coyA: undetectable	3elwA-1coyA: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM6_A_017A200_1 (PROTEASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 8	GLY A 224 ALA A 223 GLY A 214 LEU A 213	None	0.61A	3em6A-1coyA: undetectable	3em6A-1coyA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_B_ECLB600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 8	LEU A 493 GLY A 23 ALA A 26 ILE A 501	None	0.83A	3jusB-1coyA: 0.0	3jusB-1coyA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_0 (SAM-DEPENDENT METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	VAL A 191 GLY A 121 ALA A 123 ILE A 218 PRO A 364	None FAD A 510 (-4.1A) None FAD A 510 ( 4.6A) AND A 508 ( 4.6A)	0.96A	3mb5A-1coyA: 3.2	3mb5A-1coyA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U6T_A_KANA4699_1 (RIBOSOME INACTIVATING PROTEIN)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	ILE A 490 SER A 116 TYR A 232 ALA A 494 GLU A 495	FAD A 510 ( 4.3A) None None None None	1.46A	3u6tA-1coyA: undetectable	3u6tA-1coyA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EY7_A_E20A604_1 (ACETYLCHOLINESTERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 11	TYR A 107 TRP A 68 GLY A 109 GLU A 41 GLY A 43	None None None FAD A 510 (-2.7A) None	1.46A	4ey7A-1coyA: undetectable	4ey7A-1coyA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	GLY A 114 GLY A 115 ASN A 119 GLU A 41	FAD A 510 (-3.0A) FAD A 510 (-3.4A) FAD A 510 (-4.1A) FAD A 510 (-2.7A)	1.29A	4fglC-1coyA: 2.8	4fglC-1coyA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	GLY A 214 GLY A 215 MET A 59 GLU A 203	None None AND A 508 ( 4.0A) None	1.21A	4fglC-1coyA: 2.8	4fglC-1coyA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K87_A_ADNA602_1 (PROLINE--TRNA LIGASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 8	PHE A 165 GLN A 340 GLY A 337 THR A 336	None	0.97A	4k87A-1coyA: 2.5	4k87A-1coyA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LBG_B_ADNB402_1 (PROBABLE SUGAR KINASE PROTEIN)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 9	ALA A 237 ILE A 244 VAL A 112 ALA A 24 ALA A 27	None	1.04A	4lbgB-1coyA: undetectable	4lbgB-1coyA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PO0_A_NPSA603_1 (SERUM ALBUMIN)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	LEU A 233 LEU A 242 VAL A 40 LEU A 6 LEU A 15	None	1.19A	4po0A-1coyA: undetectable	4po0A-1coyA: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QRC_A_0LIA802_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	ALA A 27 LEU A 298 ALA A 288 ASP A 474 LEU A 477	None None None FAD A 510 (-4.7A) None	1.11A	4qrcA-1coyA: undetectable	4qrcA-1coyA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RJD_B_TFPB204_1 (CALMODULIN)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 8	GLY A 215 GLU A 216 GLU A 203 ALA A 204	None	0.81A	4rjdA-1coyA: 0.4 4rjdB-1coyA: 0.0	4rjdA-1coyA: 7.69 4rjdB-1coyA: 7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUC_A_SAMA303_1 (CATECHOL O-METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 4	SER A 102 GLU A 99 SER A 295 ASP A 398	None	1.47A	4xucA-1coyA: 0.0	4xucA-1coyA: 17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HV1_A_RFPA902_1 (PHOSPHOENOLPYRUVATE SYNTHASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	ALA A 282 VAL A 263 LEU A 307 LEU A 30 ILE A 501	None	1.11A	5hv1A-1coyA: 0.0	5hv1A-1coyA: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGI_A_ZITA402_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	ILE A 39 ALA A 494 MET A 