SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ctm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		5 / 9 LEU A  75
ALA A  73
LEU A 113
GLU A  34
ALA A  47
 None
 1.45A 1sn0A-1ctmA:
0.0
1sn0C-1ctmA:
0.0		 1sn0A-1ctmA:
18.82
1sn0C-1ctmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1ctm CYTOCHROME F
(Brassica
rapa) 		4 / 8 ILE A 115
GLY A 152
CYH A  21
HIS A  25
 None
None
HEM  A 253 (-1.8A)
HEM  A 253 (-3.1A)
 0.83A 1sv9A-1ctmA:
undetectable		 1sv9A-1ctmA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		3 / 3 GLN A 158
HIS A  25
ARG A 154
 None
HEM  A 253 (-3.1A)
None
 0.77A 1zlqA-1ctmA:
0.0		 1zlqA-1ctmA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 1ctm CYTOCHROME F
(Brassica
rapa) 		4 / 7 GLY A 235
GLY A 234
VAL A  31
SER A  28
 None
 0.67A 2oa1B-1ctmA:
undetectable		 2oa1B-1ctmA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1ctm CYTOCHROME F
(Brassica
rapa) 		5 / 7 VAL A  31
ILE A  51
ALA A  73
VAL A 150
GLY A 237
 None
 1.39A 2xrzB-1ctmA:
undetectable		 2xrzB-1ctmA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		4 / 7 LEU A  75
ALA A  73
LEU A 113
VAL A  71
 None
None
None
HEM  A 253 (-4.9A)
 0.97A 3d2tA-1ctmA:
0.0		 3d2tA-1ctmA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		3 / 3 TYR A 190
LEU A 223
LYS A 222
 None
 0.74A 3sueD-1ctmA:
0.0		 3sueD-1ctmA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1ctm CYTOCHROME F
(Brassica
rapa) 		3 / 3 LYS A 109
TYR A 105
ARG A 106
 None
 1.22A 4gc9A-1ctmA:
undetectable		 4gc9A-1ctmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		4 / 5 LEU A  75
ALA A  73
LEU A 113
VAL A  71
 None
None
None
HEM  A 253 (-4.9A)
 0.89A 5cr1A-1ctmA:
0.0		 5cr1A-1ctmA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1ctm CYTOCHROME F
(Brassica
rapa) 		4 / 6 GLY A  80
GLU A  79
TYR A 146
ILE A 243
 None
 0.67A 5kmfA-1ctmA:
undetectable
5kmfC-1ctmA:
undetectable		 5kmfA-1ctmA:
21.09
5kmfC-1ctmA:
21.09