SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4003_1 (SERUM ALBUMIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 9	ILE A 93 VAL A 175 GLY A 176 CYH A 123 LEU A 3	None	1.18A	1e7bA-1cqjA: undetectable	1e7bA-1cqjA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_D_TRPD81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 7	VAL A 150 GLY A 148 THR A 200 ILE A 203	None	0.46A	1gtnC-1cqjA: undetectable 1gtnD-1cqjA: undetectable	1gtnC-1cqjA: 13.79 1gtnD-1cqjA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_A_NIOA604_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 5	SER A 1 THR A 173 GLU A 131 GLY A 130	None	1.27A	1icrA-1cqjA: 0.1 1icrB-1cqjA: 0.0	1icrA-1cqjA: 21.45 1icrB-1cqjA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICR_B_NIOB602_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 5	GLU A 131 GLY A 130 SER A 1 THR A 173	None	1.28A	1icrA-1cqjA: 0.1 1icrB-1cqjA: 0.0	1icrA-1cqjA: 21.45 1icrB-1cqjA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_C_NIOC708_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 5	SER A 1 THR A 173 GLU A 131 GLY A 130	None	1.28A	1icvC-1cqjA: 0.1 1icvD-1cqjA: 0.0	1icvC-1cqjA: 21.45 1icvD-1cqjA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICV_D_NIOD706_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 5	GLU A 131 GLY A 130 SER A 1 THR A 173	None	1.28A	1icvC-1cqjA: 0.1 1icvD-1cqjA: 0.0	1icvC-1cqjA: 21.45 1icvD-1cqjA: 21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQB_B_BEZB525_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 5	GLU A 131 GLY A 130 SER A 1 THR A 173	None	1.31A	1kqbA-1cqjA: 0.0 1kqbB-1cqjA: 0.0	1kqbA-1cqjA: 20.83 1kqbB-1cqjA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PKV_A_RBFA100_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	THR A 128 ILE A 127 THR A 173 ILE A 134 VAL A 126	None	1.22A	1pkvA-1cqjA: undetectable 1pkvB-1cqjA: undetectable	1pkvA-1cqjA: 19.11 1pkvB-1cqjA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PKV_B_RBFB101_1 (RIBOFLAVIN SYNTHASE ALPHA CHAIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	ILE A 134 VAL A 126 THR A 128 ILE A 127 THR A 173	None	1.19A	1pkvA-1cqjA: undetectable 1pkvB-1cqjA: undetectable	1pkvA-1cqjA: 19.11 1pkvB-1cqjA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2001_1 (SERUM ALBUMIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	ILE A 93 VAL A 175 GLY A 176 CYH A 123 LEU A 3	None	1.09A	2bxeA-1cqjA: undetectable	2bxeA-1cqjA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2001_1 (SERUM ALBUMIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 93 CYH A 123 VAL A 175 GLY A 176 LEU A 3	None	1.07A	2bxeB-1cqjA: undetectable	2bxeB-1cqjA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2001_1 (SERUM ALBUMIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 93 VAL A 175 GLY A 176 CYH A 123 LEU A 3	None	1.16A	2bxeB-1cqjA: undetectable	2bxeB-1cqjA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	GLY A 176 GLY A 184 GLY A 120 ILE A 182 ASP A 180	None	1.06A	2nxeB-1cqjA: 6.9	2nxeB-1cqjA: 23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q83_A_ADNA1_1 (YTAA PROTEIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 7	ILE A 177 ILE A 92 LEU A 91 ILE A 93	None	0.83A	2q83A-1cqjA: 0.0	2q83A-1cqjA: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	GLY A 176 GLY A 184 GLY A 120 ILE A 182 ASP A 180	None	1.11A	2zbpA-1cqjA: 6.7	2zbpA-1cqjA: 23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_A_VD3A701_1 (CYTOCHROME P450 2R1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ALA A 84 ALA A 114 THR A 8 VAL A 10 ILE A 93	None	1.08A	3c6gA-1cqjA: 0.0	3c6gA-1cqjA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_1 (CYTOCHROME P450 