SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cx1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 ALA A 136
GLY A  44
GLY A  43
GLY A  98
PRO A  79
 None
 1.04A 1sqfA-1cx1A:
undetectable		 1sqfA-1cx1A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 LEU A  68
ILE A 143
MET A  37
PHE A  15
PHE A 131
 None
 1.34A 1xomA-1cx1A:
undetectable		 1xomA-1cx1A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 12 LEU A  68
ILE A 143
MET A  37
PHE A  15
PHE A 131
 None
 1.33A 1xomB-1cx1A:
undetectable		 1xomB-1cx1A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H9T_H_SVRH301_1
(THROMBIN)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		5 / 11 PRO A  21
TRP A  22
VAL A 146
GLN A 145
GLU A 105
 None
 1.44A 2h9tH-1cx1A:
undetectable		 2h9tH-1cx1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 7 GLY A  85
GLY A  61
PHE A  70
PHE A 131
 None
 0.93A 3ko0M-1cx1A:
undetectable
3ko0P-1cx1A:
undetectable		 3ko0M-1cx1A:
17.61
3ko0P-1cx1A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 8 GLU A  64
THR A 150
ALA A 152
VAL A   7
 None
 0.76A 4iizB-1cx1A:
1.0		 4iizB-1cx1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1cx1 ENDOGLUCANASE C
(Cellulomonas
fimi) 		4 / 8 GLU A  64
THR A 150
ALA A 152
VAL A   7
 None
 0.77A 4ik6B-1cx1A:
0.0		 4ik6B-1cx1A:
23.08