SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 8 GLY A 164
ALA A 169
ILE A 165
SER A 171
 None
 0.81A 1gtnP-1cp2A:
0.0
1gtnQ-1cp2A:
0.0		 1gtnP-1cp2A:
14.48
1gtnQ-1cp2A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 7 ASP A  38
ALA A  41
ILE A  12
THR A  18
 None
 0.78A 1t7jB-1cp2A:
undetectable		 1t7jB-1cp2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 5 GLY A 125
PRO A 135
ALA A 141
ILE A 144
 None
 0.91A 2aofA-1cp2A:
undetectable		 2aofA-1cp2A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		3 / 3 LYS A  14
ASP A  58
ASP A  38
 None
 0.69A 2br4D-1cp2A:
undetectable		 2br4D-1cp2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 12 TYR A 121
ALA A 133
ALA A 141
GLY A  96
GLY A 130
 None
 1.12A 2igtA-1cp2A:
3.4		 2igtA-1cp2A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 12 TYR A 121
ALA A 133
ALA A 141
GLY A  96
GLY A 130
 None
 1.11A 2igtB-1cp2A:
undetectable		 2igtB-1cp2A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 6 ARG A  61
SER A 102
SER A  55
GLY A  86
 None
 0.96A 2j2pA-1cp2A:
undetectable
2j2pC-1cp2A:
undetectable		 2j2pA-1cp2A:
22.30
2j2pC-1cp2A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 6 ARG A  61
SER A 102
SER A  55
GLY A  86
 None
 1.00A 2j2pD-1cp2A:
0.0
2j2pF-1cp2A:
undetectable		 2j2pD-1cp2A:
22.30
2j2pF-1cp2A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 8 PHE A 120
ILE A   6
GLY A 177
ILE A 179
 None
 0.98A 2qwxA-1cp2A:
6.0
2qwxB-1cp2A:
5.9		 2qwxA-1cp2A:
22.65
2qwxB-1cp2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 7 TYR A 121
VAL A 123
TYR A   7
ILE A 136
 None
 1.20A 2x45B-1cp2A:
0.0		 2x45B-1cp2A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 7 TYR A 121
VAL A 123
TYR A   7
ILE A 136
 None
 1.19A 2x45C-1cp2A:
0.0		 2x45C-1cp2A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 7 TYR A 121
VAL A 123
TYR A   7
ILE A 136
 None
 1.13A 3bu1A-1cp2A:
undetectable		 3bu1A-1cp2A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		6 / 11 ASP A  38
ALA A  41
ASP A  42
GLY A  13
ILE A  12
THR A  18
 None
 1.29A 3ekxA-1cp2A:
undetectable		 3ekxA-1cp2A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		6 / 12 ASP A  38
ALA A  41
ASP A  42
GLY A  13
ILE A  12
THR A  18
 None
 1.18A 3el5B-1cp2A:
undetectable		 3el5B-1cp2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 8 ASP A  38
ALA A  41
ILE A  12
THR A  18
 None
 0.85A 3el9A-1cp2A:
undetectable		 3el9A-1cp2A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 12 LEU A 193
PHE A 196
ILE A   6
ALA A   5
GLY A 177
 None
 1.07A 3nxuA-1cp2A:
undetectable		 3nxuA-1cp2A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 8 ALA A  41
ASP A  42
GLY A  13
ILE A  12
THR A  18
 None
 1.24A 3so9A-1cp2A:
0.0		 3so9A-1cp2A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 11 ASP A  38
ALA A  41
GLY A  13
ILE A  12
THR A  18
 None
 0.81A 3ufnA-1cp2A:
undetectable		 3ufnA-1cp2A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 10 ALA A 133
ILE A 165
ALA A   5
ALA A 141
ILE A 144
 None
 1.04A 4lbgA-1cp2A:
undetectable		 4lbgA-1cp2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 9 ALA A 133
ILE A 165
ALA A   5
ALA A 141
ILE A 144
 None
 1.08A 4lbgB-1cp2A:
3.5		 4lbgB-1cp2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 11 ASP A  38
ALA A  41
GLY A  13
ILE A  12
THR A  18
 None
 0.98A 4qgiA-1cp2A:
undetectable		 4qgiA-1cp2A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		4 / 4 ILE A 205
ARG A   2
TYR A 145
GLU A 143
 None
 1.32A 4zzbD-1cp2A:
undetectable		 4zzbD-1cp2A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1cp2 NITROGENASE IRON
PROTEIN
(Clostridium
pasteurianum) 		5 / 8 ALA A 154
LEU A 192
LEU A 193
LEU A 261
LEU A 265
 None
 1.38A 5jqbA-1cp2A:
0.0
5jqbB-1cp2A:
undetectable		 5jqbA-1cp2A:
24.20
5jqbB-1cp2A:
19.85