SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		4 / 5 ASP A  20
SER A  99
ASN A 150
SER A 217
 None
 1.48A 1kiaB-1cq3A:
undetectable		 1kiaB-1cq3A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		4 / 6 ASP A  20
SER A  99
ASN A 150
SER A 217
 None
 1.48A 1kiaC-1cq3A:
undetectable		 1kiaC-1cq3A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		3 / 3 SER A 119
HIS A  16
ASP A 108
 None
 0.62A 2wa2B-1cq3A:
undetectable		 2wa2B-1cq3A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 12 SER A 133
ASN A  34
THR A  71
ILE A  37
SER A 139
 None
 1.33A 2xrlA-1cq3A:
undetectable		 2xrlA-1cq3A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 12 VAL A  66
LEU A  70
THR A  71
ASP A 168
THR A  31
 None
 1.15A 3a35B-1cq3A:
0.2		 3a35B-1cq3A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_2
(VITAMIN D3 RECEPTOR)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 9 PHE A  76
ILE A  23
LEU A 214
TYR A 199
VAL A 167
 None
 1.37A 3m7rA-1cq3A:
undetectable		 3m7rA-1cq3A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 12 GLY A 163
GLY A 196
VAL A  21
ALA A 204
ASP A 207
 None
 1.16A 3qowA-1cq3A:
undetectable		 3qowA-1cq3A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 12 GLY A  91
ARG A  97
GLY A  68
SER A  89
ALA A  96
 None
 1.21A 3sueB-1cq3A:
undetectable		 3sueB-1cq3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		4 / 4 VAL A  94
GLU A  87
GLY A  68
LEU A  70
 None
 1.02A 5g5gC-1cq3A:
0.0		 5g5gC-1cq3A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1cq3 VIRAL CHEMOKINE
INHIBITOR
(Cowpox
virus) 		5 / 12 GLY A 163
GLY A 196
VAL A  21
ALA A 204
ASP A 207
 None
 1.03A 6nj9K-1cq3A:
undetectable		 6nj9K-1cq3A:
22.38