SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	5 / 12	ILE A 11 GLY A 148 ALA A 172 SER A 171 GLY A 29	None	1.15A	1nbiA-1cqqA: undetectable	1nbiA-1cqqA: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_F_URFF2001_1 (URIDINE PHOSPHORYLASE)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	4 / 7	GLY A 27 ILE A 160 VAL A 37 PRO A 38	None	1.07A	1rxcF-1cqqA: undetectable	1rxcF-1cqqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_L_URFL2071_1 (URIDINE PHOSPHORYLASE)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	4 / 7	GLY A 27 ILE A 160 VAL A 37 PRO A 38	None	1.07A	1rxcL-1cqqA: undetectable	1rxcL-1cqqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q0I_A_BEZA990_0 (QUINOLONE SIGNAL RESPONSE PROTEIN)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	4 / 8	GLU A 94 LEU A 175 SER A 121 LEU A 136	None	1.12A	2q0iA-1cqqA: undetectable	2q0iA-1cqqA: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_B_VD3B2001_1 (VITAMIN D HYDROXYLASE)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	5 / 11	ILE A 160 LEU A 70 ASN A 124 LEU A 174 PRO A 38	None	1.36A	3a50B-1cqqA: undetectable	3a50B-1cqqA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_C_CGEC501_1 (CYTOCHROME P450 2B4)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	5 / 9	VAL A 30 ILE A 90 ALA A 172 VAL A 150 VAL A 157	None	1.25A	3me6C-1cqqA: undetectable	3me6C-1cqqA: 17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HXY_B_ACAB502_1 (PLM1)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	4 / 7	VAL A 116 SER A 171 TYR A 138 LEU A 104	None	1.20A	4hxyB-1cqqA: undetectable	4hxyB-1cqqA: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM2_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	5 / 9	VAL A 150 LEU A 174 PHE A 179 VAL A 36 ILE A 160	None	1.19A	5om2A-1cqqA: 0.0 5om2B-1cqqA: undetectable	5om2A-1cqqA: 17.84 5om2B-1cqqA: 12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRZ_A_H8JA1206_0 (5HT2B RECEPTOR, BRIL CHIMERA)	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	5 / 12	VAL A 150 LEU A 174 GLY A 7 VAL A 119 TYR A 138	None	1.16A	6drzA-1cqqA: undetectable	6drzA-1cqqA: 19.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NBI_A_SAMA293_0","GLYCINE N-METHYLTRANSFERASE","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",5,"ILE A  11;GLY A 148;ALA A 172;SER A 171;GLY A  29","None","1.15A","1nbiA-1cqqA:undetectable","1nbiA-1cqqA:24.21"],["1RXC_F_URFF2001_1","URIDINE PHOSPHORYLASE","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",4,"GLY A  27;ILE A 160;VAL A  37;PRO A  38","None","1.07A","1rxcF-1cqqA:undetectable","1rxcF-1cqqA:20.00"],["1RXC_L_URFL2071_1","URIDINE PHOSPHORYLASE","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",4,"GLY A  27;ILE A 160;VAL A  37;PRO A  38","None","1.07A","1rxcL-1cqqA:undetectable","1rxcL-1cqqA:20.00"],["2Q0I_A_BEZA990_0","QUINOLONE SIGNAL RESPONSE PROTEIN","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",4,"GLU A  94;LEU A 175;SER A 121;LEU A 136","None","1.12A","2q0iA-1cqqA:undetectable","2q0iA-1cqqA:18.86"],["3A50_B_VD3B2001_1","VITAMIN D HYDROXYLASE","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",5,"ILE A 160;LEU A  70;ASN A 124;LEU A 174;PRO A  38","None","1.36A","3a50B-1cqqA:undetectable","3a50B-1cqqA:14.81"],["3ME6_C_CGEC501_1","CYTOCHROME P450 2B4","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",5,"VAL A  30;ILE A  90;ALA A 172;VAL A 150;VAL A 157","None","1.25A","3me6C-1cqqA:undetectable","3me6C-1cqqA:17.02"],["4HXY_B_ACAB502_1","PLM1","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",4,"VAL A 116;SER A 171;TYR A 138;LEU A 104","None","1.20A","4hxyB-1cqqA:undetectable","4hxyB-1cqqA:16.31"],["5OM2_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",5,"VAL A 150;LEU A 174;PHE A 179;VAL A  36;ILE A 160","None","1.19A","5om2A-1cqqA:0.0;5om2B-1cqqA:undetectable","5om2A-1cqqA:17.84;5om2B-1cqqA:12.21"],["6DRZ_A_H8JA1206_0","5HT2B RECEPTOR, BRIL CHIMERA","1cqq","TYPE 2 RHINOVIRUS 3C PROTEASE","Rhinovirus A",5,"VAL A 150;LEU A 174;GLY A   7;VAL A 119;TYR A 138","None","1.16A","6drzA-1cqqA:undetectable","6drzA-1cqqA:19.46"]]