SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
(Microchaete
diplosiphon) 		5 / 9 TYR A  91
LEU A 133
ILE A 115
ALA A 172
SER A 174
 None
 1.20A 1eqgA-1cpcA:
undetectable		 1eqgA-1cpcA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
(Microchaete
diplosiphon) 		3 / 3 LEU A  92
VAL A  95
LEU A  99
 None
 0.50A 1mz9B-1cpcA:
1.3		 1mz9B-1cpcA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon;
Microchaete
diplosiphon) 		3 / 3 ALA A  41
GLY B  21
SER B  28
 None
 0.59A 2ivuA-1cpcA:
undetectable		 2ivuA-1cpcA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
(Microchaete
diplosiphon) 		5 / 12 THR A  96
ALA A  52
ALA A  55
ILE A 166
LEU A 173
 None
 1.15A 2nyrA-1cpcA:
undetectable		 2nyrA-1cpcA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1cpc C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon) 		4 / 6 LEU B  92
ALA B 139
LEU B 141
ALA B 144
 None
 0.93A 2vcvK-1cpcB:
undetectable		 2vcvK-1cpcB:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon) 		5 / 12 ILE B  51
PHE B 166
ALA B 101
LEU A  19
ILE B  44
 None
 1.29A 2xkwB-1cpcB:
undetectable		 2xkwB-1cpcB:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
(Microchaete
diplosiphon) 		4 / 5 ILE A 115
ASN A 171
TYR A 168
ILE A 112
 None
 1.06A 4jtpA-1cpcA:
undetectable		 4jtpA-1cpcA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1cpc C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon) 		5 / 12 LEU B 107
ALA B 169
ILE B  99
ALA B  98
ILE B  44
 None
 0.97A 4o2bD-1cpcB:
undetectable		 4o2bD-1cpcB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1cpc C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon) 		5 / 12 LEU B 107
ALA B 169
ILE B  99
ALA B  98
ILE B  44
 None
 0.98A 5eypB-1cpcB:
undetectable		 5eypB-1cpcB:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 1cpc C-PHYCOCYANIN (ALPHA
SUBUNIT)
C-PHYCOCYANIN (BETA
SUBUNIT)
(Microchaete
diplosiphon;
Microchaete
diplosiphon) 		4 / 4 SER B  10
THR A   6
ASP A  13
ASP B 103
 None
 1.44A 5vimB-1cpcB:
undetectable		 5vimB-1cpcB:
20.60