SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1cwp COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		3 / 3 TRP A  94
ALA A 136
VAL A 134
 None
 0.83A 1bdwA-1cwpA:
undetectable
1bdwB-1cwpA:
undetectable		 1bdwA-1cwpA:
11.46
1bdwB-1cwpA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1cwp COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		3 / 3 THR A 146
LEU A  86
VAL A 178
 None
 0.68A 1mz9E-1cwpA:
undetectable		 1mz9E-1cwpA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 1cwp COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		4 / 7 SER A 130
ASP A 128
SER A 160
LEU A  97
 None
 1.11A 2cdqB-1cwpA:
undetectable		 2cdqB-1cwpA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1cwp COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		4 / 8 LEU A  93
LEU A 173
VAL A 171
ILE A  70
 None
 0.71A 4oj4A-1cwpA:
0.0		 4oj4A-1cwpA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1cwp COAT PROTEIN
(Cowpea
chlorotic
mottle
virus) 		4 / 8 ILE A  70
LEU A 147
LEU A 154
ILE A 145
 None
 0.83A 4r38D-1cwpA:
0.0		 4r38D-1cwpA:
19.29