SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 6 ASP A 608
TYR A 609
ASP A 547
ASN A 550
 None
 1.15A 1rjdA-1d2oA:
undetectable		 1rjdA-1d2oA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 6 ASP A 608
TYR A 609
ASP A 547
ASN A 550
 None
 1.14A 1rjdB-1d2oA:
undetectable		 1rjdB-1d2oA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 6 ASP A 608
TYR A 609
ASP A 547
ASN A 550
 None
 1.15A 1rjdC-1d2oA:
undetectable		 1rjdC-1d2oA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 11 GLU A 535
VAL A 570
LEU A 588
THR A 536
THR A 537
 None
 1.31A 3iaiA-1d2oA:
undetectable		 3iaiA-1d2oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 11 GLU A 535
VAL A 570
LEU A 588
THR A 536
THR A 537
 None
 1.32A 3iaiB-1d2oA:
undetectable		 3iaiB-1d2oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 11 GLU A 535
VAL A 570
LEU A 588
THR A 536
THR A 537
 None
 1.30A 3iaiC-1d2oA:
undetectable		 3iaiC-1d2oA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 5 SER A 560
THR A 572
GLU A 603
ASP A 612
 None
 1.43A 3tm4A-1d2oA:
undetectable		 3tm4A-1d2oA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 5 SER A 560
THR A 572
GLU A 603
ASP A 612
 None
 1.41A 3tm4B-1d2oA:
undetectable		 3tm4B-1d2oA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		4 / 7 VAL A 559
ILE A 618
THR A 610
THR A 627
 None
 1.00A 3tneB-1d2oA:
undetectable		 3tneB-1d2oA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		5 / 9 PRO A 589
VAL A 570
LEU A 563
ASN A 566
ILE A 597
 None
 1.42A 4c66A-1d2oA:
undetectable		 4c66A-1d2oA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1d2o COLLAGEN ADHESIN
(Staphylococcus
aureus) 		3 / 3 ASP A 709
VAL A 705
ASN A 562
 None
 0.66A 4lmnA-1d2oA:
0.0		 4lmnA-1d2oA:
18.29