SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1czi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 8 PHE E  56
GLY E 102
VAL E 136
PHE E  27
 None
 1.02A 1gsfC-1cziE:
0.0		 1gsfC-1cziE:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.83A 1hpvA-1cziE:
6.9		 1hpvA-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.83A 1hsgB-1cziE:
6.9		 1hsgB-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.84A 1muiA-1cziE:
6.8		 1muiA-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 1rl8A-1cziE:
6.6		 1rl8A-1cziE:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.69A 1rl8B-1cziE:
6.4		 1rl8B-1cziE:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.86A 1sdvB-1cziE:
6.8		 1sdvB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  20
GLY E 119
LEU E  71
GLY E  82
PRO E  58
 None
 1.09A 1y4lA-1cziE:
undetectable		 1y4lA-1cziE:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 5 ASP E 303
GLY E  34
VAL E 153
ILE E 306
 None
 0.91A 2aoiA-1cziE:
6.8		 2aoiA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.83A 2avoB-1cziE:
7.1		 2avoB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.68A 2avsA-1cziE:
6.9		 2avsA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.49A 2avsA-1cziE:
6.9		 2avsA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.54A 2avvA-1cziE:
6.8		 2avvA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.62A 2avvB-1cziE:
6.7		 2avvB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.51A 2avvD-1cziE:
6.6		 2avvD-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 2avvE-1cziE:
6.5		 2avvE-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 2bpxB-1cziE:
6.3		 2bpxB-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.78A 2f81A-1cziE:
6.8		 2f81A-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 2f81A-1cziE:
6.8		 2f81A-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.75A 2f81B-1cziE:
6.7		 2f81B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.59A 2f81B-1cziE:
6.7		 2f81B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.60A 2f8gA-1cziE:
6.8		 2f8gA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 2f8gB-1cziE:
6.7		 2f8gB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.57A 2hs2B-1cziE:
6.7		 2hs2B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.70A 2idwB-1cziE:
6.9		 2idwB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.80A 2ienA-1cziE:
6.7		 2ienA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.64A 2ienA-1cziE:
6.7		 2ienA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.53A 2nmyB-1cziE:
6.4		 2nmyB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.47A 2nmzA-1cziE:
6.8		 2nmzA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.57A 2nmzB-1cziE:
6.8		 2nmzB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.70A 2o4kB-1cziE:
6.7		 2o4kB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.54A 2o4lB-1cziE:
6.8		 2o4lB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 8 LEU E 165
GLY E 119
ILE E 120
LEU E   6
 None
 0.78A 2o4nB-1cziE:
6.8		 2o4nB-1cziE:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.79A 2q63A-1cziE:
6.6		 2q63A-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.80A 2q64B-1cziE:
6.8		 2q64B-1cziE:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 2qakA-1cziE:
6.7		 2qakA-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.88A 2r5pB-1cziE:
7.0		 2r5pB-1cziE:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E  32
GLY E  34
ASP E  37
ILE E  73
ILE E 120
 None
 0.89A 2r5qB-1cziE:
6.9		 2r5qB-1cziE:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E  32
GLY E  34
ASP E  37
ILE E  73
ILE E 120
 None
 0.89A 2r5qD-1cziE:
6.9		 2r5qD-1cziE:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.56A 2rkfA-1cziE:
6.9		 2rkfA-1cziE:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 2rkfB-1cziE:
6.9		 2rkfB-1cziE:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.56A 2rkgA-1cziE:
6.9		 2rkgA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 2rkgB-1cziE:
6.9		 2rkgB-1cziE:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
ASP E  32
GLY E  34
SER E  36
 None
 0.87A 2v0zC-1cziE:
43.6		 2v0zC-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		9 / 12 GLN E  13
