SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)
1d06 NITROGEN FIXATION
REGULATORY PROTEIN
FIXL

(Sinorhizobium
meliloti)
4 / 8 MET A 202
LEU A 182
VAL A 232
GLY A 233
None
HEM  A 501 (-4.3A)
HEM  A 501 (-4.8A)
None
1.00A 1hrkA-1d06A:
undetectable
1hrkA-1d06A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)
1d06 NITROGEN FIXATION
REGULATORY PROTEIN
FIXL

(Sinorhizobium
meliloti)
4 / 8 MET A 202
LEU A 182
VAL A 232
GLY A 233
None
HEM  A 501 (-4.3A)
HEM  A 501 (-4.8A)
None
1.01A 1hrkB-1d06A:
undetectable
1hrkB-1d06A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)
1d06 NITROGEN FIXATION
REGULATORY PROTEIN
FIXL

(Sinorhizobium
meliloti)
5 / 12 VAL A 151
SER A 153
ASN A 181
ARG A 183
LEU A 198
HEM  A 501 (-4.3A)
HEM  A 501 ( 4.1A)
None
None
HEM  A 501 (-4.9A)
0.84A 4kuoA-1d06A:
11.2
4kuoA-1d06A:
29.86