SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cs1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 11 ALA A  79
GLU A  65
ALA A  70
LEU A 222
VAL A  57
 None
 1.03A 1ictA-1cs1A:
undetectable
1ictC-1cs1A:
0.0		 1ictA-1cs1A:
15.24
1ictC-1cs1A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 8 GLU A  65
ALA A  70
LEU A 222
ALA A  79
 None
 0.88A 1ie4B-1cs1A:
undetectable
1ie4D-1cs1A:
undetectable		 1ie4B-1cs1A:
15.86
1ie4D-1cs1A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 1jffB-1cs1A:
2.5		 1jffB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 7 SER A 204
ASP A 205
GLU A 331
GLU A 367
 None
 1.20A 1knyA-1cs1A:
0.0
1knyB-1cs1A:
0.0		 1knyA-1cs1A:
20.16
1knyB-1cs1A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 ASP A 173
LEU A 193
VAL A 192
ILE A 212
 LLP  A 198 ( 3.0A)
None
None
None
 1.03A 1s9qA-1cs1A:
undetectable		 1s9qA-1cs1A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 GLY A 234
GLY A 233
SER A 195
LEU A 240
LEU A  61
 None
None
LLP  A 198 ( 2.8A)
None
None
 0.97A 1ya4C-1cs1A:
undetectable		 1ya4C-1cs1A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 LEU A 162
LEU A 130
PRO A 138
VAL A  95
 None
 1.19A 2dqyC-1cs1A:
undetectable		 2dqyC-1cs1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 11 LEU A 275
LEU A 280
ILE A 262
THR A 364
LEU A 359
 None
 1.19A 2ft9A-1cs1A:
undetectable		 2ft9A-1cs1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 11 LEU A 275
LEU A 280
THR A 364
ASN A 258
LEU A 359
 None
 1.34A 2ft9A-1cs1A:
undetectable		 2ft9A-1cs1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 2hxfB-1cs1A:
2.6		 2hxfB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 2hxhB-1cs1A:
2.6		 2hxhB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 5 LEU A 150
VAL A  95
LEU A 120
ARG A 131
 None
 0.92A 2oiqA-1cs1A:
undetectable		 2oiqA-1cs1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 2p4nB-1cs1A:
2.6		 2p4nB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 ILE A  27
LEU A  29
LEU A 240
ASP A 237
 None
 1.08A 2rlfA-1cs1A:
0.0
2rlfD-1cs1A:
0.0		 2rlfA-1cs1A:
7.47
2rlfD-1cs1A:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 2wbeB-1cs1A:
2.9		 2wbeB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 TRP A 224
VAL A 219
TRP A 225
 None
 1.34A 2xdcE-1cs1A:
undetectable
2xdcF-1cs1A:
undetectable		 2xdcE-1cs1A:
13.92
2xdcF-1cs1A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 3dcoB-1cs1A:
2.8		 3dcoB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 3edlB-1cs1A:
2.8		 3edlB-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 VAL A 192
LEU A 241
LEU A 245
ARG A  54
GLY A  69
 None
 1.01A 3iz0B-1cs1A:
2.7		 3iz0B-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 ASP A  55
ARG A  59
ARG A  49
 None
 0.99A 3k37A-1cs1A:
undetectable		 3k37A-1cs1A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 PHE A 176
PHE A 314
PHE A 302
GLY A 379
ILE A 262
 None
 1.03A 3ld6B-1cs1A:
undetectable		 3ld6B-1cs1A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 LEU A  72
GLY A  76
ALA A  79
SER A  78
LEU A  82
 None
LLP  A 198 ( 3.2A)
None
None
None
 1.22A 3n8xA-1cs1A:
0.0		 3n8xA-1cs1A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 THR A  75
ASN A  74
GLY A 234
ASP A 237
 LLP  A 198 ( 4.0A)
None
None
None
 1.24A 3w9tE-1cs1A:
0.0		 3w9tE-1cs1A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 LEU A  72
GLY A  76
ALA A  79
SER A  78
LEU A  82
 None
LLP  A 198 ( 3.2A)
None
None
None
 1.16A 4coxC-1cs1A:
0.0		 4coxC-1cs1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 5 LEU A 140
ILE A  80
ALA A  96
PHE A 108
 None
 1.06A 4dc3B-1cs1A:
4.1		 4dc3B-1cs1A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 LEU A 372
LEU A 320
SER A 319
THR A 322
 None
 1.03A 4i89A-1cs1A:
0.0		 4i89A-1cs1A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 8 GLY A 365
ASN A 258
PHE A 321
ILE A 362
 None
 0.98A 4j4vC-1cs1A:
0.0		 4j4vC-1cs1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 GLU A 377
TYR A 265
LEU A 266
PHE A 380
 None
 1.38A 4twdF-1cs1A:
0.0
4twdG-1cs1A:
0.0		 4twdF-1cs1A:
21.66
4twdG-1cs1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 GLU A 377
TYR A 265
LEU A 266
PHE A 380
 None
 1.27A 4twdI-1cs1A:
0.0
4twdJ-1cs1A:
0.0		 4twdI-1cs1A:
21.66
4twdJ-1cs1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 LEU A 372
LEU A 320
SER A 319
THR A 322
 None
 1.07A 5bojA-1cs1A:
undetectable		 5bojA-1cs1A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 12 TYR A 199
ASN A 283
HIS A 277
LEU A 376
ILE A 262
 None
 1.26A 5dv4A-1cs1A:
undetectable		 5dv4A-1cs1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 11 PHE A 302
TYR A 265
ILE A 262
ILE A 362
LEU A 318
 None
 0.94A 5e4dB-1cs1A:
1.1		 5e4dB-1cs1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 LEU A 327
TYR A 101
SER A 195
 LLP  A 198 ( 4.6A)
LLP  A 198 ( 3.6A)
LLP  A 198 ( 2.8A)
 0.74A 5iktA-1cs1A:
0.0		 5iktA-1cs1A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 VAL A 154
ARG A 350
PRO A 149
 None
 0.84A 5koxA-1cs1A:
0.0		 5koxA-1cs1A:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 10 GLY A 244
GLY A 202
LEU A  64
THR A 247
ALA A   9
 None
LLP  A 198 ( 3.3A)
None
None
None
 1.05A 5o96G-1cs1A:
undetectable
5o96H-1cs1A:
2.2		 5o96G-1cs1A:
23.14
5o96H-1cs1A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 ASN A 258
THR A 364
ILE A 373
GLU A 370
 None
 1.30A 5uigA-1cs1A:
0.0		 5uigA-1cs1A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 8 GLY A 125
GLU A 127
ILE A 159
GLN A 182
 None
 0.98A 5vlmD-1cs1A:
0.0		 5vlmD-1cs1A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 PHE A  87
ASP A  92
LYS A 139
 None
 0.83A 6awtD-1cs1A:
1.0		 6awtD-1cs1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 9 LEU A 185
VAL A 171
SER A 170
ASP A 173
 None
None
None
LLP  A 198 ( 3.0A)
 0.91A 6c2mD-1cs1A:
0.0		 6c2mD-1cs1A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 9 VAL A 219
LEU A  61
VAL A  56
ASP A  55
 None
 0.98A 6c2mD-1cs1A:
0.0		 6c2mD-1cs1A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		5 / 10 GLY A 244
VAL A 210
VAL A 206
ALA A 208
LEU A  61
 None
 1.08A 6czmA-1cs1A:
0.3
6czmC-1cs1A:
undetectable		 6czmA-1cs1A:
23.23
6czmC-1cs1A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		4 / 6 GLY A 379
ASN A 378
ASP A 375
SER A 319
 None
 1.10A 6dwdA-1cs1A:
0.0
6dwdC-1cs1A:
0.0		 6dwdA-1cs1A:
20.61
6dwdC-1cs1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 ASN A 174
PRO A 179
GLN A   5
 None
 0.88A 6jnhA-1cs1A:
0.0		 6jnhA-1cs1A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)
(Escherichia
coli) 		3 / 3 ASN A 174
PRO A 179
GLN A   5
 None
 0.91A 6jogA-1cs1A:
0.0		 6jogA-1cs1A:
17.99