SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 ARG A 112
ASP A 248
ASP A 281
GLY A  89
THR A 337
 None
None
H37  A 501 ( 4.7A)
None
None
 1.05A 1c6zA-1cvrA:
undetectable		 1c6zA-1cvrA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.10A 1q23B-1cvrA:
0.0		 1q23B-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.10A 1q23C-1cvrA:
0.0		 1q23C-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 10 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.10A 1q23E-1cvrA:
0.0		 1q23E-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.08A 1q23F-1cvrA:
0.0		 1q23F-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.10A 1q23H-1cvrA:
0.3
1q23I-1cvrA:
0.0		 1q23H-1cvrA:
19.55
1q23I-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.14A 1q23I-1cvrA:
0.0		 1q23I-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 10 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.12A 1q23K-1cvrA:
0.0		 1q23K-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 ALA A 358
LEU A 415
ALA A 380
LEU A 382
VAL A 394
 None
 1.06A 1sn5B-1cvrA:
undetectable
1sn5D-1cvrA:
0.0		 1sn5B-1cvrA:
14.67
1sn5D-1cvrA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 PHE A 310
ASN A 207
TYR A 179
SER A 204
ASP A 292
 None
None
None
None
CA  A 502 (-2.5A)
 1.37A 2iyfB-1cvrA:
4.1		 2iyfB-1cvrA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		3 / 3 TYR A  72
GLY A 111
PHE A 109
 None
 0.70A 2m2pB-1cvrA:
undetectable		 2m2pB-1cvrA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA156_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 7 GLU A 132
THR A 128
MET A  12
LEU A  36
 None
 1.14A 2rezA-1cvrA:
0.0		 2rezA-1cvrA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 7 SER A 220
TYR A 208
VAL A 206
ILE A 195
 None
 0.92A 3bu1A-1cvrA:
undetectable		 3bu1A-1cvrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 LEU A 260
LEU A 146
GLY A 201
VAL A 190
ILE A 148
 None
 1.07A 3c6gA-1cvrA:
0.0		 3c6gA-1cvrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 LEU A 260
LEU A 146
GLY A 202
VAL A 190
ILE A 148
 None
 0.97A 3c6gA-1cvrA:
0.0		 3c6gA-1cvrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 5 ASN A 172
ALA A 145
LEU A 349
GLY A 178
 None
 0.94A 3dl9A-1cvrA:
0.0		 3dl9A-1cvrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 ALA A 366
ASN A 404
LEU A 403
LEU A 413
VAL A 431
 None
 1.12A 3fl9B-1cvrA:
undetectable		 3fl9B-1cvrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 6 PHE A 256
HIS A 226
THR A 224
VAL A 227
 None
 1.19A 3lb3A-1cvrA:
0.0		 3lb3A-1cvrA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 10 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.13A 3u9fI-1cvrA:
0.0		 3u9fI-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.15A 3u9fJ-1cvrA:
0.0
3u9fK-1cvrA:
0.0		 3u9fJ-1cvrA:
19.55
3u9fK-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 10 TYR A 131
PHE A 310
LEU A 298
PHE A 240
VAL A 313
 None
 1.11A 3u9fR-1cvrA:
0.0		 3u9fR-1cvrA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 6 CYH A 255
ASN A 246
GLY A 247
ASP A 248
 None
 1.11A 3w9tE-1cvrA:
0.0		 3w9tE-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 6 CYH A 255
THR A 215
GLY A 247
ASP A 248
 None
 1.15A 3w9tE-1cvrA:
0.0		 3w9tE-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 VAL A  14
VAL A  76
PHE A 113
ILE A 125
 None
 0.61A 3warA-1cvrA:
undetectable		 3warA-1cvrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 7 GLY A 317
ASP A 292
GLY A 290
HIS A 166
 None
CA  A 502 (-2.5A)
None
CA  A 502 (-3.2A)
 0.86A 4c5nA-1cvrA:
2.9		 4c5nA-1cvrA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 ALA A 277
GLY A 247
GLU A 258
GLY A 223
TRP A 217
 None
None
CA  A 503 (-2.3A)
