SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 1.02A 1v55P-1d2iA:
undetectable
1v55W-1d2iA:
0.0		 1v55P-1d2iA:
19.62
1v55W-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 1.03A 2dysP-1d2iA:
undetectable
2dysW-1d2iA:
undetectable		 2dysP-1d2iA:
19.62
2dysW-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.98A 2eijP-1d2iA:
undetectable
2eijW-1d2iA:
0.0		 2eijP-1d2iA:
19.62
2eijW-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.91A 2eimC-1d2iA:
undetectable
2eimJ-1d2iA:
0.0		 2eimC-1d2iA:
19.62
2eimJ-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.92A 2einC-1d2iA:
undetectable
2einJ-1d2iA:
0.0		 2einC-1d2iA:
19.62
2einJ-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 6 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.99A 2einP-1d2iA:
undetectable
2einW-1d2iA:
0.0		 2einP-1d2iA:
19.62
2einW-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_A_3TCA302_1
(DEOXYCYTIDINE KINASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 12 ILE A  72
GLU A  93
ALA A 127
ARG A 108
PHE A 112
 None
 1.33A 2noaA-1d2iA:
0.6		 2noaA-1d2iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 7 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.99A 2zxwC-1d2iA:
undetectable
2zxwJ-1d2iA:
0.0		 2zxwC-1d2iA:
19.62
2zxwJ-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 6 LEU A 102
GLN A  95
LEU A 152
PHE A 161
 None
MG  A 601 ( 4.1A)
None
None
 0.95A 2zxwP-1d2iA:
undetectable
2zxwW-1d2iA:
0.0		 2zxwP-1d2iA:
19.62
2zxwW-1d2iA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 12 HIS A  33
LEU A 170
VAL A 168
ILE A 128
LYS A   1
 None
 1.06A 3g9eA-1d2iA:
undetectable		 3g9eA-1d2iA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 4 GLY A 133
TYR A 145
GLY A 169
ASP A   4
 None
 0.93A 3kl3A-1d2iA:
undetectable		 3kl3A-1d2iA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 5 LEU A  91
ILE A  72
PRO A  73
PHE A  76
 None
 1.16A 3s3vA-1d2iA:
0.0		 3s3vA-1d2iA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 9 ILE A  70
GLY A 123
PRO A  73
ILE A  72
ILE A  83
 None
 0.91A 3s45A-1d2iA:
undetectable		 3s45A-1d2iA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 5 GLY A  52
VAL A  51
ASP A  49
THR A 183
 None
 1.26A 3vqrB-1d2iA:
undetectable		 3vqrB-1d2iA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 12 VAL A 126
VAL A  92
LEU A  15
ARG A 166
LEU A  27
 None
 0.95A 4i1rA-1d2iA:
0.9		 4i1rA-1d2iA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 4 LEU A  91
ILE A 128
GLY A  86
ILE A  23
 None
 0.73A 5dzk3-1d2iA:
undetectable
5dzkm-1d2iA:
undetectable		 5dzk3-1d2iA:
1.94
5dzkm-1d2iA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 5 ILE A 128
GLY A  86
ILE A  23
LEU A  91
 None
 0.72A 5dzkB-1d2iA:
0.9
5dzkI-1d2iA:
undetectable
5dzkW-1d2iA:
undetectable		 5dzkB-1d2iA:
22.83
5dzkI-1d2iA:
24.39
5dzkW-1d2iA:
1.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 5 ILE A 128
GLY A  86
ILE A  23
LEU A  91
 None
 0.76A 5dzki-1d2iA:
undetectable
5dzkj-1d2iA:
undetectable
5dzkx-1d2iA:
undetectable		 5dzki-1d2iA:
24.39
5dzkj-1d2iA:
24.39
5dzkx-1d2iA:
1.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 12 ILE A  70
GLY A 123
PRO A  73
ILE A  72
ILE A  83
 None
 0.87A 5e5jB-1d2iA:
undetectable		 5e5jB-1d2iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		4 / 8 MET A 117
LEU A  91
ILE A  83
LEU A 152
 None
 0.91A 5ieoA-1d2iA:
undetectable		 5ieoA-1d2iA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 1d2i PROTEIN (RESTRICTION
ENDONUCLEASE BGLII)
(Bacillus
subtilis) 		5 / 12 PHE A 174
LEU A 167
THR A 131
GLY A 133
MET A 135
 None
 1.22A 5ifuA-1d2iA:
undetectable		 5ifuA-1d2iA:
17.22