SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ct9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 1a4gA-1ct9A:
undetectable		 1a4gA-1ct9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.41A 1a4gB-1ct9A:
undetectable		 1a4gB-1ct9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ILE A 241
ALA A 244
LEU A 290
LEU A 223
LEU A 345
 None
 1.30A 1g5yB-1ct9A:
undetectable		 1g5yB-1ct9A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ASN A  79
ILE A  77
LEU A 105
GLY A 119
LEU A  83
 None
 1.00A 1liiA-1ct9A:
undetectable		 1liiA-1ct9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 LEU A 331
GLY A 304
VAL A 467
LEU A 464
LEU A 496
 None
 1.36A 1mx1E-1ct9A:
undetectable		 1mx1E-1ct9A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 7 GLY A 349
PHE A 403
PRO A 402
ASP A 405
 IUM  A1102 (-3.8A)
None
None
None
 0.80A 2aouB-1ct9A:
undetectable		 2aouB-1ct9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 LEU A 215
LEU A 432
LYS A 429
GLY A 347
ASP A 238
 None
None
IUM  A1101 ( 3.9A)
AMP  A1100 (-3.7A)
IUM  A1101 ( 3.0A)
 1.16A 2br4E-1ct9A:
undetectable		 2br4E-1ct9A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 THR A 373
ASP A 238
SER A 346
 None
IUM  A1101 ( 3.0A)
AMP  A1100 (-3.0A)
 0.79A 2nxeA-1ct9A:
1.9		 2nxeA-1ct9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 THR A 373
ASP A 238
SER A 346
 None
IUM  A1101 ( 3.0A)
AMP  A1100 (-3.0A)
 0.74A 2nxeB-1ct9A:
2.0		 2nxeB-1ct9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 8 ILE A 102
PHE A 121
LEU A 117
GLY A 136
 None
 0.87A 2vdbA-1ct9A:
0.0		 2vdbA-1ct9A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 ASP A 462
THR A 490
GLU A 493
 None
 0.75A 2zifB-1ct9A:
1.4		 2zifB-1ct9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ILE A 431
ALA A 412
ILE A 241
LEU A 237
ARG A 433
 None
 1.29A 2zzaA-1ct9A:
undetectable		 2zzaA-1ct9A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 9 ARG A  49
ALA A 122
ILE A 142
GLY A 119
ILE A  77
 GLN  A1106 (-3.8A)
None
None
None
None
 1.04A 3el4B-1ct9A:
undetectable		 3el4B-1ct9A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 LEU A 215
GLY A 349
LEU A 358
ILE A 241
SER A 240
 None
IUM  A1102 (-3.8A)
None
None
None
 0.96A 3frqB-1ct9A:
0.0		 3frqB-1ct9A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 PRO A  61
LEU A  62
GLN A  60
 None
 0.67A 3hznG-1ct9A:
0.0
3hznH-1ct9A:
0.0		 3hznG-1ct9A:
17.63
3hznH-1ct9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 SER A 182
ASP A   8
ASP A 127
 None
 0.80A 3iv6A-1ct9A:
2.4		 3iv6A-1ct9A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.39A 4cpnA-1ct9A:
undetectable		 4cpnA-1ct9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.37A 4cpnB-1ct9A:
undetectable		 4cpnB-1ct9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.47A 4cpzA-1ct9A:
undetectable		 4cpzA-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 4cpzB-1ct9A:
undetectable		 4cpzB-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 4cpzC-1ct9A:
undetectable		 4cpzC-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.44A 4cpzD-1ct9A:
undetectable		 4cpzD-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.43A 4cpzE-1ct9A:
undetectable		 4cpzE-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 4cpzF-1ct9A:
undetectable		 4cpzF-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 4cpzG-1ct9A:
undetectable		 4cpzG-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.42A 4cpzH-1ct9A:
undetectable		 4cpzH-1ct9A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 PHE A   7
ALA A  43
LEU A  45