None
None
 1.24A 4e47A-1cvrA:
undetectable		 4e47A-1cvrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 ALA A 277
GLY A 247
GLU A 258
GLY A 223
TRP A 217
 None
None
CA  A 503 (-2.3A)
None
None
 1.26A 4e47B-1cvrA:
undetectable		 4e47B-1cvrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 LEU A 415
ALA A 380
LEU A 382
VAL A 394
 None
 0.92A 4iizB-1cvrA:
5.5		 4iizB-1cvrA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 ALA A 277
GLY A 247
GLU A 258
GLY A 223
TRP A 217
 None
None
CA  A 503 (-2.3A)
None
None
 1.27A 4jdsA-1cvrA:
undetectable		 4jdsA-1cvrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 11 ALA A 277
GLY A 247
GLU A 258
GLY A 223
TRP A 217
 None
None
CA  A 503 (-2.3A)
None
None
 1.27A 4jdsB-1cvrA:
undetectable		 4jdsB-1cvrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 GLU A 132
MET A 315
VAL A 313
THR A 314
 None
 1.11A 4lnwA-1cvrA:
0.0		 4lnwA-1cvrA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 PRO A 237
PHE A 256
VAL A 206
GLY A 210
THR A 219
 None
None
None
H37  A 501 (-3.5A)
None
 1.46A 4mubA-1cvrA:
undetectable		 4mubA-1cvrA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 4 ASN A 106
GLY A  97
ASP A 248
ASP A 334
 None
 1.40A 4n49A-1cvrA:
1.6		 4n49A-1cvrA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		3 / 3 THR A 123
HIS A 226
LEU A 230
 None
 0.75A 5axdA-1cvrA:
4.3		 5axdA-1cvrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		3 / 3 THR A 123
HIS A 226
LEU A 230
 None
 0.75A 5axdC-1cvrA:
4.3		 5axdC-1cvrA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DL9_A_ACTA214_0
(LYSOZYME C)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 5 GLU A  44
ASP A  45
VAL A  16
ALA A  17
 None
 1.33A 5dl9A-1cvrA:
undetectable		 5dl9A-1cvrA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 ALA A 145
LEU A 205
TYR A 208
ILE A 148
LEU A 260
 None
 1.00A 5ljcA-1cvrA:
undetectable		 5ljcA-1cvrA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 8 VAL A 108
LEU A  70
ILE A  13
ILE A  15
SER A  92
 None
 1.45A 5numA-1cvrA:
0.1		 5numA-1cvrA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 GLU A  21
LEU A  75
ILE A  46
ALA A  43
GLU A  44
 None
 1.19A 5v0vA-1cvrA:
undetectable		 5v0vA-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 SER A 220
ILE A 195
PHE A 256
ALA A 216
GLU A 167
 None
 1.21A 5vcgA-1cvrA:
0.0		 5vcgA-1cvrA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 9 THR A 279
GLY A 247
ALA A 277
CYH A 255
LEU A 250
 None
 1.07A 5vw4A-1cvrA:
undetectable		 5vw4A-1cvrA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 VAL A  14
VAL A  76
PHE A 113
ILE A 125
 None
 0.79A 5y9mA-1cvrA:
undetectable		 5y9mA-1cvrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 VAL A  14
VAL A  76
PHE A 113
ILE A 125
 None
 0.70A 5y9mX-1cvrA:
undetectable		 5y9mX-1cvrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 7 VAL A  14
VAL A  76
PHE A 113
ILE A 125
 None
 0.73A 5yf9B-1cvrA:
undetectable		 5yf9B-1cvrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		5 / 12 LEU A 345
GLY A  35
ARG A  11
TYR A  72
PRO A 342
 None
 1.13A 6ce2B-1cvrA:
undetectable		 6ce2B-1cvrA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 6 SER A 252
ASP A  78
GLU A 258
THR A 224
 None
CA  A 503 (-2.1A)
CA  A 503 (-2.3A)
None
 1.47A 6djzA-1cvrA:
undetectable		 6djzA-1cvrA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 5 PHE A  27
VAL A 418
MET A  12
VAL A  28
 None
 0.93A 6ekzA-1cvrA:
0.0		 6ekzA-1cvrA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1cvr GINGIPAIN R
(Porphyromonas
gingivalis) 		4 / 8 PHE A 222
PHE A 256
VAL A 206
TYR A 208
 None
 1.06A 6huoC-1cvrA:
1.2
6huoD-1cvrA:
1.4		 6huoC-1cvrA:
10.50
6huoD-1cvrA:
10.84