SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 VAL B 155
TRP B 166
TRP B  65
 None
 1.17A 1c4dA-1cp9B:
undetectable
1c4dB-1cp9B:
undetectable		 1c4dA-1cp9B:
2.63
1c4dB-1cp9B:
2.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 7 SER B   1
PHE B  24
SER B  67
ALA B  69
ILE B 177
 None
 0.59A 1fxhA-1cp9B:
0.0
1fxhB-1cp9B:
57.9		 1fxhA-1cp9B:
18.70
1fxhB-1cp9B:
64.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 7 PHE A 144
SER B   1
PHE B  24
ALA B  69
ILE B 177
 None
 0.62A 1fxhA-1cp9A:
23.4
1fxhB-1cp9A:
undetectable		 1fxhA-1cp9A:
64.25
1fxhB-1cp9A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 SER B   1
PHE B  24
ALA B  69
PHE B  71
 None
 0.32A 1fxvA-1cp9B:
0.0
1fxvB-1cp9B:
57.8		 1fxvA-1cp9B:
18.70
1fxvB-1cp9B:
64.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 8 PHE B  24
SER B  67
ALA B  69
PHE B  71
ILE B 177
 None
 0.51A 1gm7A-1cp9B:
0.0
1gm7B-1cp9B:
57.4		 1gm7A-1cp9B:
18.70
1gm7B-1cp9B:
63.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 8 SER B   1
PHE B  24
ALA B  69
PHE B  71
ILE B 177
 None
 0.23A 1gm7A-1cp9B:
0.0
1gm7B-1cp9B:
57.4		 1gm7A-1cp9B:
18.70
1gm7B-1cp9B:
63.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 SER B   1
PRO B  22
SER B  67
ALA B  69
 None
 0.89A 1k5qA-1cp9B:
0.0
1k5qB-1cp9B:
57.6		 1k5qA-1cp9B:
18.64
1k5qB-1cp9B:
64.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 SER B   1
TYR B  31
SER B  67
ALA B  69
 None
 0.84A 1k5qA-1cp9B:
0.0
1k5qB-1cp9B:
57.6		 1k5qA-1cp9B:
18.64
1k5qB-1cp9B:
64.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		3 / 3 ASP B 538
HIS A  16
ASP A  10
 None
 0.88A 1nw5A-1cp9B:
undetectable		 1nw5A-1cp9B:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		6 / 8 SER B   1
PHE B  24
SER B  67
ALA B  69
ILE B 177
ASN B 241
 None
 0.48A 1pnlA-1cp9B:
0.0
1pnlB-1cp9B:
56.5		 1pnlA-1cp9B:
18.70
1pnlB-1cp9B:
64.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		6 / 8 PHE A 144
SER B   1
PHE B  24
ALA B  69
ILE B 177
ASN B 241
 None
 0.48A 1pnlA-1cp9A:
22.8
1pnlB-1cp9A:
undetectable		 1pnlA-1cp9A:
64.25
1pnlB-1cp9A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 GLY B  66
PHE B  57
ASP B 497
THR B  32
 None
 1.11A 2aouB-1cp9B:
undetectable		 2aouB-1cp9B:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLU B 398
GLY B 259
ASP B 262
ASN A 181
ALA B 250
 None
 1.28A 2bm9B-1cp9B:
undetectable		 2bm9B-1cp9B:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 6 PHE B 460
SER A  47
GLY A 138
ARG A 143
 None
 1.00A 2f7fA-1cp9B:
undetectable		 2f7fA-1cp9B:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 TYR A  71
GLY A 138
THR A  48
ASN A 142
 None
 1.09A 2g70A-1cp9A:
undetectable		 2g70A-1cp9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 TYR A  71
GLY A 138
THR A  48
ASN A 142
 None
 1.06A 2g70B-1cp9A:
undetectable		 2g70B-1cp9A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 9 GLY B 360
LEU B 355
THR B 358
ALA B 357
THR B 426
 None
 1.09A 2npnA-1cp9B:
undetectable		 2npnA-1cp9B:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 8 ASN A 148
ILE B  77
ASP B  76
ARG B 199
 CA  B 554 ( 4.9A)
None
CA  B 554 (-3.7A)
None
 1.10A 2v57A-1cp9A:
0.0		 2v57A-1cp9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 8 ASN A 148
ILE B  77
ASP B  76
ARG B 199
 CA  B 554 ( 4.9A)
None
CA  B 554 (-3.7A)
None
 1.10A 2v57C-1cp9A:
