SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		5 / 12 MET B 972
ALA B 946
ILE B 919
ILE B 918
LEU B 926
 None
 1.32A 2bjfA-1culB:
0.0		 2bjfA-1culB:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		5 / 11 GLY B 933
SER B 951
THR B 948
GLY B 949
HIS B 968
 None
 1.35A 2hmaA-1culB:
undetectable		 2hmaA-1culB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		5 / 8 LEU B 979
ILE B 918
GLY B 941
ILE B 940
LEU B 996
 None
None
None
103  B1082 (-4.9A)
None
 1.13A 2o4nB-1culB:
0.0		 2o4nB-1culB:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		3 / 3 THR B1042
ASN B1001
GLU B1044
 None
 0.72A 3v4tA-1culB:
0.0
3v4tC-1culB:
0.0		 3v4tA-1culB:
21.09
3v4tC-1culB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		4 / 7 TYR B1073
GLY B1060
ARG B1059
LYS B1071
 None
 0.97A 4fgzA-1culB:
undetectable		 4fgzA-1culB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1cul TYPE II ADENYLYL
CYCLASE
(Rattus
norvegicus) 		4 / 6 GLY B1008
GLN B 880
TYR B 882
TYR B1017
 None
 1.29A 6ag0C-1culB:
undetectable		 6ag0C-1culB:
17.86