SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		3 / 3 GLU A 195
ASN A 194
TRP A  12
 None
 1.30A 1r15C-1d02A:
undetectable		 1r15C-1d02A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.94A 2eilN-1d02A:
undetectable
2eilW-1d02A:
undetectable		 2eilN-1d02A:
17.47
2eilW-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		5 / 12 ARG A 162
PHE A 152
GLY A 154
PRO A 182
VAL A 150
 None
 1.29A 2zznA-1d02A:
undetectable		 2zznA-1d02A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.94A 3abkA-1d02A:
undetectable
3abkJ-1d02A:
0.0		 3abkA-1d02A:
17.47
3abkJ-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.93A 3ablN-1d02A:
undetectable
3ablW-1d02A:
undetectable		 3ablN-1d02A:
17.47
3ablW-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.94A 3ag3N-1d02A:
undetectable
3ag3W-1d02A:
0.0		 3ag3N-1d02A:
17.47
3ag3W-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		3 / 3 ALA A 118
ARG A 121
LYS A 124
 None
 0.90A 3kp3B-1d02A:
undetectable		 3kp3B-1d02A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 7 HIS A  48
ILE A 137
TYR A 134
PRO A  82
 None
 1.14A 4g5jA-1d02A:
undetectable		 4g5jA-1d02A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 6 SER A 122
GLY A 104
ASP A 159
GLY A 116
 None
 0.94A 4koeA-1d02A:
undetectable
4koeB-1d02A:
0.0
4koeC-1d02A:
undetectable		 4koeA-1d02A:
17.62
4koeB-1d02A:
17.62
4koeC-1d02A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 7 SER A 122
GLY A 104
ASP A 159
GLY A 116
 None
 0.94A 4koeA-1d02A:
undetectable
4koeB-1d02A:
undetectable
4koeD-1d02A:
undetectable		 4koeA-1d02A:
17.62
4koeB-1d02A:
17.62
4koeD-1d02A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 5 TYR A  53
TYR A 134
GLU A  98
LEU A  49
 None
 1.14A 4qztB-1d02A:
0.0		 4qztB-1d02A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 6 GLY A 104
ASP A 159
GLY A 116
SER A 122
 None
 0.98A 4z53A-1d02A:
undetectable
4z53B-1d02A:
undetectable		 4z53A-1d02A:
14.07
4z53B-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		5 / 9 LEU A  49
HIS A  48
PRO A  46
GLY A 138
SER A  81
 None
 1.30A 5o96E-1d02A:
0.7
5o96F-1d02A:
0.0		 5o96E-1d02A:
20.45
5o96F-1d02A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.90A 5xdxN-1d02A:
undetectable
5xdxW-1d02A:
undetectable		 5xdxN-1d02A:
17.47
5xdxW-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.96A 5zcoA-1d02A:
undetectable
5zcoJ-1d02A:
undetectable		 5zcoA-1d02A:
17.47
5zcoJ-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.93A 5zcpN-1d02A:
undetectable
5zcpW-1d02A:
undetectable		 5zcpN-1d02A:
17.47
5zcpW-1d02A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1d02 TYPE II RESTRICTION
ENZYME MUNI
(Mycoplasma) 		4 / 8 ILE A  86
LEU A  42
PHE A  35
LEU A 189
 None
 0.94A 5zcqN-1d02A:
undetectable
5zcqW-1d02A:
undetectable		 5zcqN-1d02A:
17.47
5zcqW-1d02A:
14.07