ASP E  32
GLY E  34
SER E  35
TYR E  75
PHE E 117
ASP E 215
GLY E 217
SER E 219
 None
 0.62A 2v0zC-1cziE:
43.6		 2v0zC-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 GLN E 188
ASP E 215
GLY E 217
ASP E  32
GLY E  34
 None
 0.66A 2v0zC-1cziE:
43.6		 2v0zC-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
ASP E  32
GLY E  34
SER E  36
 None
 0.87A 2v0zO-1cziE:
44.5		 2v0zO-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		8 / 12 GLN E  13
ASP E  32
GLY E  34
ALA E 115
PHE E 117
ASP E 215
GLY E 217
SER E 219
 None
 0.62A 2v0zO-1cziE:
44.5		 2v0zO-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_O_C41O1327_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 GLN E 188
ASP E 215
GLY E 217
ASP E  32
GLY E  34
 None
 0.67A 2v0zO-1cziE:
44.5		 2v0zO-1cziE:
36.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.85A 2z54B-1cziE:
6.8		 2z54B-1cziE:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 6 GLY E 223
GLU E 289
ILE E 300
ASP E 227
 None
 0.98A 3a7eA-1cziE:
undetectable		 3a7eA-1cziE:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 GLY E 217
ASP E 303
SER E  12
 None
 0.55A 3brfA-1cziE:
undetectable		 3brfA-1cziE:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 5 LEU E  30
ASP E  32
ILE E 120
GLY E 217
 None
 0.46A 3bufA-1cziE:
10.8		 3bufA-1cziE:
28.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.67A 3cywA-1cziE:
6.8		 3cywA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 3cywB-1cziE:
6.7		 3cywB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 3cyxA-1cziE:
6.8		 3cyxA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.43A 3d1xB-1cziE:
6.8		 3d1xB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.64A 3d1zB-1cziE:
6.7		 3d1zB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 3d20A-1cziE:
6.7		 3d20A-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 3d20B-1cziE:
6.6		 3d20B-1cziE:
17.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
LEU E  30
ASP E  32
SER E  36
 None
 0.83A 3d91A-1cziE:
43.8		 3d91A-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		7 / 12 GLN E  13
ASP E  32
GLY E  34
THR E  77
PHE E 117
ASP E 215
SER E 219
 None
 0.71A 3d91A-1cziE:
43.8		 3d91A-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 GLN E 188
ASP E 215
GLY E 217
LEU E  30
ASP E  32
 None
 0.64A 3d91A-1cziE:
43.8		 3d91A-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
LEU E  30
ASP E  32
SER E  36
 None
 0.86A 3d91B-1cziE:
43.1		 3d91B-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 GLN E  13
ASP E  32
GLY E  34
THR E  77
ASP E 215
SER E 219
 None
 0.64A 3d91B-1cziE:
43.1		 3d91B-1cziE:
36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 GLN E 188
ASP E 215
GLY E 217
LEU E  30
ASP E  32
 None
 0.75A 3d91B-1cziE:
43.1		 3d91B-1cziE:
36.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 8 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.79A 3ekpA-1cziE:
6.4		 3ekpA-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.75A 3ekpD-1cziE:
6.4		 3ekpD-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.73A 3ekpD-1cziE:
6.4		 3ekpD-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.76A 3ektC-1cziE:
6.4		 3ektC-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.70A 3ektC-1cziE:
6.4		 3ektC-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.83A 3ekvA-1cziE:
6.3		 3ekvA-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.65A 3ekvA-1cziE:
6.3		 3ekvA-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.76A 3ekxA-1cziE:
6.6		 3ekxA-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 8 ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 3el0A-1cziE:
6.1		 3el0A-1cziE:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 3el1B-1cziE:
6.1		 3el1B-1cziE:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.75A 3em3A-1cziE:
6.8		 3em3A-1cziE:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.61A 3em3A-1cziE:
6.8		 3em3A-1cziE:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.84A 3jw2A-1cziE:
6.9		 3jw2A-1cziE:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.78A 3jw2A-1cziE:
6.9		 3jw2A-1cziE:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.80A 3jw2B-1cziE:
