SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1d0q DNA PRIMASE
(Geobacillus
stearothermophil
us) 		5 / 7 LEU A  29
GLY A  67
PRO A  41
VAL A  27
ILE A  23
 None
 1.29A 2aojB-1d0qA:
0.0		 2aojB-1d0qA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1d0q DNA PRIMASE
(Geobacillus
stearothermophil
us) 		3 / 3 CYH A  64
CYH A  40
HIS A  43
 ZN  A 151 (-2.4A)
ZN  A 151 (-2.3A)
ZN  A 151 (-3.1A)
 0.89A 3dtuB-1d0qA:
0.0		 3dtuB-1d0qA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 1d0q DNA PRIMASE
(Geobacillus
stearothermophil
us) 		3 / 3 CYH A  64
CYH A  40
HIS A  43
 ZN  A 151 (-2.4A)
ZN  A 151 (-2.3A)
ZN  A 151 (-3.1A)
 0.86A 3dtuD-1d0qA:
0.0		 3dtuD-1d0qA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1d0q DNA PRIMASE
(Geobacillus
stearothermophil
us) 		5 / 12 PRO A  48
SER A  51
ALA A  66
PRO A  41
PHE A  42
 None
 1.31A 5zvgA-1d0qA:
undetectable		 5zvgA-1d0qA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1d0q DNA PRIMASE
(Geobacillus
stearothermophil
us) 		5 / 12 PRO A  48
SER A  51
ALA A  66
PRO A  41
PHE A  42
 None
 1.33A 5zvgB-1d0qA:
undetectable		 5zvgB-1d0qA:
13.80