SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 12 ILE B 368
GLY B 331
GLY B 334
LEU B 327
VAL B 323
 None
 1.14A 1i9gA-1cqiB:
2.1		 1i9gA-1cqiB:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 5 LEU B 287
ILE B 305
LEU B 306
SER B 307
 None
 0.96A 2byoA-1cqiB:
0.0		 2byoA-1cqiB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		3 / 3 LEU B 110
LEU B 149
PHE B 177
 None
 0.72A 2pgrA-1cqiB:
2.1		 2pgrA-1cqiB:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 5 VAL B 316
VAL B 347
GLN B 380
PHE B 319
 None
 1.39A 3bjwB-1cqiB:
0.0		 3bjwB-1cqiB:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 12 ILE B 332
VAL B 347
ILE B 318
LEU B 327
VAL B 298
 None
 1.14A 3fpjB-1cqiB:
4.1		 3fpjB-1cqiB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 8 ILE B 180
LEU B 184
PHE B  12
GLY B 214
 None
 0.82A 3selX-1cqiB:
undetectable		 3selX-1cqiB:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 7 ILE B 180
LEU B 184
PHE B  12
GLY B 214
 None
 0.94A 4hajA-1cqiB:
undetectable		 4hajA-1cqiB:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 8 ILE B 180
LEU B 184
PHE B  12
GLY B 214
 None
 0.85A 4hb6A-1cqiB:
undetectable		 4hb6A-1cqiB:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 9 VAL B 263
ILE B 318
ARG B 348
LEU B 349
GLY B 331
 None
 1.12A 4kukA-1cqiB:
undetectable		 4kukA-1cqiB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 6 ILE B 180
PHE B 181
GLY B 183
LEU B 201
 None
 0.72A 4o8fB-1cqiB:
0.0		 4o8fB-1cqiB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 8 ALA B 254
GLU B 242
ALA B 246
TYR B 252
LEU B 287
 None
 1.46A 4v1fA-1cqiB:
0.0
4v1fB-1cqiB:
undetectable		 4v1fA-1cqiB:
14.36
4v1fB-1cqiB:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 11 LEU B 173
VAL B 174
LEU B 110
GLY B 160
LEU B 167
 None
 1.06A 4zbqA-1cqiB:
2.1		 4zbqA-1cqiB:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		4 / 5 LEU B 201
ALA B 125
LEU B 108
VAL B 147
 None
 1.17A 5cr1A-1cqiB:
0.0		 5cr1A-1cqiB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1cqi PROTEIN
(SUCCINYL-COA
SYNTHETASE BETA
CHAIN)
(Escherichia
coli) 		5 / 12 ASN B 285
PRO B 283
ILE B 259
ILE B 305
VAL B 381
 None
 1.17A 6j21A-1cqiB:
0.0		 6j21A-1cqiB:
21.24