SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ctt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 LEU A 215
LEU A 247
MET A  90
ARG A   4
LEU A 283
None
1.40A 1a28B-1cttA:
undetectable
1a28B-1cttA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 GLY A 242
LEU A 215
PHE A  92
THR A 279
LEU A 280
None
1.27A 1a8uA-1cttA:
undetectable
1a8uA-1cttA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 GLY A 242
LEU A 215
PHE A  92
THR A 279
LEU A 280
None
1.30A 1a8uB-1cttA:
undetectable
1a8uB-1cttA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 SER A 106
LEU A 249
ILE A 108
ALA A 111
SER A 114
None
1.15A 1eqgB-1cttA:
0.0
1eqgB-1cttA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 7 LEU A  59
PHE A  86
LEU A  24
SER A  40
None
0.84A 1wrlE-1cttA:
0.0
1wrlF-1cttA:
undetectable
1wrlE-1cttA:
15.73
1wrlF-1cttA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 LEU A 161
PHE A 165
ALA A 232
ALA A 231
GLU A 138
None
1.32A 1wygA-1cttA:
0.0
1wygA-1cttA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 LEU A 280
LEU A 244
ASP A 189
ALA A 214
ALA A 195
None
1.09A 2br4F-1cttA:
undetectable
2br4F-1cttA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 ALA A  61
ALA A  88
LEU A 249
ALA A  31
LEU A  57
None
0.95A 2bxgB-1cttA:
undetectable
2bxgB-1cttA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 LEU A 215
LEU A 247
MET A  90
ARG A   4
LEU A 283
None
1.44A 2w8yB-1cttA:
undetectable
2w8yB-1cttA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 ILE A  76
ALA A  55
LEU A  12
LEU A  41
PHE A  86
None
1.07A 2w9sD-1cttA:
undetectable
2w9sD-1cttA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 ILE A  76
ALA A  55
LEU A  12
LEU A  41
PHE A  86
None
1.09A 2w9sF-1cttA:
undetectable
2w9sF-1cttA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 PRO A  58
ALA A  61
ALA A  19
THR A  45
LEU A  52
None
1.30A 2x2nB-1cttA:
0.0
2x2nB-1cttA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 4 ARG A  78
GLY A  82
GLU A  49
SER A 114
None
1.36A 2xctS-1cttA:
undetectable
2xctU-1cttA:
undetectable
2xctS-1cttA:
16.88
2xctU-1cttA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 8 MET A  90
LEU A 280
ILE A 257
LEU A 283
LEU A 240
None
1.50A 2xfhA-1cttA:
0.0
2xfhA-1cttA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 9 ARG A  78
THR A 123
VAL A 124
LEU A 149
ALA A 154
None
1.43A 3ax7B-1cttA:
0.0
3ax7B-1cttA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 8 THR A  83
LEU A  32
ALA A 111
SER A 114
None
0.94A 3kp6A-1cttA:
0.0
3kp6A-1cttA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 ARG A 133
ALA A 107
GLY A  74
VAL A  73
ILE A 122
None
None
None
DHZ  A 295 (-4.5A)
None
0.96A 3oxxD-1cttA:
undetectable
3oxxD-1cttA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 GLY A 225
GLY A 212
LEU A 237
SER A 109
ALA A 243
None
1.25A 3sxjA-1cttA:
undetectable
3sxjA-1cttA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 GLY A 225
GLY A 212
LEU A 237
SER A 109
ALA A 243
None
1.25A 3sxjB-1cttA:
undetectable
3sxjB-1cttA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 12 LEU A 237
SER A 211
