SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ct5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  77
GLU A  69
LEU A 102
 None
 0.77A 1v8bB-1ct5A:
undetectable		 1v8bB-1ct5A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		4 / 5 LEU A  81
PRO A  52
ALA A  53
ILE A   5
 None
 1.02A 2aofB-1ct5A:
undetectable		 2aofB-1ct5A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		5 / 8 LEU A 168
LEU A 177
ILE A 209
VAL A 141
ILE A 114
 None
 1.42A 2uxpA-1ct5A:
undetectable		 2uxpA-1ct5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 127
PRO A 136
SER A 116
ILE A 164
LEU A 177
 None
 1.21A 3iv6C-1ct5A:
undetectable		 3iv6C-1ct5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 237
ALA A 236
ASN A 178
GLU A 112
 None
 1.38A 5dwkC-1ct5A:
undetectable		 5dwkC-1ct5A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1ct5 PROTEIN (YEAST
HYPOTHETICAL
PROTEIN, SELENOMET)
(Saccharomyces
cerevisiae) 		3 / 3 GLY A  93
GLY A  92
GLN A 142
 None
 0.26A 5imsA-1ct5A:
2.3		 5imsA-1ct5A:
17.18