VAL A  70
 None
 0.87A 4dubB-1ct9A:
0.0		 4dubB-1ct9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 TYR A 146
ARG A 137
HIS A 381
 None
 1.21A 4fubA-1ct9A:
0.0		 4fubA-1ct9A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 ARG A 309
ARG A 498
GLU A 499
ALA A 511
GLU A 502
 None
 1.32A 4i00A-1ct9A:
undetectable		 4i00A-1ct9A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 12 PHE A 436
ALA A 438
LEU A 432
PHE A 408
LYS A 248
 None
 1.03A 4kykA-1ct9A:
0.0
4kykB-1ct9A:
0.0		 4kykA-1ct9A:
17.53
4kykB-1ct9A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 SER A  40
TYR A  38
ASP A 131
 None
 0.75A 4rp8C-1ct9A:
0.0		 4rp8C-1ct9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 LEU A 140
ILE A 142
LYS A 406
TYR A 191
 None
 0.90A 4w5nA-1ct9A:
0.0		 4w5nA-1ct9A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ARG A 387
ASP A 384
VAL A 320
ASP A 319
 None
IUM  A1103 (-2.7A)
None
None
 1.03A 4xqeA-1ct9A:
2.1		 4xqeA-1ct9A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ARG A 387
ASP A 384
VAL A 320
ASP A 319
 None
IUM  A1103 (-2.7A)
None
None
 1.03A 4xqeB-1ct9A:
2.3		 4xqeB-1ct9A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 8 ARG A 387
ASP A 384
VAL A 320
ASP A 319
 None
IUM  A1103 (-2.7A)
None
None
 1.04A 4xqgA-1ct9A:
2.4		 4xqgA-1ct9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 8 ARG A 387
ASP A 384
VAL A 320
ASP A 319
 None
IUM  A1103 (-2.7A)
None
None
 1.03A 4xqgB-1ct9A:
1.6		 4xqgB-1ct9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 5 ARG A  28
GLY A  31
GLU A  48
SER A 333
 None
 1.27A 4z3oA-1ct9A:
undetectable
4z3oB-1ct9A:
undetectable		 4z3oA-1ct9A:
22.97
4z3oB-1ct9A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 5 SER A 333
ARG A  28
GLY A  31
GLU A  48
 None
 1.01A 5cdqA-1ct9A:
undetectable
5cdqB-1ct9A:
0.0
5cdqC-1ct9A:
undetectable		 5cdqA-1ct9A:
22.07
5cdqB-1ct9A:
16.43
5cdqC-1ct9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 5 SER A 333
ARG A  28
GLY A  31
GLU A  48
 None
 1.02A 5cdqR-1ct9A:
0.0
5cdqS-1ct9A:
undetectable
5cdqT-1ct9A:
undetectable		 5cdqR-1ct9A:
22.07
5cdqS-1ct9A:
16.43
5cdqT-1ct9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ALA A  72
VAL A  70
TYR A  63
HIS A  47
 None
 0.80A 5eckA-1ct9A:
0.0		 5eckA-1ct9A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ALA A  72
VAL A  70
TYR A  63
HIS A  47
 None
 0.84A 5eckD-1ct9A:
0.0		 5eckD-1ct9A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ALA A  72
VAL A  70
TYR A  63
HIS A  47
 None
 0.81A 5eclA-1ct9A:
undetectable		 5eclA-1ct9A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 6 ALA A  72
VAL A  70
TYR A  63
HIS A  47
 None
 0.87A 5ecoA-1ct9A:
undetectable		 5ecoA-1ct9A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		4 / 4 ALA A 338
PRO A 228
LEU A 267
HIS A 268
 None
 1.48A 5eskA-1ct9A:
0.0		 5eskA-1ct9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 10 ALA A 283
VAL A 286
ILE A 242
VAL A 231
ALA A 271
 None
None
None
None
AMP  A1100 (-3.6A)
 1.09A 5nukA-1ct9A:
0.0		 5nukA-1ct9A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		3 / 3 LYS A   1
LYS A 390
SER A 393
 GLN  A1106 (-4.9A)
None
None
 0.94A 5odiA-1ct9A:
undetectable		 5odiA-1ct9A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 10 TYR A 191
HIS A 139
TYR A 190
ASP A 115
GLY A 119
 None
 1.46A 5zbdA-1ct9A:
0.3		 5zbdA-1ct9A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1ct9 ASPARAGINE
SYNTHETASE B
(Escherichia
coli) 		5 / 10 TYR A 191
HIS A 139
TYR A 190
ASP A 115
GLY A 119
 None
 1.47A 5zbdB-1ct9A:
0.0		 5zbdB-1ct9A:
21.59