SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 8 PHE A 130
THR A 129
HIS A 119
HIS A  86
None
1.00A 1ei6C-1d0nA:
undetectable
1ei6C-1d0nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 670
ASP A 687
ASP A 665
None
0.71A 1eizA-1d0nA:
undetectable
1eizA-1d0nA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 670
ASP A 687
ASP A 665
None
0.76A 1ej0A-1d0nA:
undetectable
1ej0A-1d0nA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 ALA A 551
PHE A 539
VAL A 541
VAL A 568
None
0.56A 1epbA-1d0nA:
1.2
1epbA-1d0nA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 8 ALA A 551
PHE A 539
VAL A 541
VAL A 568
None
0.48A 1epbB-1d0nA:
0.0
1epbB-1d0nA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 GLU A 504
ALA A 506
SER A 544
None
0.71A 1errB-1d0nA:
0.0
1errB-1d0nA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 1v55A-1d0nA:
0.0
1v55C-1d0nA:
undetectable
1v55A-1d0nA:
20.91
1v55C-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 4 HIS A  86
ASP A 109
ASN A 113
ASP A  84
None
1.21A 1wg8A-1d0nA:
0.0
1wg8A-1d0nA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.26A 2dyrA-1d0nA:
0.0
2dyrC-1d0nA:
undetectable
2dyrA-1d0nA:
20.91
2dyrC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.19A 2dysA-1d0nA:
0.0
2dysC-1d0nA:
undetectable
2dysA-1d0nA:
20.91
2dysC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.22A 2eijA-1d0nA:
0.0
2eijC-1d0nA:
undetectable
2eijA-1d0nA:
20.91
2eijC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 2eilA-1d0nA:
undetectable
2eilC-1d0nA:
undetectable
2eilA-1d0nA:
20.91
2eilC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ARG A 120
SER A 336
TYR A  87
None
0.67A 2q2hA-1d0nA:
0.0
2q2hB-1d0nA:
0.0
2q2hA-1d0nA:
9.74
2q2hB-1d0nA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 ARG A 225
ASP A 192
ILE A 190
GLU A 224
None
1.47A 2xrzA-1d0nA:
undetectable
2xrzB-1d0nA:
undetectable
2xrzA-1d0nA:
20.56
2xrzB-1d0nA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.24A 2y69A-1d0nA:
0.0
2y69C-1d0nA:
undetectable
2y69A-1d0nA:
20.91
2y69C-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 LEU A  71
GLN A  82
THR A  73
THR A 105
None
1.06A 2zj0B-1d0nA:
undetectable
2zj0B-1d0nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 LEU A  71
GLN A  82
THR A  73
THR A 105
None
1.04A 2zj0C-1d0nA:
undetectable
2zj0C-1d0nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 4 LEU A  71
GLN A  82
THR A  73
THR A 105
None
1.07A 2zj0D-1d0nA:
undetectable
2zj0D-1d0nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 2zxwA-1d0nA:
0.0
2zxwC-1d0nA:
undetectable
2zxwA-1d0nA:
20.91
2zxwC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.24A 2zxwN-1d0nA:
0.0
2zxwP-1d0nA:
undetectable
2zxwN-1d0nA:
20.91
2zxwP-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 3abkA-1d0nA:
0.0
3abkC-1d0nA:
undetectable
3abkA-1d0nA:
20.91
3abkC-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 3ag2A-1d0nA:
0.0
3ag2C-1d0nA:
undetectable
3ag2A-1d0nA:
20.91
3ag2C-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.25A 3ag3A-1d0nA:
0.0
3ag3C-1d0nA:
undetectable
3ag3A-1d0nA:
20.91
3ag3C-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.24A 3ag3N-1d0nA:
0.0
3ag3P-1d0nA:
undetectable
3ag3N-1d0nA:
20.91
3ag3P-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 HIS A 309
ASP A 705
THR A 706
TYR A 703
None
1.23A 3ag4A-1d0nA:
0.0
3ag4C-1d0nA:
undetectable
3ag4A-1d0nA:
20.91
3ag4C-1d0nA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 LEU A  71
GLN A  82
THR A  73
THR A 105
None
1.07A 3ce6B-1d0nA:
undetectable
3ce6B-1d0nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 670
ASP A 687
ASP A 665
None
0.66A 3douA-1d0nA:
undetectable
3douA-1d0nA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 PRO A 726
VAL A 495
THR A 417
GLY A 416
None
1.16A 3elzB-1d0nA:
0.0
3elzB-1d0nA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 GLU A 327
VAL A 276
CYH A 304
None
0.99A 3fbxA-1d0nA:
2.5
3fbxA-1d0nA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 PHE A 305
GLY A 320
PHE A 294
PHE A 366
None
0.98A 3ko0D-1d0nA:
undetectable
3ko0E-1d0nA:
undetectable
3ko0D-1d0nA:
11.02
3ko0E-1d0nA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 PHE A 305
GLY A 320
PHE A 294
PHE A 366
None
0.90A 3ko0M-1d0nA:
0.7
3ko0P-1d0nA:
0.5
3ko0M-1d0nA:
11.02
3ko0P-1d0nA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 GLU A  28
LEU A  33
LEU A  71
None
0.71A 3ohtA-1d0nA:
undetectable
3ohtA-1d0nA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 GLU A  28
LEU A  33
LEU A  71
None
0.69A 3ohtB-1d0nA:
undetectable
3ohtB-1d0nA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 PHE A 130
