SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 7 TRP A 936
ILE A 858
LEU A 932
TRP A 889
 None
 1.15A 1q0yH-1cwvA:
6.1
1q0yL-1cwvA:
6.5		 1q0yH-1cwvA:
18.11
1q0yL-1cwvA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 6 ARG A 926
GLY A 934
LYS A 816
THR A 817
 None
 1.11A 2m2oB-1cwvA:
undetectable		 2m2oB-1cwvA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 6 ARG A 926
PRO A 815
LYS A 816
THR A 817
 None
 1.24A 2m2oB-1cwvA:
undetectable		 2m2oB-1cwvA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 7 VAL A 577
VAL A 509
ASP A 512
VAL A 524
 None
 0.99A 2qbnA-1cwvA:
0.0		 2qbnA-1cwvA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 6 VAL A 577
ASP A 512
HIS A 592
ASN A 546
 None
 1.34A 2zs9A-1cwvA:
undetectable		 2zs9A-1cwvA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		5 / 12 ALA A 637
VAL A 675
TYR A 659
ASN A 638
ILE A 598
 None
 1.50A 3a65A-1cwvA:
undetectable		 3a65A-1cwvA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		5 / 12 ILE A 750
LEU A 721
GLY A 715
GLY A 766
ASN A 767
 None
 0.90A 3uq6A-1cwvA:
undetectable		 3uq6A-1cwvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		5 / 12 ILE A 750
LEU A 721
GLY A 715
GLY A 766
ASN A 767
 None
 0.88A 3vaqA-1cwvA:
undetectable		 3vaqA-1cwvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		5 / 12 ILE A 750
LEU A 721
GLY A 715
GLY A 766
ASN A 767
 None
 0.89A 3vasA-1cwvA:
undetectable		 3vasA-1cwvA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 6 TYR A 942
THR A 823
ARG A 926
PHE A 814
 None
 1.49A 4kf9A-1cwvA:
0.0		 4kf9A-1cwvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 8 PRO A 697
PHE A 723
LEU A 739
PHE A 732
 None
 0.95A 4qopC-1cwvA:
undetectable		 4qopC-1cwvA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		4 / 5 ALA A 671
VAL A 673
PHE A 691
ILE A 622
 None
 1.04A 5of1B-1cwvA:
0.0		 5of1B-1cwvA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 1cwv INVASIN
(Yersinia
pseudotuberculos
is) 		5 / 12 PHE A 641
ILE A 651
THR A 672
ALA A 637
ALA A 680
 None
 1.25A 5vcgA-1cwvA:
0.0		 5vcgA-1cwvA:
21.66