SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1czk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		6 / 7 THR A  11
THR A  56
TRP A  57
GLY A  89
ASP A  90
TYR A  94
 FMN  A 170 (-3.5A)
FMN  A 170 (-3.8A)
FMN  A 170 (-3.9A)
FMN  A 170 (-3.4A)
None
FMN  A 170 (-3.4A)
 0.77A 1bu5A-1czkA:
20.8		 1bu5A-1czkA:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 8 THR A  11
THR A  56
GLY A  89
ASP A  90
TYR A  94
 FMN  A 170 (-3.5A)
FMN  A 170 (-3.8A)
FMN  A 170 (-3.4A)
None
FMN  A 170 (-3.4A)
 0.47A 1bu5B-1czkA:
20.6		 1bu5B-1czkA:
32.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 8 THR A  56
TRP A  57
GLY A  89
ASP A  90
TYR A  94
 FMN  A 170 (-3.8A)
FMN  A 170 (-3.9A)
FMN  A 170 (-3.4A)
None
FMN  A 170 (-3.4A)
 0.62A 1bu5B-1czkA:
20.6		 1bu5B-1czkA:
32.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		3 / 3 VAL A 139
TRP A 120
TRP A 159
 None
 1.13A 1c4dA-1czkA:
undetectable
1c4dB-1czkA:
undetectable		 1c4dA-1czkA:
6.31
1c4dB-1czkA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 7 GLY A 124
GLN A 148
ARG A 155
ILE A 122
 None
 1.03A 1rxcD-1czkA:
2.9		 1rxcD-1czkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		3 / 3 THR A 152
ASP A  90
SER A  95
 None
 0.80A 2nxeA-1czkA:
undetectable		 2nxeA-1czkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		3 / 3 THR A 152
ASP A  90
SER A  95
 None
 0.80A 2nxeB-1czkA:
undetectable		 2nxeB-1czkA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 ILE A  17
ALA A  84
GLY A 140
GLY A  87
PHE A 167
 None
 1.15A 2okcB-1czkA:
undetectable		 2okcB-1czkA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 LEU A 141
PHE A  86
ILE A  17
ASP A 144
SER A 130
 None
 1.19A 3ko0A-1czkA:
undetectable
3ko0B-1czkA:
undetectable
3ko0C-1czkA:
undetectable
3ko0D-1czkA:
undetectable		 3ko0A-1czkA:
21.02
3ko0B-1czkA:
21.02
3ko0C-1czkA:
21.02
3ko0D-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 11 ASP A 144
LEU A 141
PHE A  86
ILE A  17
SER A 130
 None
 1.19A 3ko0C-1czkA:
undetectable
3ko0D-1czkA:
undetectable
3ko0E-1czkA:
undetectable
3ko0F-1czkA:
undetectable		 3ko0C-1czkA:
21.02
3ko0D-1czkA:
21.02
3ko0E-1czkA:
21.02
3ko0F-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 11 ASP A 144
LEU A 141
PHE A  86
ILE A  17
SER A 130
 None
 1.17A 3ko0E-1czkA:
undetectable
3ko0F-1czkA:
undetectable
3ko0G-1czkA:
undetectable
3ko0H-1czkA:
undetectable		 3ko0E-1czkA:
21.02
3ko0F-1czkA:
21.02
3ko0G-1czkA:
21.02
3ko0H-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 ASP A 144
LEU A 141
PHE A  86
ILE A  17
SER A 130
 None
 1.16A 3ko0G-1czkA:
undetectable
3ko0H-1czkA:
undetectable
3ko0I-1czkA:
undetectable
3ko0J-1czkA:
undetectable		 3ko0G-1czkA:
21.02
3ko0H-1czkA:
21.02
3ko0I-1czkA:
21.02
3ko0J-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 11 SER A 130
ASP A 144
LEU A 141
PHE A  86
ILE A  17
 None
 1.23A 3ko0A-1czkA:
undetectable
3ko0B-1czkA:
undetectable
3ko0I-1czkA:
undetectable
3ko0J-1czkA:
undetectable		 3ko0A-1czkA:
21.02
3ko0B-1czkA:
21.02
3ko0I-1czkA:
21.02
3ko0J-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 LEU A 141
PHE A  86
ILE A  17
ASP A 144
SER A 130
 None
 1.12A 3ko0K-1czkA:
undetectable
3ko0L-1czkA:
undetectable
3ko0S-1czkA:
undetectable
3ko0T-1czkA:
undetectable		 3ko0K-1czkA:
21.02
3ko0L-1czkA:
21.02
3ko0S-1czkA:
21.02
3ko0T-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 LEU A 141
PHE A  86
ILE A  17
ASP A 144
SER A 130
 None
 1.14A 3ko0M-1czkA:
undetectable
3ko0N-1czkA:
undetectable
3ko0O-1czkA:
undetectable
3ko0P-1czkA:
undetectable		 3ko0M-1czkA:
21.02
3ko0N-1czkA:
21.02
3ko0O-1czkA:
21.02
3ko0P-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 11 LEU A 141
PHE A  86
ILE A  17
ASP A 144
SER A 130
 None
 1.21A 3ko0O-1czkA:
undetectable
3ko0P-1czkA:
undetectable
3ko0Q-1czkA:
undetectable
3ko0R-1czkA:
undetectable		 3ko0O-1czkA:
21.02
3ko0P-1czkA:
21.02
3ko0Q-1czkA:
21.02
3ko0R-1czkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 6 GLY A 124
GLN A 148
ARG A 155
ILE A 122
 None
 1.08A 3kvvB-1czkA:
3.1		 3kvvB-1czkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 6 GLY A 124
GLN A 148
ARG A 155
ILE A 122
 None
 1.04A 3kvvC-1czkA:
3.0		 3kvvC-1czkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 6 GLY A 124
GLN A 148
ARG A 155
ILE A 122
 None
 1.12A 3kvvD-1czkA:
undetectable		 3kvvD-1czkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 6 GLY A 124
GLN A 148
ARG A 155
ILE A 122
 None
 1.07A 3kvvE-1czkA:
2.9		 3kvvE-1czkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		5 / 12 PHE A  78
ALA A 142
ALA A  88
THR A  14
ILE A  36
 None
None
FMN  A 170 (-3.8A)
FMN  A 170 (-3.5A)
None
 1.19A 6aybA-1czkA:
undetectable		 6aybA-1czkA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 1czk FLAVODOXIN
(Synechococcus
elongatus) 		4 / 7 ASN A  38
GLY A  53
VAL A  31
LEU A  33
 None
 0.71A 6dwnB-1czkA:
undetectable		 6dwnB-1czkA:
18.59