THR A 129
ASP A  84
HIS A  86
None
1.11A 3t01A-1d0nA:
undetectable
3t01A-1d0nA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A  61
ARG A 161
LYS A 141
None
1.26A 3wipG-1d0nA:
undetectable
3wipG-1d0nA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASN A 206
GLU A 209
ARG A 210
None
0.91A 3wxoA-1d0nA:
0.0
3wxoA-1d0nA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 675
ARG A 641
ASP A 678
None
0.75A 4fp9A-1d0nA:
undetectable
4fp9A-1d0nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 675
ARG A 641
ASP A 678
None
0.73A 4fp9C-1d0nA:
undetectable
4fp9C-1d0nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
3 / 3 ASP A 675
ARG A 641
ASP A 678
None
0.75A 4fp9F-1d0nA:
undetectable
4fp9F-1d0nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 10 GLY A 731
VAL A 730
HIS A 455
LEU A 400
SER A 457
None
1.34A 4yb6C-1d0nA:
0.0
4yb6F-1d0nA:
0.0
4yb6C-1d0nA:
17.51
4yb6F-1d0nA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 10 HIS A 455
LEU A 400
SER A 457
GLY A 731
VAL A 730
None
1.32A 4yb6A-1d0nA:
0.0
4yb6D-1d0nA:
0.0
4yb6A-1d0nA:
17.51
4yb6D-1d0nA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 10 HIS A 455
LEU A 400
SER A 457
GLY A 731
VAL A 730
None
1.34A 4yb6D-1d0nA:
0.0
4yb6E-1d0nA:
0.0
4yb6D-1d0nA:
17.51
4yb6E-1d0nA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 PHE A 134
LEU A 138
TYR A 140
GLY A 132
SER A 127
None
1.36A 4zbrA-1d0nA:
undetectable
4zbrA-1d0nA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
6 / 12 GLY A 547
TYR A 464
ILE A 448
PHE A 441
THR A 549
MET A 517
None
1.34A 4zdyA-1d0nA:
0.0
4zdyA-1d0nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
6 / 12 GLY A 547
TYR A 464
ILE A 448
PHE A 441
THR A 549
MET A 517
None
1.28A 4ze2A-1d0nA:
0.1
4ze2A-1d0nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 7 ASP A 738
TRP A 736
THR A 404
SER A 457
None
1.34A 5b6iA-1d0nA:
undetectable
5b6iA-1d0nA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 ASP A 738
TRP A 736
THR A 404
SER A 457
None
1.36A 5b6iB-1d0nA:
0.0
5b6iB-1d0nA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 SER A 728
PRO A 727
PHE A 729
GLU A 725
None
1.23A 5b8iA-1d0nA:
undetectable
5b8iA-1d0nA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 GLY A 443
TYR A 520
GLY A 502
GLY A 439
PHE A 539
None
1.04A 5d4uA-1d0nA:
undetectable
5d4uA-1d0nA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 GLY A 443
TYR A 520
GLY A 502
GLY A 439
PHE A 539
None
1.01A 5d4uB-1d0nA:
undetectable
5d4uB-1d0nA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 4 LEU A 191
ARG A 225
ILE A 197
ILE A 220
None
0.75A 5dzk2-1d0nA:
undetectable
5dzkM-1d0nA:
0.0
5dzkN-1d0nA:
0.0
5dzk2-1d0nA:
1.46
5dzkM-1d0nA:
14.50
5dzkN-1d0nA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 LEU A 191
ARG A 225
ILE A 197
ILE A 220
None
0.79A 5dzk4-1d0nA:
undetectable
5dzkg-1d0nA:
0.0
5dzkm-1d0nA:
0.0
5dzkn-1d0nA:
0.0
5dzk4-1d0nA:
1.46
5dzkg-1d0nA:
15.07
5dzkm-1d0nA:
14.50
5dzkn-1d0nA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 6 PHE A 362
SER A 351
HIS A 119
LEU A 361
None
1.37A 5dzka-1d0nA:
undetectable
5dzko-1d0nA:
undetectable
5dzka-1d0nA:
15.07
5dzko-1d0nA:
1.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 4 ILE A 197
ILE A 220
ARG A 225
LEU A 191
None
0.90A 5dzkh-1d0nA:
0.0
5dzkn-1d0nA:
0.0
5dzkv-1d0nA:
undetectable
5dzkh-1d0nA:
14.50
5dzkn-1d0nA:
14.50
5dzkv-1d0nA:
1.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
4 / 5 ARG A 225
ILE A 197
ILE A 220
LEU A 191
None
0.87A 5dzki-1d0nA:
0.0
5dzkj-1d0nA:
0.0
5dzkx-1d0nA:
undetectable
5dzki-1d0nA:
14.50
5dzkj-1d0nA:
14.50
5dzkx-1d0nA:
1.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
6 / 12 GLY A 547
TYR A 464
ILE A 448
PHE A 441
THR A 549
MET A 517
None
1.35A 5eslA-1d0nA:
0.3
5eslA-1d0nA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 TYR A 464
ILE A 448
PHE A 441
THR A 549
MET A 517
None
1.26A 5jlcA-1d0nA:
0.1
5jlcA-1d0nA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 10 ILE A 654
VAL A 671
PHE A 652
SER A 699
GLU A 695
None
1.44A 5tixB-1d0nA:
undetectable
5tixB-1d0nA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 ASP A 192
ALA A 173
GLY A 219
ARG A 225
SER A 226
None
1.27A 6clxA-1d0nA:
undetectable
6clxA-1d0nA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 ASP A 192
GLY A 219
ARG A 225
SER A 226
ASP A  61
None
0.99A 6clxA-1d0nA:
undetectable
6clxA-1d0nA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1d0n HORSE PLASMA
GELSOLIN

(Equus
caballus)
5 / 12 GLY A 547
TYR A 464
PHE A 441
THR A 549
MET A 517
None
1.22A 6e8qA-1d0nA:
0.2
6e8qA-1d0nA:
8.06