2R1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ALA A 84 ALA A 114 THR A 8 VAL A 10 ILE A 93	None	1.05A	3czhA-1cqjA: 0.0	3czhA-1cqjA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_B_D2VB602_1 (CYTOCHROME P450 2R1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ALA A 84 ALA A 114 THR A 8 VAL A 10 ILE A 93	None	1.03A	3czhB-1cqjA: 0.0	3czhB-1cqjA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_A_NCAA302_0 (ADP-RIBOSYL CYCLASE 1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 7	LYS A 162 LEU A 276 GLU A 159 SER A 275	None	1.47A	3dzgA-1cqjA: 2.7	3dzgA-1cqjA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E4E_A_4PZA501_1 (CYTOCHROME P450 2E1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	3 / 3	ALA A 160 THR A 164 CYH A 174	None	0.68A	3e4eA-1cqjA: undetectable	3e4eA-1cqjA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E4E_B_4PZB501_1 (CYTOCHROME P450 2E1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	3 / 3	ALA A 160 THR A 164 CYH A 174	None	0.57A	3e4eB-1cqjA: undetectable	3e4eB-1cqjA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_C_ROFC903_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	3 / 3	SER A 18 GLN A 19 PHE A 22	COA A 901 (-3.1A) COA A 901 (-4.9A) None	0.54A	3g4lC-1cqjA: 0.2	3g4lC-1cqjA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 177 GLY A 178 GLY A 179 ALA A 247 PRO A 124	None None None None COA A 901 (-4.1A)	1.05A	3jayA-1cqjA: 0.0	3jayA-1cqjA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 177 GLY A 178 GLY A 179 ALA A 247 PRO A 124	None None None None COA A 901 (-4.1A)	1.00A	3jb2A-1cqjA: 0.0	3jb2A-1cqjA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_B_CL6B506_1 (CHOLESTEROL 24-HYDROXYLASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	6 / 12	LEU A 48 THR A 32 ILE A 28 ALA A 27 GLU A 25 THR A 21	None	1.41A	3mdvB-1cqjA: 0.0	3mdvB-1cqjA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RF4_A_FUNA201_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	SER A 185 ILE A 119 VAL A 175 VAL A 126 ILE A 2	None	1.26A	3rf4A-1cqjA: 0.0 3rf4C-1cqjA: 0.0	3rf4A-1cqjA: 14.54 3rf4C-1cqjA: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RF4_B_FUNB202_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	ILE A 2 SER A 185 ILE A 119 VAL A 175 VAL A 126	None	1.20A	3rf4A-1cqjA: 0.0 3rf4B-1cqjA: 0.0	3rf4A-1cqjA: 14.54 3rf4B-1cqjA: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RF4_C_FUNC203_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 11	ILE A 2 SER A 185 ILE A 119 VAL A 175 VAL A 126	None	1.26A	3rf4B-1cqjA: undetectable 3rf4C-1cqjA: 0.0	3rf4B-1cqjA: 14.54 3rf4C-1cqjA: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TAJ_A_NBOA700_1 (LACTOTRANSFERRIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 7	GLY A 41 PRO A 40 ASN A 54 GLY A 14	None COA A 901 (-4.4A) None COA A 901 (-3.6A)	0.84A	3tajA-1cqjA: undetectable	3tajA-1cqjA: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_D_CVID301_0 (PUTATIVE REGULATORY PROTEIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 206 SER A 153 ILE A 119 VAL A 229 PHE A 187	None PO4 A 906 (-3.0A) None None None	1.04A	3vw1D-1cqjA: 0.0	3vw1D-1cqjA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FJP_A_NPSA711_1 (LACTOTRANSFERRIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 6	GLY A 41 PRO A 40 ASN A 54 GLY A 14	None COA A 901 (-4.4A) None COA A 901 (-3.6A)	0.86A	4fjpA-1cqjA: undetectable	4fjpA-1cqjA: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_C_OBNC2004_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	GLU A 192 GLY A 148 THR A 128 ILE A 127 ARG A 117	None	1.20A	4hytC-1cqjA: 0.0	4hytC-1cqjA: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_A_SAMA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	