6.6		 3jw2B-1cziE:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.65A 3jw2B-1cziE:
6.6		 3jw2B-1cziE:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 GLU E 107
GLY E 119
GLY E  82
SER E 104
PHE E  56
 None
 1.19A 3k13C-1cziE:
undetectable		 3k13C-1cziE:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.50A 3k4vA-1cziE:
6.9		 3k4vA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.76A 3k4vB-1cziE:
6.8		 3k4vB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.46A 3k4vB-1cziE:
6.8		 3k4vB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.57A 3k4vD-1cziE:
6.9		 3k4vD-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 8 LEU E 301
VAL E 197
ILE E 231
VAL E 258
LEU E 269
 None
 1.28A 3kp6A-1cziE:
0.0
3kp6B-1cziE:
undetectable		 3kp6A-1cziE:
17.87
3kp6B-1cziE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.66A 3lzuA-1cziE:
6.8		 3lzuA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.78A 3lzuB-1cziE:
6.6		 3lzuB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.83A 3lzuB-1cziE:
6.6		 3lzuB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.68A 3mwsA-1cziE:
7.1		 3mwsA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 3ndtA-1cziE:
6.7		 3ndtA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.50A 3ndtB-1cziE:
7.0		 3ndtB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.47A 3ndtC-1cziE:
6.6		 3ndtC-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.80A 3ndtD-1cziE:
6.8		 3ndtD-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.52A 3ndtD-1cziE:
6.8		 3ndtD-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.51A 3nduA-1cziE:
6.7		 3nduA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.47A 3nduB-1cziE:
6.9		 3nduB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.46A 3nduC-1cziE:
6.9		 3nduC-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.56A 3nduD-1cziE:
6.4		 3nduD-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.71A 3nu3A-1cziE:
6.8		 3nu3A-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.73A 3nu3B-1cziE:
6.7		 3nu3B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.54A 3nu3B-1cziE:
6.7		 3nu3B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.53A 3nu4B-1cziE:
6.6		 3nu4B-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.87A 3nu5A-1cziE:
6.8		 3nu5A-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.73A 3nu5A-1cziE:
6.8		 3nu5A-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 3nu5B-1cziE:
6.7		 3nu5B-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.54A 3nu5B-1cziE:
6.7		 3nu5B-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 3nu6B-1cziE:
6.7		 3nu6B-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.61A 3nu6B-1cziE:
6.7		 3nu6B-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 3nujB-1cziE:
6.7		 3nujB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.57A 3nujB-1cziE:
6.7		 3nujB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.73A 3nuoB-1cziE:
6.6		 3nuoB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 3nuoB-1cziE:
6.6		 3nuoB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 3oxcB-1cziE:
6.5		 3oxcB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.59A 3oxvA-1cziE:
7.0		 3oxvA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 3oxvC-1cziE:
7.0		 3oxvC-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.60A 3oxvC-1cziE:
7.0		 3oxvC-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.69A 3oxxA-1cziE:
6.7		 3oxxA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ASP E  32
GLY E  34
GLY E  76
ASP E 215
THR E 218
ILE E 300
 None
 0.41A 3prsA-1cziE:
39.5		 3prsA-1cziE:
28.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 3pwmA-1cziE:
6.7		 3pwmA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.74A 3pwmB-1cziE:
6.7		 3pwmB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 3pwmB-1cziE:
6.7		 3pwmB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.55A 3pwrA-1cziE:
6.6		 3pwrA-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.42A 3pwrB-1cziE:
6.7		 3pwrB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ASP E  32
GLY E  76
LEU E  30
ILE E 213
THR E 218
ILE E 300
 None