498 GLY A 462 THR A 458	None	1.27A	5igiA-1coyA: 0.0	5igiA-1coyA: 21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LBT_A_6T0A304_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	GLY A 214 GLY A 215 MET A 59 GLU A 203 ILE A 343	None None AND A 508 ( 4.0A) None None	1.43A	5lbtA-1coyA: 3.0 5lbtB-1coyA: 2.9	5lbtA-1coyA: 17.67 5lbtB-1coyA: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YOD_B_BEZB201_0 (NS3 PROTEASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	ALA A 223 SER A 211 GLY A 212 TYR A 195	None	1.28A	5yodB-1coyA: undetectable	5yodB-1coyA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YOD_D_BEZD201_0 (NS3 PROTEASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	ALA A 223 SER A 211 GLY A 212 TYR A 195	None	1.19A	5yodD-1coyA: undetectable	5yodD-1coyA: 17.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.09A","1dfoA-1coyA:undetectable","1dfoA-1coyA:22.53"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.09A","1dfoB-1coyA:undetectable","1dfoB-1coyA:22.53"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.09A","1dfoC-1coyA:undetectable","1dfoC-1coyA:22.53"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.09A","1dfoD-1coyA:undetectable","1dfoD-1coyA:22.53"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.11A","1eqbA-1coyA:undetectable","1eqbA-1coyA:22.57"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.11A","1eqbB-1coyA:undetectable","1eqbB-1coyA:22.57"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.11A","1eqbC-1coyA:undetectable","1eqbC-1coyA:22.57"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 298;LEU A 307;VAL A 253;ALA A 457;PHE A 286","None","1.11A","1eqbD-1coyA:undetectable","1eqbD-1coyA:22.57"],["1FE2_A_LAXA700_2","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 453;PHE A 388;GLY A 315;SER A 295;GLY A 293","None;None;None;None;FAD A 510 ( 4.3A)","0.97A","1fe2A-1coyA:0.0","1fe2A-1coyA:23.32"],["1IGX_A_EPAA700_1","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 453;PHE A 388;GLY A 315;SER A 295;GLY A 293","None;None;None;None;FAD A 510 ( 4.3A)","1.08A","1igxA-1coyA:0.0","1igxA-1coyA:23.32"],["1KIA_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 480;VAL A 482;ALA A 386;GLY A 475;SER A 291","None;None;None;FAD A 510 (-3.6A);None","1.11A","1kiaA-1coyA:undetectable","1kiaA-1coyA:22.22"],["1KIA_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.09A","1kiaA-1coyA:undetectable","1kiaA-1coyA:22.22"],["1KIA_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.07A","1kiaD-1coyA:2.2","1kiaD-1coyA:22.22"],["1MXG_A_ACRA442_1","ALPHA AMYLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 212;PHE A 197;GLY A 224;GLY A 120;GLY A 121","None;None;None;AND A 508 ( 3.1A);FAD A 510 (-4.1A)","1.08A","1mxgA-1coyA:undetectable","1mxgA-1coyA:23.24"],["1NBH_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.11A","1nbhA-1coyA:2.1","1nbhA-1coyA:22.22"],["1NBH_C_SAMC2293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.12A","1nbhC-1coyA:undetectable","1nbhC-1coyA:22.22"],["1NBH_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.09A","1nbhD-1coyA:undetectable","1nbhD-1coyA:22.22"],["1NBI_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 480;VAL A 482;ALA A 386;GLY A 475;SER A 291","None;None;None;FAD A 510 (-3.6A);None","1.13A","1nbiA-1coyA:undetectable","1nbiA-1coyA:22.22"],["1NBI_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.06A","1nbiA-1coyA:undetectable","1nbiA-1coyA:22.22"],["1NBI_B_SAMB1293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 