GLY A 125 GLY A 176 ILE A 127 CYH A 174 ILE A 134	None	0.96A	4iv0A-1cqjA: 4.1	4iv0A-1cqjA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_A_SAMA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	TYR A 158 GLY A 125 GLY A 176 ILE A 127 ILE A 134	None	0.91A	4iv0A-1cqjA: 4.1	4iv0A-1cqjA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_B_SAMB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	TYR A 158 GLY A 125 GLY A 176 ILE A 127 ILE A 134	None	0.92A	4iv0B-1cqjA: 4.3	4iv0B-1cqjA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_A_SAMA301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	TYR A 158 GLY A 125 GLY A 176 ILE A 127 ILE A 134	None	0.89A	4mwzA-1cqjA: 4.3	4mwzA-1cqjA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWZ_B_SAMB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	TYR A 158 GLY A 125 GLY A 176 ILE A 127 ILE A 134	None	0.94A	4mwzB-1cqjA: 4.1	4mwzB-1cqjA: 22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 6	ILE A 279 ILE A 221 ILE A 149 LEU A 283	None	0.75A	4o8fB-1cqjA: undetectable	4o8fB-1cqjA: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_A_GCSA303_1 (CHITOSANASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 6	GLU A 195 ILE A 203 THR A 200 TYR A 220	None	1.50A	4qwpA-1cqjA: 0.0	4qwpA-1cqjA: 24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RVG_A_SAMA503_0 (D-MYCAROSE 3-C-METHYLTRANSFERAS E)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	ILE A 119 GLY A 120 ASN A 122 PRO A 183 ILE A 190	None None COA A 901 (-4.7A) None None	1.12A	4rvgA-1cqjA: 4.6	4rvgA-1cqjA: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE2_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	LEU A 191 ILE A 149 PHE A 187 GLY A 207 LEU A 265	None	1.14A	4ze2A-1cqjA: 0.0	4ze2A-1cqjA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVM_A_DM2A303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	5 / 12	GLY A 154 THR A 157 GLU A 208 ILE A 206 ILE A 177	PO4 A 906 (-3.8A) None None None None	1.25A	4zvmA-1cqjA: 4.7 4zvmB-1cqjA: 5.0	4zvmA-1cqjA: 21.81 4zvmB-1cqjA: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DQY_A_BEZA401_0 (THIOREDOXIN)	1cqj	SUCCINYL-COA SYNTHETASE ALPHA CHAIN (Escherichia coli)	4 / 8	ILE A 95 GLN A 13 SER A 80 CYH A 77	COA A 901 (-4.8A) None COA A 901 (-4.2A) None	1.16A	5dqyA-1cqjA: 0.0	5dqyA-1cqjA: 19.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4003_1","SERUM ALBUMIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A  93;VAL A 175;GLY A 176;CYH A 123;LEU A   3","None","1.18A","1e7bA-1cqjA:undetectable","1e7bA-1cqjA:18.57"],["1GTN_D_TRPD81_0","TRP RNA-BINDING ATTENUATION PROTEIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"VAL A 150;GLY A 148;THR A 200;ILE A 203","None","0.46A","1gtnC-1cqjA:undetectable;1gtnD-1cqjA:undetectable","1gtnC-1cqjA:13.79;1gtnD-1cqjA:13.79"],["1ICR_A_NIOA604_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"SER A   1;THR A 173;GLU A 131;GLY A 130","None","1.27A","1icrA-1cqjA:0.1;1icrB-1cqjA:0.0","1icrA-1cqjA:21.45;1icrB-1cqjA:21.45"],["1ICR_B_NIOB602_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLU A 131;GLY A 130;SER A   1;THR A 173","None","1.28A","1icrA-1cqjA:0.1;1icrB-1cqjA:0.0","1icrA-1cqjA:21.45;1icrB-1cqjA:21.45"],["1ICV_C_NIOC708_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"SER A   1;THR A 173;GLU A 131;GLY A 130","None","1.28A","1icvC-1cqjA:0.1;1icvD-1cqjA:0.0","1icvC-1cqjA:21.45;1icvD-1cqjA:21.45"],["1ICV_D_NIOD706_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLU A 131;GLY A 130;SER A   1;THR A 173","None","1.28A","1icvC-1cqjA:0.1;1icvD-1cqjA:0.0","1icvC-1cqjA:21.45;1icvD-1cqjA:21.45"],["1KQB_B_BEZB525_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLU A 131;GLY A 130;SER