 1.35A 3pwwA-1cziE:
39.5		 3pwwA-1cziE:
28.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ASP E  32
GLY E  76
PHE E 112
ILE E 213
THR E 218
ILE E 300
 None
 0.46A 3pwwA-1cziE:
39.5		 3pwwA-1cziE:
28.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 8 GLY E  34
SER E  35
ILE E  73
TYR E  75
ASP E 215
 None
 0.33A 3pwwA-1cziE:
39.5		 3pwwA-1cziE:
28.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1czi CHYMOSIN
(Bos
taurus) 		7 / 12 ILE E 120
ASP E  32
GLY E  34
GLY E  76
ASP E 215
THR E 218
ILE E 300
 None
 1.30A 3q70A-1cziE:
13.0		 3q70A-1cziE:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ILE E 213
ASP E 215
GLY E 217
GLY E  76
ASP E  32
 None
 0.59A 3q70A-1cziE:
13.0		 3q70A-1cziE:
31.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.52A 3s43B-1cziE:
6.5		 3s43B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.61A 3s45B-1cziE:
7.2		 3s45B-1cziE:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.52A 3s54A-1cziE:
6.7		 3s54A-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.54A 3s54B-1cziE:
6.6		 3s54B-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 138
ILE E  73
GLY E  34
ALA E 124
ALA E 129
 None
 1.02A 3sudB-1cziE:
undetectable		 3sudB-1cziE:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.48A 3tkgA-1cziE:
6.6		 3tkgA-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.52A 3tkgB-1cziE:
6.6		 3tkgB-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.53A 3tkgD-1cziE:
6.9		 3tkgD-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.65A 3tkwA-1cziE:
6.7		 3tkwA-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.76A 3tkwB-1cziE:
6.8		 3tkwB-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.63A 3tkwB-1cziE:
6.8		 3tkwB-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.52A 3tl9A-1cziE:
6.4		 3tl9A-1cziE:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.75A 3tl9B-1cziE:
6.8		 3tl9B-1cziE:
16.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ASP E  32
GLY E  34
ILE E  73
GLY E  76
ASP E 215
ILE E 300
 None
 0.41A 3tneA-1cziE:
36.7		 3tneA-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ILE E 120
ASP E  32
GLY E  34
GLY E  76
ASP E 215
ILE E 300
 None
 1.33A 3tneA-1cziE:
36.7		 3tneA-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ILE E 213
ASP E 215
GLY E 217
ASP E  32
ILE E 120
 None
 0.70A 3tneA-1cziE:
36.7		 3tneA-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ILE E 213
ASP E 215
GLY E 217
GLY E  76
ASP E  32
 None
 0.76A 3tneA-1cziE:
36.7		 3tneA-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ASP E  32
GLY E  34
ILE E  73
GLY E  76
ASP E 215
ILE E 300
 None
 0.43A 3tneB-1cziE:
36.7		 3tneB-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		6 / 12 ILE E 120
ASP E  32
GLY E  34
GLY E  76
ASP E 215
ILE E 300
 None
 1.30A 3tneB-1cziE:
36.7		 3tneB-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ILE E 213
ASP E 215
GLY E 217
ASP E  32
ILE E 120
 None
 0.71A 3tneB-1cziE:
36.7		 3tneB-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ILE E 213
ASP E 215
GLY E 217
GLY E  76
ASP E  32
 None
 0.73A 3tneB-1cziE:
36.7		 3tneB-1cziE:
33.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 7 SER E  35
TYR E  75
ILE E 120
THR E 218
 None
 0.42A 3tneB-1cziE:
36.7		 3tneB-1cziE:
33.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 6 GLU E 107
ASP E 110
ASP E 118
ASN E  52
 None
 1.24A 3vywA-1cziE:
undetectable		 3vywA-1cziE:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 5 GLU E 107
ASP E 110
ASP E 118
ASN E  52
 None
 1.24A 3vywD-1cziE:
undetectable		 3vywD-1cziE:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 6 SER E   3
GLU E 162
ASP E 156
ASP E 171
 None
 1.40A 4blvA-1cziE:
undetectable		 4blvA-1cziE:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.67A 4dqfB-1cziE:
6.8		 4dqfB-1cziE:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 4jecA-1cziE:
6.6		 4jecA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.62A 4jecA-1cziE:
6.6		 4jecA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.73A 4k8cA-1cziE:
undetectable		 4k8cA-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.72A 4kahA-1cziE:
undetectable		 4kahA-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.72A 4kahB-1cziE:
undetectable		 4kahB-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.72A 4kanA-1cziE:
undetectable		 4kanA-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.74A 4kanB-1cziE:
undetectable		 4kanB-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.76A 4kbeA-1cziE:
undetectable		 4kbeA-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.73A 4kbeB-1cziE:
undetectable		 4kbeB-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.73A 4lbgA-1cziE:
undetectable		 4lbgA-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1czi CHYMOSIN
(Bos
taurus) 		3 / 3 SER E  35
TYR E  75
PRO E 135
 None
 0.72A 4lbgB-1cziE:
undetectable		 4lbgB-1cziE:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.79A 4ll3B-1cziE:
6.8		 4ll3B-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.65A 4ll3B-1cziE:
6.8		 4ll3B-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.80A 4ll3A-1cziE:
6.8		 4ll3A-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 10 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.67A 4ll3A-1cziE:
6.8		 4ll3A-1cziE:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.73A 4njvB-1cziE:
6.7		 4njvB-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 11 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.72A 4njvC-1cziE:
6.6		 4njvC-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ALA E 115
PHE E 117
ILE E  73
GLY E  78
SER E 219
 None
 0.96A 4r20B-1cziE:
0.0		 4r20B-1cziE:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 4rvjB-1cziE:
6.6		 4rvjB-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 4rvjB-1cziE:
6.6		 4rvjB-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.76A 4rvjD-1cziE:
6.6		 4rvjD-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 9 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 4rvjD-1cziE:
6.6		 4rvjD-1cziE:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 VAL E 204
ILE E 231
TRP E 299
LEU E 301
LEU E 221
 None
 1.38A 4yvpB-1cziE:
undetectable		 4yvpB-1cziE:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 1czi CHYMOSIN
(Bos
taurus) 		4 / 7 VAL E 101
LEU E 103
SER E 104
GLU E 107
 None
 1.07A 4zphA-1cziE:
0.0
4zphB-1cziE:
0.0		 4zphA-1cziE:
21.52
4zphB-1cziE:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.59A 5e5jA-1cziE:
6.6		 5e5jA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.73A 5e5jB-1cziE:
6.7		 5e5jB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.58A 5e5kA-1cziE:
6.5		 5e5kA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 PHE E  27
LEU E 103
SER E  61
PHE E  64
ILE E  43
 None
 1.29A 5ljbA-1cziE:
undetectable		 5ljbA-1cziE:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 PHE E  27
LEU E 103
SER E  61
PHE E  64
ILE E  43
 None
 1.26A 5ljcA-1cziE:
undetectable		 5ljcA-1cziE:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.84A 5t2zB-1cziE:
6.7		 5t2zB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.69A 5t2zB-1cziE:
6.7		 5t2zB-1cziE:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.61A 5t8hA-1cziE:
6.6		 5t8hA-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.73A 5t8hB-1cziE:
6.8		 5t8hB-1cziE:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 6dgxA-1cziE:
6.4		 6dgxA-1cziE:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.77A 6dh3A-1cziE:
6.8		 6dh3A-1cziE:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.78A 6dh6A-1cziE:
6.4		 6dh6A-1cziE:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 LEU E  30
ASP E  32
GLY E  34
ASP E  37
ILE E 120
 None
 0.71A 6dh6A-1cziE:
6.4		 6dh6A-1cziE:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.63A 6difB-1cziE:
6.7		 6difB-1cziE:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 ASP E 215
GLY E 217
VAL E 222
GLY E  76
ILE E 300
 None
 0.60A 6dilB-1cziE:
6.7		 6dilB-1cziE:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 THR E 257
VAL E 259
VAL E 197
PHE E 305
VAL E 304
 None
 1.29A 6iblA-1cziE:
undetectable		 6iblA-1cziE:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 1czi CHYMOSIN
(Bos
taurus) 		5 / 12 THR E 257
VAL E 259
VAL E 197
PHE E 305
VAL E 304
 None
 1.29A 6iblB-1cziE:
undetectable		 6iblB-1cziE:
21.91