SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1cxz PROTEIN (PKN)
(Homo
sapiens) 		4 / 7 LEU B  70
LEU B  59
LEU B  66
GLY B  67
 None
 0.86A 1n13D-1cxzB:
undetectable
1n13E-1cxzB:
undetectable		 1n13D-1cxzB:
20.00
1n13E-1cxzB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1cxz PROTEIN (PKN)
(Homo
sapiens) 		4 / 7 LEU B  42
LEU B  87
LEU B  94
GLU B  93
 None
 0.93A 2vq5B-1cxzB:
undetectable		 2vq5B-1cxzB:
16.42