SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1cyq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 CYH A  41
CYH A 100
HIS A 110
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.2A)
 0.32A 2iwkA-1cyqA:
0.0		 2iwkA-1cyqA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 CYH A  41
CYH A 100
HIS A 110
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.2A)
 0.36A 2iwkB-1cyqA:
0.0		 2iwkB-1cyqA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		4 / 5 SER A  77
HIS A 106
ARG A  61
LEU A 111
 None
 1.18A 2qhfA-1cyqA:
0.0		 2qhfA-1cyqA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 CYH A  41
CYH A 100
HIS A 110
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.2A)
 0.38A 3dtuB-1cyqA:
0.0		 3dtuB-1cyqA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 CYH A  41
CYH A 100
HIS A 110
 ZN  A 602 (-2.3A)
ZN  A 602 (-2.3A)
ZN  A 602 (-3.2A)
 0.37A 3dtuD-1cyqA:
0.0		 3dtuD-1cyqA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		5 / 12 GLY A  20
ILE A  44
GLY A  51
VAL A  52
VAL A  80
 None
 0.88A 3nu5A-1cyqA:
0.0		 3nu5A-1cyqA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 SER A 159
GLY A 158
GLN A 156
 None
 0.35A 3v4tH-1cyqA:
0.0		 3v4tH-1cyqA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		4 / 7 GLU A  16
ILE A  12
VAL A 136
PHE A  82
 None
 0.97A 4a97H-1cyqA:
undetectable		 4a97H-1cyqA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 HIS A  78
VAL A 136
LEU A  99
 None
 0.69A 4m2vA-1cyqA:
0.0		 4m2vA-1cyqA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1cyq INTRON-ENCODED
HOMING ENDONUCLEASE
I-PPOI
(Physarum
polycephalum) 		3 / 3 GLY A  34
GLY A  33
GLN A 141
 None
 0.38A 5imsA-1cyqA:
undetectable		 5imsA-1cyqA:
13.20