SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		3 / 3 PRO A 196
ASP A 200
ASP A 224
 None
 0.75A 1sqfA-1d1uA:
undetectable		 1sqfA-1d1uA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		5 / 11 ALA A  32
GLN A 221
LEU A 203
LEU A 226
LEU A 219
 None
 1.11A 2xn5A-1d1uA:
0.0		 2xn5A-1d1uA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		5 / 12 ASP A 225
ASP A 224
VAL A 223
ASN A 134
PRO A 132
 None
 1.08A 3dmfA-1d1uA:
undetectable		 3dmfA-1d1uA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		5 / 12 THR A  96
LEU A 198
SER A 195
SER A  56
ILE A 125
 None
 1.29A 3frqA-1d1uA:
undetectable		 3frqA-1d1uA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		4 / 7 LEU A 188
LEU A  48
PRO A  51
ILE A  50
 None
 0.94A 3s56B-1d1uA:
0.0		 3s56B-1d1uA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		3 / 3 PHE A 156
THR A  96
LEU A  87
 None
 0.78A 4qztA-1d1uA:
0.0		 4qztA-1d1uA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1d1u PROTEIN (REVERSE
TRANSCRIPTASE)
(Murine
leukemia
virus) 		4 / 8 LEU A 219
THR A 246
LEU A 247
LEU A 243
 None
 0.65A 4z90F-1d1uA:
0.0
4z90G-1d1uA:
0.0
4z90H-1d1uA:
0.0
4z90I-1d1uA:
0.0
4z90J-1d1uA:
0.0		 4z90F-1d1uA:
21.78
4z90G-1d1uA:
21.78
4z90H-1d1uA:
21.78
4z90I-1d1uA:
21.78
4z90J-1d1uA:
21.78