480;VAL A 482;ALA A 386;GLY A 475;SER A 291","None;None;None;FAD A 510 (-3.6A);None","1.11A","1nbiB-1coyA:2.5","1nbiB-1coyA:22.22"],["1NBI_B_SAMB1293_0","GLYCINE N-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A  21;GLY A 114;VAL A  95;ALA A  24;SER A 227","FAD A 510 (-4.4A);FAD A 510 (-3.0A);None;None;None","1.08A","1nbiB-1coyA:2.5","1nbiB-1coyA:22.22"],["1PN0_A_IPHA6012_0","PHENOL 2-MONOOXYGENASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 290;GLN A 108;ARG A 110;MET A  42;GLY A 293","FAD A 510 (-3.5A);None;FAD A 510 (-4.3A);FAD A 510 (-3.7A);FAD A 510 ( 4.3A)","1.08A","1pn0A-1coyA:13.4","1pn0A-1coyA:22.70"],["1PN0_B_IPHB6022_0","PHENOL 2-MONOOXYGENASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 290;GLN A 108;ARG A 110;MET A  42;GLY A 293","FAD A 510 (-3.5A);None;FAD A 510 (-4.3A);FAD A 510 (-3.7A);FAD A 510 ( 4.3A)","1.07A","1pn0B-1coyA:14.1","1pn0B-1coyA:22.70"],["1R15_C_NCAC339_0","ADP-RIBOSYL CYCLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",3,"GLU A 384;ASN A 382;TRP A 401","None","0.83A","1r15C-1coyA:undetectable","1r15C-1coyA:19.57"],["1R15_D_NCAD349_0","ADP-RIBOSYL CYCLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",3,"GLU A 384;ASN A 382;TRP A 401","None","0.79A","1r15D-1coyA:undetectable","1r15D-1coyA:19.57"],["1R15_E_NCAE359_0","ADP-RIBOSYL CYCLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",3,"GLU A 384;ASN A 382;TRP A 401","None","0.82A","1r15E-1coyA:undetectable","1r15E-1coyA:19.57"],["1R15_F_NCAF369_0","ADP-RIBOSYL CYCLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",3,"GLU A 384;ASN A 382;TRP A 401","None","0.80A","1r15F-1coyA:undetectable","1r15F-1coyA:19.57"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"VAL A 314;GLY A 315;VAL A 452;TRP A 318","None","0.92A","1tkqB-1coyA:undetectable","1tkqB-1coyA:3.03"],["2O5Y_H_STRH249_1","CHIMERIC ANTIBODY FAB 1E9-DB3;CHIMERIC ANTIBODY FAB 1E9-DB3","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"ASN A 497;GLY A 462;THR A 458;SER A 137","None","1.07A","2o5yH-1coyA:undetectable;2o5yL-1coyA:undetectable","2o5yH-1coyA:18.42;2o5yL-1coyA:21.18"],["2OXT_A_SAMA300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 293;GLY A  23;GLY A  18;ASP A 474;VAL A 473","FAD A 510 ( 4.3A);None;FAD A 510 (-3.2A);FAD A 510 (-4.7A);None","0.95A","2oxtA-1coyA:undetectable","2oxtA-1coyA:20.28"],["2YVL_D_SAMD603_0","HYPOTHETICAL PROTEIN","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A  22;GLY A  20;ALA A  27;ASP A 474;VAL A 473","FAD A 510 (-3.9A);FAD A 510 (-3.4A);None;FAD A 510 (-4.7A);None","1.19A","2yvlD-1coyA:3.1","2yvlD-1coyA:20.40"],["2ZZN_B_SAMB402_0","UNCHARACTERIZED PROTEIN MJ0883","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A 219;GLY A 220;ILE A  55;ASN A 222;ASP A  47","None","1.46A","2zznB-1coyA:2.3","2zznB-1coyA:19.45"],["3ELW_A_SAMA4633_0","METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A  20;GLY A 475;GLY A  22;ASN A 481;VAL A 482","FAD A 510 (-3.4A);FAD A 510 (-3.6A);FAD A 510 (-3.9A);None;None","0.82A","3elwA-1coyA:undetectable","3elwA-1coyA:19.76"],["3EM6_A_017A200_1","PROTEASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"GLY A 224;ALA A 223;GLY A 214;LEU A 213","None","0.61A","3em6A-1coyA:undetectable","3em6A-1coyA:12.61"],["3JUS_B_ECLB600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"LEU A 493;GLY A  23;ALA A  26;ILE A 501","None","0.83A","3jusB-1coyA:0.0","3jusB-1coyA:20.07"],["3MB5_A_SAMA301_0","SAM-DEPENDENT METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"VAL A 191;GLY A 121;ALA A 123;ILE A 218;PRO A 364","None;FAD A 510 (-4.1A);None;FAD A 510 ( 4.6A);AND A 508 ( 4.6A)","0.96A","3mb5A-1coyA:3.2","3mb5A-1coyA:18.79"],["3U6T_A_KANA4699_1","RIBOSOME INACTIVATING PROTEIN","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"ILE A 490;SER A 116;TYR A 232;ALA A 494;GLU A 495","FAD A 510 ( 4.3A);None;None;None;None","1.46A","3u6tA-1coyA:undetectable","3u6tA-1coyA:21.07"],["4EY7_A_E20A604_1","ACETYLCHOLINESTERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"TYR A 107;TRP A  68;GLY A 109;GLU A  41;GLY A  43","None;None;None;FAD A 510 (-2.7A);None","1.46A","4ey7A-1coyA:undetectable","4ey7A-1coyA:21.58"],["4FGL_C_CLQC303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"GLY A 114;GLY A 115;ASN A 119;GLU A  41","FAD A 510 (-3.0A);FAD A 510 (-3.4A);FAD A 510 (-4.1A);FAD A 510 (-2.7A)","1.29A","4fglC-1coyA:2.8","4fglC-1coyA:19.07"],["4FGL_C_CLQC303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"GLY A 214;GLY A 215;MET A  59;GLU A 203","None;None;AND A 508 ( 4.0A);None","1.21A","4fglC-1coyA:2.8","4fglC-1coyA:19.07"],["4K87_A_ADNA602_1","PROLINE--TRNA LIGASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"PHE A 165;GLN A 340;GLY A 337;THR A 336","None","0.97A","4k87A-1coyA:2.5","4k87A-1coyA:23.21"],["4LBG_B_ADNB402_1","PROBABLE SUGAR KINASE PROTEIN","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"ALA A 237;ILE A 244;VAL A 112;ALA A  24;ALA A  27","None","1.04A","4lbgB-1coyA:undetectable","4lbgB-1coyA:21.58"],["4PO0_A_NPSA603_1","SERUM ALBUMIN","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"LEU A 233;LEU A 242;VAL A  40;LEU A   6;LEU A  15","None","1.19A","4po0A-1coyA:undetectable","4po0A-1coyA:19.87"],["4QRC_A_0LIA802_1","FIBROBLAST GROWTH FACTOR RECEPTOR 4","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"ALA A  27;LEU A 298;ALA A 288;ASP A 474;LEU A 477","None;None;None;FAD A 510 (-4.7A);None","1.11A","4qrcA-1coyA:undetectable","4qrcA-1coyA:18.67"],["4RJD_B_TFPB204_1","CALMODULIN;CALMODULIN","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"GLY A 215;GLU A 216;GLU A 203;ALA A 204","None","0.81A","4rjdA-1coyA:0.4;4rjdB-1coyA:0.0","4rjdA-1coyA:7.69;4rjdB-1coyA:7.69"],["4XUC_A_SAMA303_1","CATECHOL O-METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"SER A 102;GLU A  99;SER A 295;ASP A 398","None","1.47A","4xucA-1coyA:0.0","4xucA-1coyA:17.38"],["5HV1_A_RFPA902_1","PHOSPHOENOLPYRUVATE SYNTHASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"ALA A 282;VAL A 263;LEU A 307;LEU A  30;ILE A 501","None","1.11A","5hv1A-1coyA:0.0","5hv1A-1coyA:21.91"],["5IGI_A_ZITA402_1","MACROLIDE 2'-PHOSPHOTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"ILE A  39;ALA A 494;MET A 498;GLY A 462;THR A 458","None","1.27A","5igiA-1coyA:0.0","5igiA-1coyA:21.79"],["5LBT_A_6T0A304_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 214;GLY A 215;MET A  59;GLU A 203;ILE A 343","None;None;AND A 508 ( 4.0A);None;None","1.43A","5lbtA-1coyA:3.0;5lbtB-1coyA:2.9","5lbtA-1coyA:17.67;5lbtB-1coyA:17.67"],["5YOD_B_BEZB201_0","NS3 PROTEASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"ALA A 223;SER A 211;GLY A 212;TYR A 195","None","1.28A","5yodB-1coyA:undetectable","5yodB-1coyA:17.36"],["5YOD_D_BEZD201_0","NS3 PROTEASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"ALA A 223;SER A 211;GLY A 212;TYR A 195","None","1.19A","5yodD-1coyA:undetectable","5yodD-1coyA:17.36"]]