SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 8 ILE A 179
LEU A 193
ARG A 184
THR A 186
LEU A 207
 None
 1.46A 2einA-1d0bA:
undetectable
2einJ-1d0bA:
0.0		 2einA-1d0bA:
17.05
2einJ-1d0bA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 6 ASN A  99
ASN A  76
ILE A  38
GLN A  72
 None
 1.24A 2hkkA-1d0bA:
undetectable		 2hkkA-1d0bA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		3 / 3 ILE A  81
ILE A  88
LEU A 144
 None
 0.55A 2prgA-1d0bA:
0.0		 2prgA-1d0bA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		6 / 12 LEU A 110
ASN A 108
GLY A 107
ILE A  82
VAL A  91
ILE A  88
 None
 1.39A 3bvbA-1d0bA:
undetectable		 3bvbA-1d0bA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		6 / 12 LEU A 110
ASN A 108
GLY A 107
ILE A  82
VAL A  91
ILE A  88
 None
 1.35A 3bvbB-1d0bA:
undetectable		 3bvbB-1d0bA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 7 LEU A 135
LEU A 204
VAL A 181
LEU A 169
 None
 0.70A 3g8iA-1d0bA:
undetectable		 3g8iA-1d0bA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 7 GLN A 240
SER A 216
LEU A 182
ILE A 220
 None
 0.98A 3ln1C-1d0bA:
undetectable		 3ln1C-1d0bA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		3 / 3 SER A 192
GLY A 172
SER A 216
 None
 0.60A 3loqA-1d0bA:
undetectable		 3loqA-1d0bA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 6 ILE A 179
LEU A 193
ARG A 184
THR A 186
 None
 1.19A 3wg7A-1d0bA:
undetectable
3wg7J-1d0bA:
0.0		 3wg7A-1d0bA:
17.05
3wg7J-1d0bA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 4 ASN A 108
VAL A  91
THR A  56
ILE A  57
 None
 1.42A 4retA-1d0bA:
0.0		 4retA-1d0bA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		4 / 4 ASN A 108
VAL A  91
THR A  56
ILE A  57
 None
 1.42A 4retC-1d0bA:
0.0		 4retC-1d0bA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 12 LEU A 110
ASN A 108
ILE A  82
VAL A  91
ILE A  88
 None
 1.07A 5kqyA-1d0bA:
undetectable		 5kqyA-1d0bA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 10 LEU A 110
ASN A 108
ILE A  82
VAL A  91
ILE A  88
 None
 1.00A 5kr1A-1d0bA:
undetectable		 5kr1A-1d0bA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 11 LEU A 110
ASN A 108
ILE A  82
VAL A  91
ILE A  88
 None
 1.05A 5kr2B-1d0bA:
undetectable		 5kr2B-1d0bA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 9 LEU A 110
ASN A 108
ILE A  82
VAL A  91
ILE A  88
 None
 1.05A 5kr2D-1d0bA:
undetectable		 5kr2D-1d0bA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 10 LEU A 125
GLY A 123
LEU A 116
LEU A 119
THR A 101
 None
 1.07A 5o96G-1d0bA:
undetectable
5o96H-1d0bA:
undetectable		 5o96G-1d0bA:
20.39
5o96H-1d0bA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 12 ILE A 220
VAL A 202
LEU A 237
LEU A 213
LEU A 235
 None
 1.28A 5tiwA-1d0bA:
undetectable		 5tiwA-1d0bA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1d0b INTERNALIN B
(Listeria
monocytogenes) 		5 / 12 LEU A  61
LEU A  97
PRO A  98
PHE A  48
THR A  42
 None
 1.25A 6debB-1d0bA:
undetectable		 6debB-1d0bA:
15.87