SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1csy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		3 / 3 LYS A  69
ASP A  45
ASN A  47
 None
 0.94A 2bm9A-1csyA:
undetectable		 2bm9A-1csyA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		4 / 6 VAL A  29
SER A  33
LEU A  61
HIS A  56
 None
 1.26A 2f8dA-1csyA:
0.8		 2f8dA-1csyA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		5 / 10 TYR A  91
ILE A  41
ILE A  65
GLY A  78
LEU A 102
 None
 1.03A 3elzB-1csyA:
0.9		 3elzB-1csyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		5 / 10 TYR A  91
ILE A  41
ILE A  65
GLY A  78
LEU A 102
 None
 1.07A 3elzC-1csyA:
0.0		 3elzC-1csyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		5 / 10 TYR A  91
ILE A  41
ILE A  65
GLY A  78
LEU A 102
 None
 1.00A 3em0A-1csyA:
0.9		 3em0A-1csyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		5 / 12 TYR A  91
ILE A  41
ILE A  65
GLY A  78
LEU A 102
 None
 1.00A 3em0B-1csyA:
0.8		 3em0B-1csyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		4 / 6 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 0.99A 6e43A-1csyA:
0.0		 6e43A-1csyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		4 / 6 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 0.94A 6e43B-1csyA:
0.0		 6e43B-1csyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		4 / 6 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 1.00A 6e43C-1csyA:
0.0		 6e43C-1csyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1csy SYK PROTEIN TYROSINE
KINASE
(Homo
sapiens) 		4 / 6 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 0.92A 6e43D-1csyA:
0.0		 6e43D-1csyA:
15.79