A   1;THR A 173","None","1.31A","1kqbA-1cqjA:0.0;1kqbB-1cqjA:0.0","1kqbA-1cqjA:20.83;1kqbB-1cqjA:20.83"],["1PKV_A_RBFA100_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"THR A 128;ILE A 127;THR A 173;ILE A 134;VAL A 126","None","1.22A","1pkvA-1cqjA:undetectable;1pkvB-1cqjA:undetectable","1pkvA-1cqjA:19.11;1pkvB-1cqjA:19.11"],["1PKV_B_RBFB101_1","RIBOFLAVIN SYNTHASE ALPHA CHAIN;RIBOFLAVIN SYNTHASE ALPHA CHAIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A 134;VAL A 126;THR A 128;ILE A 127;THR A 173","None","1.19A","1pkvA-1cqjA:undetectable;1pkvB-1cqjA:undetectable","1pkvA-1cqjA:19.11;1pkvB-1cqjA:19.11"],["2BXE_A_1FLA2001_1","SERUM ALBUMIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A  93;VAL A 175;GLY A 176;CYH A 123;LEU A   3","None","1.09A","2bxeA-1cqjA:undetectable","2bxeA-1cqjA:18.57"],["2BXE_B_1FLB2001_1","SERUM ALBUMIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A  93;CYH A 123;VAL A 175;GLY A 176;LEU A   3","None","1.07A","2bxeB-1cqjA:undetectable","2bxeB-1cqjA:18.57"],["2BXE_B_1FLB2001_1","SERUM ALBUMIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A  93;VAL A 175;GLY A 176;CYH A 123;LEU A   3","None","1.16A","2bxeB-1cqjA:undetectable","2bxeB-1cqjA:18.57"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"GLY A 176;GLY A 184;GLY A 120;ILE A 182;ASP A 180","None","1.06A","2nxeB-1cqjA:6.9","2nxeB-1cqjA:23.79"],["2Q83_A_ADNA1_1","YTAA PROTEIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"ILE A 177;ILE A  92;LEU A  91;ILE A  93","None","0.83A","2q83A-1cqjA:0.0","2q83A-1cqjA:21.68"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"GLY A 176;GLY A 184;GLY A 120;ILE A 182;ASP A 180","None","1.11A","2zbpA-1cqjA:6.7","2zbpA-1cqjA:23.79"],["3C6G_A_VD3A701_1","CYTOCHROME P450 2R1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ALA A  84;ALA A 114;THR A   8;VAL A  10;ILE A  93","None","1.08A","3c6gA-1cqjA:0.0","3c6gA-1cqjA:19.26"],["3CZH_A_D2VA602_1","CYTOCHROME P450 2R1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ALA A  84;ALA A 114;THR A   8;VAL A  10;ILE A  93","None","1.05A","3czhA-1cqjA:0.0","3czhA-1cqjA:19.39"],["3CZH_B_D2VB602_1","CYTOCHROME P450 2R1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ALA A  84;ALA A 114;THR A   8;VAL A  10;ILE A  93","None","1.03A","3czhB-1cqjA:0.0","3czhB-1cqjA:19.39"],["3DZG_A_NCAA302_0","ADP-RIBOSYL CYCLASE 1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"LYS A 162;LEU A 276;GLU A 159;SER A 275","None","1.47A","3dzgA-1cqjA:2.7","3dzgA-1cqjA:20.39"],["3E4E_A_4PZA501_1","CYTOCHROME P450 2E1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",3,"ALA A 160;THR A 164;CYH A 174","None","0.68A","3e4eA-1cqjA:undetectable","3e4eA-1cqjA:21.26"],["3E4E_B_4PZB501_1","CYTOCHROME P450 2E1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",3,"ALA A 160;THR A 164;CYH A 174","None","0.57A","3e4eB-1cqjA:undetectable","3e4eB-1cqjA:21.26"],["3G4L_C_ROFC903_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",3,"SER A  18;GLN A  19;PHE A  22","COA A 901 (-3.1A);COA A 901 (-4.9A);None","0.54A","3g4lC-1cqjA:0.2","3g4lC-1cqjA:20.51"],["3JAY_A_SAMA1102_0","STRUCTURAL PROTEIN VP3","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A 177;GLY A 178;GLY A 179;ALA A 247;PRO A 124","None;None;None;None;COA A 901 (-4.1A)","1.05A","3jayA-1cqjA:0.0","3jayA-1cqjA:14.94"],["3JB2_A_SAMA1102_0","STRUCTURAL PROTEIN VP3","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A 177;GLY A 178;GLY A 179;ALA A 247;PRO A 124","None;None;None;None;COA A 901 (-4.1A)","1.00A","3jb2A-1cqjA:0.0","3jb2A-1cqjA:14.94"],["3MDV_B_CL6B506_1","CHOLESTEROL 24-HYDROXYLASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",6,"LEU A  48;THR A  32;ILE A  28;ALA A  27;GLU A  