SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		5 / 6 VAL A  40
THR A  36
LEU A 137
ARG A 141
PHE A 140
 None
 1.43A 1s8fB-1d1dA:
undetectable		 1s8fB-1d1dA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		4 / 6 ALA A 186
ILE A 172
VAL A 175
GLU A 176
 None
 0.68A 2cizA-1d1dA:
0.0		 2cizA-1d1dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		5 / 12 LEU A 106
GLY A 108
GLN A 120
VAL A 114
LEU A  49
 None
 1.48A 3h52C-1d1dA:
undetectable		 3h52C-1d1dA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		5 / 11 MET A  44
LEU A  48
LEU A 129
GLU A 128
MET A  57
 None
 1.18A 3hm1B-1d1dA:
undetectable		 3hm1B-1d1dA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		5 / 12 ALA A 131
SER A 135
GLN A 120
GLY A 108
PRO A  50
 None
 1.11A 4uilH-1d1dA:
undetectable
4uilL-1d1dA:
undetectable		 4uilH-1d1dA:
19.12
4uilL-1d1dA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1d1d PROTEIN (CAPSID
PROTEIN)
(Rous
sarcoma
virus) 		5 / 8 ALA A  84
ALA A  83
ILE A  81
ALA A 134
LEU A  77
 None
 1.16A 4v1fA-1d1dA:
0.5
4v1fB-1d1dA:
0.7		 4v1fA-1d1dA:
18.75
4v1fB-1d1dA:
18.75