SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.35A 1v54A-1cpyA:
0.1
1v54C-1cpyA:
undetectable		 1v54A-1cpyA:
20.45
1v54C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 1v54N-1cpyA:
0.0
1v54P-1cpyA:
0.0		 1v54N-1cpyA:
20.45
1v54P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 1v55A-1cpyA:
0.2
1v55C-1cpyA:
undetectable		 1v55A-1cpyA:
20.45
1v55C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		3 / 3 ASN A  51
TRP A  49
GLN A  95
 None
 1.09A 1xoqA-1cpyA:
undetectable		 1xoqA-1cpyA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 4 GLY A  52
SER A 146
ILE A 340
HIS A 397
 None
 1.33A 1yajJ-1cpyA:
8.9		 1yajJ-1cpyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 4 GLY A  53
SER A 146
ILE A 340
HIS A 397
 None
 1.02A 1yajJ-1cpyA:
8.9		 1yajJ-1cpyA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 11 ILE A 159
ARG A 165
PHE A 155
GLY A 116
LYS A 117
 None
 1.29A 2bxmA-1cpyA:
0.0		 2bxmA-1cpyA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2dyrA-1cpyA:
0.0
2dyrC-1cpyA:
undetectable		 2dyrA-1cpyA:
20.45
2dyrC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2dyrN-1cpyA:
0.0
2dyrP-1cpyA:
0.0		 2dyrN-1cpyA:
20.45
2dyrP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2dysA-1cpyA:
0.6
2dysC-1cpyA:
undetectable		 2dysA-1cpyA:
20.45
2dysC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2dysN-1cpyA:
0.4
2dysP-1cpyA:
undetectable		 2dysN-1cpyA:
20.45
2dysP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 2eijA-1cpyA:
0.2
2eijC-1cpyA:
undetectable		 2eijA-1cpyA:
20.45
2eijC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2eijN-1cpyA:
0.2
2eijP-1cpyA:
undetectable		 2eijN-1cpyA:
20.45
2eijP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 2eikA-1cpyA:
0.1
2eikC-1cpyA:
undetectable		 2eikA-1cpyA:
20.45
2eikC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 2eikN-1cpyA:
0.2
2eikP-1cpyA:
undetectable		 2eikN-1cpyA:
20.45
2eikP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 2eilA-1cpyA:
0.3
2eilC-1cpyA:
undetectable		 2eilA-1cpyA:
20.45
2eilC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 2eilN-1cpyA:
0.3
2eilP-1cpyA:
undetectable		 2eilN-1cpyA:
20.45
2eilP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 2eimA-1cpyA:
0.4
2eimC-1cpyA:
undetectable		 2eimA-1cpyA:
20.45
2eimC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.33A 2eimN-1cpyA:
0.6
2eimP-1cpyA:
0.0		 2eimN-1cpyA:
20.45
2eimP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.34A 2einA-1cpyA:
1.0
2einC-1cpyA:
undetectable		 2einA-1cpyA:
20.45
2einC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 2einN-1cpyA:
0.0
2einP-1cpyA:
0.0		 2einN-1cpyA:
20.45
2einP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 10 GLY A 219
LEU A 220
LEU A 218
ARG A 216
TYR A 239
 None
 1.07A 2f8dA-1cpyA:
undetectable		 2f8dA-1cpyA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 ALA A 145
TRP A  49
LEU A  48
ALA A 148
 None
 1.29A 2jstA-1cpyA:
undetectable
2jstB-1cpyA:
0.0		 2jstA-1cpyA:
9.50
2jstB-1cpyA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR A 151
VAL A 154
SER A  58
TYR A 316
 None
 1.30A 2y05A-1cpyA:
undetectable
2y05B-1cpyA:
undetectable		 2y05A-1cpyA:
22.05
2y05B-1cpyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 2y69A-1cpyA:
0.0
2y69C-1cpyA:
undetectable		 2y69A-1cpyA:
20.45
2y69C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.34A 2y69P-1cpyA:
1.0
2y69W-1cpyA:
0.0		 2y69P-1cpyA:
19.39
2y69W-1cpyA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 2zxwA-1cpyA:
0.6
2zxwC-1cpyA:
undetectable		 2zxwA-1cpyA:
20.45
2zxwC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.35A 2zxwN-1cpyA:
0.3
2zxwP-1cpyA:
undetectable		 2zxwN-1cpyA:
20.45
2zxwP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.35A 3abkA-1cpyA:
0.1
3abkC-1cpyA:
undetectable		 3abkA-1cpyA:
20.45
3abkC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.42A 3abkN-1cpyA:
0.0
3abkP-1cpyA:
undetectable		 3abkN-1cpyA:
20.45
3abkP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 3abmN-1cpyA:
0.1
3abmP-1cpyA:
undetectable		 3abmN-1cpyA:
20.45
3abmP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 3ag1A-1cpyA:
0.5
3ag1C-1cpyA:
0.0		 3ag1A-1cpyA:
20.45
3ag1C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.41A 3ag1N-1cpyA:
0.6
3ag1P-1cpyA:
0.0		 3ag1N-1cpyA:
20.45
3ag1P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 3ag2A-1cpyA:
0.3
3ag2C-1cpyA:
undetectable		 3ag2A-1cpyA:
20.45
3ag2C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 3ag2N-1cpyA:
0.1
3ag2P-1cpyA:
undetectable		 3ag2N-1cpyA:
20.45
3ag2P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.33A 3ag3C-1cpyA:
0.0
3ag3J-1cpyA:
0.0		 3ag3C-1cpyA:
19.39
