SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cs6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1cs6 AXONIN-1
(Gallus
gallus) 		3 / 3 GLU A 311
THR A 310
LEU A 359
 None
 0.71A 1v8bC-1cs6A:
undetectable		 1v8bC-1cs6A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1cs6 AXONIN-1
(Gallus
gallus) 		4 / 6 TRP A 123
GLY A 124
THR A 171
VAL A 125
 None
 0.99A 5ewuA-1cs6A:
undetectable		 5ewuA-1cs6A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1cs6 AXONIN-1
(Gallus
gallus) 		4 / 6 TRP A 123
GLY A 124
THR A 171
VAL A 125
 None
 1.14A 5ewuB-1cs6A:
undetectable		 5ewuB-1cs6A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1cs6 AXONIN-1
(Gallus
gallus) 		4 / 8 VAL A 242
PHE A 236
THR A 171
GLY A 155
 None
 0.94A 5v0vA-1cs6A:
undetectable		 5v0vA-1cs6A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1cs6 AXONIN-1
(Gallus
gallus) 		5 / 9 LEU A  33
THR A  20
PRO A  74
PHE A  22
ILE A  71
 None
 1.28A 6ef6A-1cs6A:
undetectable		 6ef6A-1cs6A:
19.75