SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 SER A 293
GLU A 294
GLU A 295
 None
 0.69A 1eqbD-1d2rA:
1.6		 1eqbD-1d2rA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 SER A 293
GLU A 294
GLU A 295
 None
 0.69A 1eqbB-1d2rA:
1.6		 1eqbB-1d2rA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 7 PHE A  26
ALA A  22
ILE A   8
ILE A  14
 None
 0.86A 1oniD-1d2rA:
0.0
1oniF-1d2rA:
0.0		 1oniD-1d2rA:
18.21
1oniF-1d2rA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  93
PRO A 127
LEU A 157
ARG A 164
 None
 1.40A 2hrcA-1d2rA:
0.4		 2hrcA-1d2rA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  93
PRO A 127
LEU A 157
ARG A 164
 None
 1.22A 2hrcB-1d2rA:
undetectable		 2hrcB-1d2rA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 LEU A  61
TYR A  65
GLY A  69
 None
 0.64A 2ocuA-1d2rA:
undetectable		 2ocuA-1d2rA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  93
PRO A 127
LEU A 157
ARG A 164
 None
 1.47A 2qd2A-1d2rA:
undetectable		 2qd2A-1d2rA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 HIS A 150
MET A 129
MET A 105
 None
 0.94A 2vj1A-1d2rA:
undetectable		 2vj1A-1d2rA:
21.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		10 / 10 GLY A   7
GLN A   9
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.51A 3fhjA-1d2rA:
42.1		 3fhjA-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		10 / 10 GLY A   7
GLN A   9
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.55A 3fhjB-1d2rA:
40.6		 3fhjB-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		10 / 10 GLY A   7
GLN A   9
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.52A 3fhjC-1d2rA:
38.8		 3fhjC-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.49A 3fhjD-1d2rA:
40.7		 3fhjD-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		10 / 10 GLY A   7
GLN A   9
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.48A 3fhjE-1d2rA:
40.9		 3fhjE-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.49A 3fhjF-1d2rA:
42.4		 3fhjF-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.52A 3fi0A-1d2rA:
41.4		 3fi0A-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A   7
VAL A  40
HIS A  43
ASP A 132
VAL A 141
 None
 1.15A 3fi0A-1d2rA:
41.4		 3fi0A-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 8 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.44A 3fi0B-1d2rA:
40.9		 3fi0B-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.52A 3fi0C-1d2rA:
41.4		 3fi0C-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.67A 3fi0D-1d2rA:
42.0		 3fi0D-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.49A 3fi0D-1d2rA:
42.0		 3fi0D-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		7 / 7 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.42A 3fi0E-1d2rA:
39.9		 3fi0E-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A   7
VAL A  40
HIS A  43
VAL A 143
 None
 0.84A 3fi0E-1d2rA:
39.9		 3fi0E-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.65A 3fi0F-1d2rA:
41.1		 3fi0F-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 8 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.52A 3fi0G-1d2rA:
42.3		 3fi0G-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.47A 3fi0H-1d2rA:
41.9		 3fi0H-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 8 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.47A 3fi0I-1d2rA:
41.4		 3fi0I-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.68A 3fi0J-1d2rA:
41.9		 3fi0J-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.47A 3fi0K-1d2rA:
40.7		 3fi0K-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.61A 3fi0L-1d2rA:
41.8		 3fi0L-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.51A 3fi0M-1d2rA:
41.5		 3fi0M-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.51A 3fi0N-1d2rA:
41.9		 3fi0N-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.56A 3fi0O-1d2rA:
41.8		 3fi0O-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		7 / 7 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
GLN A 147
 None
 0.49A 3fi0P-1d2rA:
40.1		 3fi0P-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 8 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
 None
 0.40A 3fi0Q-1d2rA:
42.0		 3fi0Q-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.70A 3fi0R-1d2rA:
39.3		 3fi0R-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
VAL A 143
GLN A 147
 None
 0.53A 3fi0R-1d2rA:
39.3		 3fi0R-1d2rA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A   7
VAL A  40
HIS A  43
ASP A 132
VAL A 141
 None
 1.11A 3fi0R-1d2rA:
39.3		 3fi0R-1d2rA:
98.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A 133
ILE A 171
GLU A 159
LEU A 153
VAL A 141
 None
 1.22A 3fpjB-1d2rA:
2.3		 3fpjB-1d2rA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  93
PRO A 127
LEU A 157
ARG A 164
 None
 1.32A 3hcoB-1d2rA:
2.0		 3hcoB-1d2rA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 272
ALA A 220
MET A 193
ILE A 213
ILE A  16
 None
 1.13A 3ut5B-1d2rA:
undetectable		 3ut5B-1d2rA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 201
PRO A 200
LYS A 215
 None
 1.15A 4dr5L-1d2rA:
0.0		 4dr5L-1d2rA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 201
PRO A 200
LYS A 215
 None
 1.12A 4dr6L-1d2rA:
0.0		 4dr6L-1d2rA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 ALA A 130
LEU A 128
PHE A   5
SER A   6
THR A 154
 None
 1.21A 4eckA-1d2rA:
undetectable		 4eckA-1d2rA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 272
ALA A 220
MET A 193
ILE A 213
ILE A  16
 None
 1.07A 4o2bB-1d2rA:
undetectable		 4o2bB-1d2rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A 183
ILE A 253
LEU A 248
LEU A 241
ILE A 213
 None
 1.00A 4pd4C-1d2rA:
undetectable		 4pd4C-1d2rA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 272
ALA A 220
MET A 193
ILE A 213
ILE A  16
 None
 1.11A 5itzB-1d2rA:
undetectable		 5itzB-1d2rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 272
ALA A 220
MET A 193
ILE A 213
ILE A  16
 None
 1.03A 5mioB-1d2rA:
undetectable		 5mioB-1d2rA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		9 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.50A 5v0iA-1d2rA:
42.5		 5v0iA-1d2rA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A   7
VAL A  40
HIS A  43
MET A 129
VAL A 143
 None
 1.27A 5v0iA-1d2rA:
42.5		 5v0iA-1d2rA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
GLN A   9
VAL A  40
HIS A  43
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.48A 5v0iB-1d2rA:
42.2		 5v0iB-1d2rA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		8 / 9 GLY A   7
VAL A  40
HIS A  43
MET A 129
ASP A 132
ILE A 133
VAL A 141
GLN A 147
 None
 0.50A 5v0iB-1d2rA:
42.2		 5v0iB-1d2rA:
57.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A   7
VAL A  40
HIS A  43
MET A 129
VAL A 143
 None
 1.34A 5v0iB-1d2rA:
42.2		 5v0iB-1d2rA:
57.23