25;THR A  21","None","1.41A","3mdvB-1cqjA:0.0","3mdvB-1cqjA:19.13"],["3RF4_A_FUNA201_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"SER A 185;ILE A 119;VAL A 175;VAL A 126;ILE A   2","None","1.26A","3rf4A-1cqjA:0.0;3rf4C-1cqjA:0.0","3rf4A-1cqjA:14.54;3rf4C-1cqjA:14.54"],["3RF4_B_FUNB202_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A   2;SER A 185;ILE A 119;VAL A 175;VAL A 126","None","1.20A","3rf4A-1cqjA:0.0;3rf4B-1cqjA:0.0","3rf4A-1cqjA:14.54;3rf4B-1cqjA:14.54"],["3RF4_C_FUNC203_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A   2;SER A 185;ILE A 119;VAL A 175;VAL A 126","None","1.26A","3rf4B-1cqjA:undetectable;3rf4C-1cqjA:0.0","3rf4B-1cqjA:14.54;3rf4C-1cqjA:14.54"],["3TAJ_A_NBOA700_1","LACTOTRANSFERRIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLY A  41;PRO A  40;ASN A  54;GLY A  14","None;COA A 901 (-4.4A);None;COA A 901 (-3.6A)","0.84A","3tajA-1cqjA:undetectable","3tajA-1cqjA:21.31"],["3VW1_D_CVID301_0","PUTATIVE REGULATORY PROTEIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A 206;SER A 153;ILE A 119;VAL A 229;PHE A 187","None;PO4 A 906 (-3.0A);None;None;None","1.04A","3vw1D-1cqjA:0.0","3vw1D-1cqjA:21.84"],["4FJP_A_NPSA711_1","LACTOTRANSFERRIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLY A  41;PRO A  40;ASN A  54;GLY A  14","None;COA A 901 (-4.4A);None;COA A 901 (-3.6A)","0.86A","4fjpA-1cqjA:undetectable","4fjpA-1cqjA:21.93"],["4HYT_C_OBNC2004_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"GLU A 192;GLY A 148;THR A 128;ILE A 127;ARG A 117","None","1.20A","4hytC-1cqjA:0.0","4hytC-1cqjA:15.26"],["4IV0_A_SAMA302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"GLY A 125;GLY A 176;ILE A 127;CYH A 174;ILE A 134","None","0.96A","4iv0A-1cqjA:4.1","4iv0A-1cqjA:23.42"],["4IV0_A_SAMA302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"TYR A 158;GLY A 125;GLY A 176;ILE A 127;ILE A 134","None","0.91A","4iv0A-1cqjA:4.1","4iv0A-1cqjA:23.42"],["4IV0_B_SAMB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"TYR A 158;GLY A 125;GLY A 176;ILE A 127;ILE A 134","None","0.92A","4iv0B-1cqjA:4.3","4iv0B-1cqjA:23.42"],["4MWZ_A_SAMA301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"TYR A 158;GLY A 125;GLY A 176;ILE A 127;ILE A 134","None","0.89A","4mwzA-1cqjA:4.3","4mwzA-1cqjA:22.70"],["4MWZ_B_SAMB301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"TYR A 158;GLY A 125;GLY A 176;ILE A 127;ILE A 134","None","0.94A","4mwzB-1cqjA:4.1","4mwzB-1cqjA:22.70"],["4O8F_B_BRLB501_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"ILE A 279;ILE A 221;ILE A 149;LEU A 283","None","0.75A","4o8fB-1cqjA:undetectable","4o8fB-1cqjA:18.93"],["4QWP_A_GCSA303_1","CHITOSANASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"GLU A 195;ILE A 203;THR A 200;TYR A 220","None","1.50A","4qwpA-1cqjA:0.0","4qwpA-1cqjA:24.92"],["4RVG_A_SAMA503_0","D-MYCAROSE 3-C-METHYLTRANSFERASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"ILE A 119;GLY A 120;ASN A 122;PRO A 183;ILE A 190","None;None;COA A 901 (-4.7A);None;None","1.12A","4rvgA-1cqjA:4.6","4rvgA-1cqjA:20.97"],["4ZE2_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"LEU A 191;ILE A 149;PHE A 187;GLY A 207;LEU A 265","None","1.14A","4ze2A-1cqjA:0.0","4ze2A-1cqjA:21.13"],["4ZVM_A_DM2A303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",5,"GLY A 154;THR A 157;GLU A 208;ILE A 206;ILE A 177","PO4 A 906 (-3.8A);None;None;None;None","1.25A","4zvmA-1cqjA:4.7;4zvmB-1cqjA:5.0","4zvmA-1cqjA:21.81;4zvmB-1cqjA:21.81"],["5DQY_A_BEZA401_0","THIOREDOXIN","1cqj","SUCCINYL-COA SYNTHETASE ALPHA CHAIN","Escherichia coli",4,"ILE A  95;GLN A  13;SER A  80;CYH A  77","COA A 901 (-4.8A);None;COA A 901 (-4.2A);None","1.16A","5dqyA-1cqjA:0.0","5dqyA-1cqjA:19.23"]]