VAL A 101
ALA A 195
LEU A 283
None
1.29A 4nc3A-1cttA:
undetectable
4nc3A-1cttA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  52
LEU A  56
LYS A  42
LEU A  41
LEU A  33
None
0.98A 4wg0B-1cttA:
undetectable
4wg0C-1cttA:
undetectable
4wg0D-1cttA:
undetectable
4wg0B-1cttA:
6.47
4wg0C-1cttA:
6.47
4wg0D-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  52
LEU A  56
LYS A  42
LEU A  41
LEU A  33
None
0.98A 4wg0D-1cttA:
undetectable
4wg0E-1cttA:
undetectable
4wg0F-1cttA:
undetectable
4wg0D-1cttA:
6.47
4wg0E-1cttA:
6.47
4wg0F-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  16
GLU A  21
LEU A  20
LEU A  59
LEU A  56
None
1.01A 4wg0C-1cttA:
undetectable
4wg0D-1cttA:
undetectable
4wg0E-1cttA:
undetectable
4wg0C-1cttA:
6.47
4wg0D-1cttA:
6.47
4wg0E-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  52
LEU A  56
LYS A  42
LEU A  41
LEU A  33
None
0.96A 4wg0F-1cttA:
undetectable
4wg0G-1cttA:
undetectable
4wg0H-1cttA:
undetectable
4wg0F-1cttA:
6.47
4wg0G-1cttA:
6.47
4wg0H-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  52
LEU A  56
LYS A  42
LEU A  41
LEU A  33
None
1.01A 4wg0H-1cttA:
undetectable
4wg0I-1cttA:
undetectable
4wg0J-1cttA:
undetectable
4wg0H-1cttA:
6.47
4wg0I-1cttA:
6.47
4wg0J-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  33
LYS A  42
LEU A  41
LEU A  52
LEU A  56
None
0.98A 4wg0G-1cttA:
undetectable
4wg0H-1cttA:
undetectable
4wg0I-1cttA:
undetectable
4wg0G-1cttA:
6.47
4wg0H-1cttA:
6.47
4wg0I-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  52
LEU A  56
LYS A  42
LEU A  41
LEU A  33
None
1.01A 4wg0J-1cttA:
undetectable
4wg0K-1cttA:
undetectable
4wg0L-1cttA:
undetectable
4wg0J-1cttA:
6.47
4wg0K-1cttA:
6.47
4wg0L-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  33
LYS A  42
LEU A  41
LEU A  52
LEU A  56
None
1.03A 4wg0I-1cttA:
undetectable
4wg0J-1cttA:
undetectable
4wg0K-1cttA:
undetectable
4wg0I-1cttA:
6.47
4wg0J-1cttA:
6.47
4wg0K-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 11 LEU A  33
LYS A  42
LEU A  41
LEU A  52
LEU A  56
None
0.99A 4wg0K-1cttA:
undetectable
4wg0L-1cttA:
undetectable
4wg0M-1cttA:
undetectable
4wg0K-1cttA:
6.47
4wg0L-1cttA:
6.47
4wg0M-1cttA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 9 SER A 109
ALA A 111
LEU A 139
LEU A 145
None
0.94A 4xtaA-1cttA:
undetectable
4xtaA-1cttA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 4 GLN A  99
THR A 276
LEU A 247
LEU A 244
None
1.15A 5m5kB-1cttA:
undetectable
5m5kB-1cttA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
5 / 10 ILE A  76
GLY A  82
GLY A  79
LEU A  52
VAL A  38
None
1.15A 5twjB-1cttA:
undetectable
5twjB-1cttA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 5 HIS A 182
ALA A 199
SER A 202
TYR A 227
None
1.41A 5yodF-1cttA:
0.0
5yodF-1cttA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)
1ctt CYTIDINE DEAMINASE
(Escherichia
coli)
4 / 6 SER A 226
ALA A 214
SER A 224
ALA A 263
None
0.78A 6bocA-1cttA:
undetectable
6bocB-1cttA:
undetectable
6bocC-1cttA:
undetectable
6bocD-1cttA:
undetectable
6bocA-1cttA:
6.80
6bocB-1cttA:
6.80
6bocC-1cttA:
6.80
6bocD-1cttA:
6.80