3ag3J-1cpyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 3ag3A-1cpyA:
0.2
3ag3C-1cpyA:
undetectable		 3ag3A-1cpyA:
20.45
3ag3C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 3ag3N-1cpyA:
0.0
3ag3P-1cpyA:
undetectable		 3ag3N-1cpyA:
20.45
3ag3P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 3ag4A-1cpyA:
0.5
3ag4C-1cpyA:
undetectable		 3ag4A-1cpyA:
20.45
3ag4C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 3ag4N-1cpyA:
0.2
3ag4P-1cpyA:
undetectable		 3ag4N-1cpyA:
20.45
3ag4P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 3asnA-1cpyA:
0.5
3asnC-1cpyA:
0.0		 3asnA-1cpyA:
20.45
3asnC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 401
ASP A 257
TYR A 269
PRO A 404
 None
 0.97A 3jq7B-1cpyA:
4.3		 3jq7B-1cpyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 401
ASP A 257
TYR A 269
PRO A 404
 None
 1.02A 3jq7C-1cpyA:
4.3		 3jq7C-1cpyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 GLY A  52
GLY A  53
SER A 146
HIS A 397
 None
 0.82A 3o9mB-1cpyA:
12.1		 3o9mB-1cpyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 184
THR A 350
ASN A 346
 None
 0.87A 3v4tE-1cpyA:
0.0		 3v4tE-1cpyA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 197
GLY A 196
GLU A 198
ILE A 258
 None
 0.79A 4fglD-1cpyA:
2.4		 4fglD-1cpyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  66
ALA A 148
ASP A 338
CYH A 341
GLY A 396
 None
 1.16A 4hfpB-1cpyA:
0.0		 4hfpB-1cpyA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 333
TRP A  49
ALA A 148
GLN A 184
GLY A 335
 None
 1.37A 4iilA-1cpyA:
2.2		 4iilA-1cpyA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 119
ILE A 174
GLY A 144
ILE A  91
LEU A 123
 None
 1.02A 4iv0A-1cpyA:
undetectable		 4iv0A-1cpyA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 119
ILE A 174
GLY A 144
ILE A  91
LEU A 123
 None
 1.01A 4mwzB-1cpyA:
undetectable		 4mwzB-1cpyA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  67
ASN A  80
ASP A  11
SER A  58
ASN A  85
 None
 1.18A 4pooA-1cpyA:
0.0		 4pooA-1cpyA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 5b1aN-1cpyA:
0.0
5b1aP-1cpyA:
undetectable		 5b1aN-1cpyA:
20.45
5b1aP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.39A 5b1bN-1cpyA:
0.3
5b1bP-1cpyA:
undetectable		 5b1bN-1cpyA:
20.45
5b1bP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 5b3sN-1cpyA:
0.3
5b3sP-1cpyA:
0.0		 5b3sN-1cpyA:
20.45
5b3sP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 198
TRP A 343
ASN A 394
 None
 1.15A 5dv4A-1cpyA:
0.0		 5dv4A-1cpyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 5iy5A-1cpyA:
0.8
5iy5C-1cpyA:
undetectable		 5iy5A-1cpyA:
20.45
5iy5C-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.33A 5wauC-1cpyA:
0.0
5wauJ-1cpyA:
0.0		 5wauC-1cpyA:
19.39
5wauJ-1cpyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.32A 5wauc-1cpyA:
0.0
5wauj-1cpyA:
0.0		 5wauc-1cpyA:
19.39
5wauj-1cpyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 5x19N-1cpyA:
0.0
5x19P-1cpyA:
0.0		 5x19N-1cpyA:
20.45
5x19P-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.33A 5x1bN-1cpyA:
0.0
5x1bP-1cpyA:
0.3		 5x1bN-1cpyA:
20.45
5x1bP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 5x1fN-1cpyA:
0.1
5x1fP-1cpyA:
0.0		 5x1fN-1cpyA:
20.45
5x1fP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.29A 5xdqC-1cpyA:
0.0
5xdqJ-1cpyA:
0.0		 5xdqC-1cpyA:
19.39
5xdqJ-1cpyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  32
PHE A  31
LEU A  59
PHE A  63
 None
 1.32A 5xdqP-1cpyA:
1.0
5xdqW-1cpyA:
0.0		 5xdqP-1cpyA:
19.39
5xdqW-1cpyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.37A 5zcqN-1cpyA:
0.3
5zcqP-1cpyA:
undetectable		 5zcqN-1cpyA:
20.45
5zcqP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  91
GLN A  95
THR A  18
LEU A  62
 None
 1.13A 6f3mD-1cpyA:
undetectable		 6f3mD-1cpyA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 277
ILE A  71
PRO A  77
LEU A  75
 None
 1.41A 6mkeB-1cpyA:
0.0		 6mkeB-1cpyA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 277
ILE A  71
PRO A  77
LEU A  75
 None
 1.43A 6mkeA-1cpyA:
0.0		 6mkeA-1cpyA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.38A 6nknA-1cpyA:
0.1
6nknC-1cpyA:
undetectable		 6nknA-1cpyA:
20.45
6nknC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.42A 6nmfN-1cpyA:
0.4
6nmfP-1cpyA:
0.0		 6nmfN-1cpyA:
20.45
6nmfP-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.36A 6nmpA-1cpyA:
0.0
6nmpC-1cpyA:
0.0		 6nmpA-1cpyA:
20.45
6nmpC-1cpyA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1cpy SERINE
CARBOXYPEPTIDASE
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 180
THR A 179
TYR A 316
HIS A 397
 None
 1.42A 6nmpN-1cpyA:
0.6
6nmpP-1cpyA:
undetectable		 6nmpN-1cpyA:
20.45
6nmpP-1cpyA:
19.39