undetectable		 2v57C-1cp9A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 TRP B 154
GLN B 169
TRP B 143
 None
 1.28A 2vqyA-1cp9B:
0.0		 2vqyA-1cp9B:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 10 ILE A  90
PHE A  26
THR B  48
ILE B  35
LEU B  37
 None
 1.22A 2w3aB-1cp9A:
undetectable		 2w3aB-1cp9A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 6 ARG B 553
ASP A  89
ILE A  90
GLN B 159
 None
 1.35A 2ya7C-1cp9B:
undetectable		 2ya7C-1cp9B:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 PHE B 460
ASN B 458
PHE B  50
 None
 1.06A 2zbuD-1cp9B:
undetectable		 2zbuD-1cp9B:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 GLY B 158
HIS A  16
LEU A  25
HIS B  38
LEU B 534
 None
 0.84A 3cs8A-1cp9B:
0.0		 3cs8A-1cp9B:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLY B  39
ASN A  20
ASP A  21
ILE B  44
GLY B 158
 None
 1.15A 3eeyA-1cp9B:
undetectable		 3eeyA-1cp9B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLY B  39
ASN A  20
ASP A  21
ILE B  44
GLY B 158
 None
 1.16A 3eeyB-1cp9B:
undetectable		 3eeyB-1cp9B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLY B  39
ASN A  20
ASP A  21
ILE B  44
GLY B 158
 None
 1.14A 3eeyF-1cp9B:
undetectable		 3eeyF-1cp9B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLY B  39
ASN A  20
ASP A  21
ILE B  44
GLY B 158
 None
 1.17A 3eeyH-1cp9B:
undetectable		 3eeyH-1cp9B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		5 / 12 GLY B  39
ASN A  20
ASP A  21
ILE B  44
GLY B 158
 None
 1.17A 3eeyI-1cp9B:
undetectable		 3eeyI-1cp9B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		6 / 12 ASP B 484
VAL B 499
GLY B 480
THR B  32
PRO B  49
THR B  48
 None
 1.41A 3el5B-1cp9B:
undetectable		 3el5B-1cp9B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FUU_A_ADNA0_1
(DIMETHYLADENOSINE
TRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 VAL A  33
GLY A  30
GLY A  97
ALA B  51
ILE B  35
 None
 0.96A 3fuuA-1cp9A:
undetectable		 3fuuA-1cp9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 VAL A 132
MET B 152
ILE A  90
TYR A  94
 None
 1.00A 3hgxA-1cp9A:
undetectable		 3hgxA-1cp9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 GLU B 544
GLY B  36
ASP B 519
ASP B 497
GLY B 502
 None
 1.42A 3jzjA-1cp9B:
0.0		 3jzjA-1cp9B:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 LEU B 298
LEU B 400
LEU B 401
ILE B 389
LEU B 351
 None
 1.21A 3olsB-1cp9B:
undetectable		 3olsB-1cp9B:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 8 VAL A 132
VAL B 155
TYR A  94
ILE A  90
 None
 0.90A 3remA-1cp9A:
undetectable		 3remA-1cp9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 8 VAL A 132
VAL B 155
TYR A  94
ILE A  90
 None
 0.89A 3remB-1cp9A:
undetectable		 3remB-1cp9A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 PHE B  24
GLN B 464
PHE B  57
 None
 0.84A 3rv5A-1cp9B:
1.0		 3rv5A-1cp9B:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 5 ILE A 188
THR A 187
THR A 186
SER B 243
 None
 1.01A 3snfA-1cp9A:
0.0		 3snfA-1cp9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 5 ARG A 143
TYR B  31
PHE B  50
PRO B  49
 None
 1.46A 3tgvC-1cp9A:
0.0		 3tgvC-1cp9A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 PHE B 302
LYS B 404
SER B 405
 None
 1.08A 3tyeB-1cp9B:
undetectable		 3tyeB-1cp9B:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 10 ILE A  90
VAL A 132
PHE A  26
THR B  48
ILE B  35
 None
 1.29A 3um5A-1cp9A:
undetectable		 3um5A-1cp9A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 10 ILE A  90
VAL A 132
PHE A  26
THR B  48
ILE B  35
 None
 1.31A 3um5B-1cp9A:
undetectable		 3um5B-1cp9A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 6 HIS B  92
ASP B  73
ASP B 216
GLU A 150
 None
CA  B 554 (-2.2A)
None
CA  B 554 (-3.4A)
 1.33A 3vywA-1cp9B:
undetectable		 3vywA-1cp9B:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 8 PRO B 232
ILE B 188
LEU B   5
ILE B 237
 None
 0.79A 4dtaB-1cp9B:
2.3		 4dtaB-1cp9B:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 6 ARG B 479
GLY B  21
ASN B  47
GLU B 482
 None
 1.29A 4g0vB-1cp9B:
undetectable		 4g0vB-1cp9B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 5 LEU B  18
TRP B  65
ILE B  44
ASN B 535
 None
 1.44A 4i00A-1cp9B:
undetectable		 4i00A-1cp9B:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 6 THR B 481
PRO B  22
ARG A 143
PHE B  57
 None
 1.25A 4kf9A-1cp9B:
0.0		 4kf9A-1cp9B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 9 ASP A  36
VAL B 499
ALA B 500
GLY A  13
SER B 504
 None
 1.30A 4mmeA-1cp9A:
undetectable		 4mmeA-1cp9A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 9 ASP A  36
VAL B 499
ALA B 500
GLY A  13
SER B 504
 None
 1.29A 4mmeB-1cp9A:
undetectable		 4mmeB-1cp9A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 ARG B 102
TRP A  72
ILE B 118
 None
 1.01A 4mwxA-1cp9B:
undetectable		 4mwxA-1cp9B:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 GLY A  97
GLY A  93
ILE A   5
SER A  24
ALA A 100
 None
 1.13A 4qtuB-1cp9A:
undetectable		 4qtuB-1cp9A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 TRP B  65
GLY B  66
GLY B  58
ILE B  35
ASP B 484
 None
 1.21A 4rtsA-1cp9B:
0.0		 4rtsA-1cp9B:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 10 TYR A  94
ALA A  32
ILE B  35
LEU B  37
TYR B  33
 None
 1.10A 4xj7A-1cp9A:
undetectable
4xj7B-1cp9A:
undetectable		 4xj7A-1cp9A:
17.65
4xj7B-1cp9A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 5 GLY A  13
TYR B 517
SER B 504
GLU B 544
 None
 1.34A 4xueA-1cp9A:
undetectable		 4xueA-1cp9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 11 GLY A  93
ALA A  19
ILE A  17
LEU B  37
ILE A  90
 None
 1.15A 4xumB-1cp9A:
0.0		 4xumB-1cp9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		3 / 3 ASN B 315
ASP B 440
GLY B 439
 None
 0.65A 5fctB-1cp9B:
0.0		 5fctB-1cp9B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 8 ASP B 293
TYR B 339
SER B 386
ASN B 478
 None
 0.91A 5l1fA-1cp9B:
undetectable
5l1fB-1cp9B:
undetectable		 5l1fA-1cp9B:
21.11
5l1fB-1cp9B:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 ILE B 188
GLY B 189
ALA B 182
ILE B  17
ALA B  16
 None
 1.06A 5n0tB-1cp9B:
undetectable		 5n0tB-1cp9B:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		4 / 7 GLY B  58
GLY B  46
SER B 494
LEU B 485
 None
 0.67A 5o96C-1cp9B:
undetectable		 5o96C-1cp9B:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 1cp9 PENICILLIN G AMIDASE
(Providencia
rettgeri) 		5 / 12 LEU B 400
GLY B 360
PHE B 414
ILE B 423
THR B 430
 None
 0.96A 5veuH-1cp9B:
0.0		 5veuH-1cp9B:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1cp9 PENICILLIN G AMIDASE
PENICILLIN G AMIDASE
(Providencia
rettgeri;
Providencia
rettgeri) 		4 / 8 GLY B  39
PHE B  42
HIS B  38
GLY A  28
 None
 0.77A 6hu9H-1cp9B:
undetectable
6hu9e-1cp9B:
0.0		 6hu9H-1cp9B:
9.74
6hu9e-1cp9B:
13.58