SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 SER A  83
ALA A  24
THR A  57
ILE A  29
 None
 0.79A 1c9sI-1cpnA:
1.0
1c9sJ-1cpnA:
1.1		 1c9sI-1cpnA:
15.35
1c9sJ-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.76A 1c9sU-1cpnA:
2.0
1c9sV-1cpnA:
0.0		 1c9sU-1cpnA:
15.35
1c9sV-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 7 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.78A 1gtnA-1cpnA:
2.3
1gtnK-1cpnA:
1.0		 1gtnA-1cpnA:
15.35
1gtnK-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 SER A  83
ALA A  24
THR A  57
ILE A  29
 None
 0.76A 1gtnA-1cpnA:
2.1
1gtnB-1cpnA:
1.2		 1gtnA-1cpnA:
15.35
1gtnB-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 SER A  83
ALA A  24
THR A  57
ILE A  29
 None
 0.77A 1gtnE-1cpnA:
1.1
1gtnF-1cpnA:
1.1		 1gtnE-1cpnA:
15.35
1gtnF-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.77A 1gtnP-1cpnA:
0.0
1gtnQ-1cpnA:
0.0		 1gtnP-1cpnA:
15.35
1gtnQ-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TRP A 188
PHE A 184
TRP A 126
 None
 1.47A 1r15C-1cpnA:
0.0		 1r15C-1cpnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TRP A 188
PHE A 184
TRP A 126
 None
 1.48A 1r15F-1cpnA:
0.0		 1r15F-1cpnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TRP A 188
PHE A 184
TRP A 126
 None
 1.48A 1r15G-1cpnA:
0.0		 1r15G-1cpnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TRP A 188
PHE A 184
TRP A 126
 None
 1.48A 1r15H-1cpnA:
undetectable		 1r15H-1cpnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.78A 1utdB-1cpnA:
0.9
1utdC-1cpnA:
0.9		 1utdB-1cpnA:
15.35
1utdC-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.76A 1utdF-1cpnA:
0.9
1utdG-1cpnA:
1.0		 1utdF-1cpnA:
15.35
1utdG-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.77A 1utdI-1cpnA:
1.0
1utdJ-1cpnA:
1.0		 1utdI-1cpnA:
15.35
1utdJ-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 8 ALA A  24
THR A  57
ILE A  29
SER A  83
 None
 0.76A 1utdJ-1cpnA:
1.0
1utdK-1cpnA:
0.8		 1utdJ-1cpnA:
15.35
1utdK-1cpnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TYR A 166
GLU A 162
THR A   9
 None
 1.02A 2y7hB-1cpnA:
undetectable		 2y7hB-1cpnA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 TYR A 166
GLU A 162
ASN A  10
 None
 0.97A 2y7hC-1cpnA:
0.0		 2y7hC-1cpnA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		4 / 5 GLY A  85
SER A  83
ALA A  82
PHE A  86
 None
 1.01A 4m93B-1cpnA:
undetectable
4m93C-1cpnA:
undetectable		 4m93B-1cpnA:
23.14
4m93C-1cpnA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		5 / 12 LEU A  53
ASP A 133
ASP A 132
TYR A 138
GLY A 128
 None
 1.11A 4qb9E-1cpnA:
0.0		 4qb9E-1cpnA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 PHE A  91
ILE A  50
ASP A 103
 None
 0.72A 5cswA-1cpnA:
0.0		 5cswA-1cpnA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1cpn CIRCULARLY PERMUTED
(Paenibacillus
macerans) 		3 / 3 PHE A  91
ILE A  50
ASP A 103
 None
 0.69A 5cswB-1cpnA:
0.0		 5cswB-1cpnA:
19.86