SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1cun PROTEIN (ALPHA
SPECTRIN)
(Gallus
gallus) 		4 / 5 ILE A 147
SER A 137
LEU A 214
ASN A 217
 None
 1.11A 1y0xX-1cunA:
undetectable		 1y0xX-1cunA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 1cun PROTEIN (ALPHA
SPECTRIN)
(Gallus
gallus) 		5 / 12 ALA A 119
GLU A 113
ILE A 189
VAL A 171
CYH A 172
 None
 1.19A 5vlmB-1cunA:
2.1		 5vlmB-1cunA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1cun PROTEIN (ALPHA
SPECTRIN)
(Gallus
gallus) 		4 / 5 LEU A  97
LYS A  25
LEU A  55
GLU A  54
 None
 0.99A 5weaA-1cunA:
undetectable		 5weaA-1cunA:
13.62