SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG B  49
ARG B  65
ARG A  69
 GOL  B 611 (-4.2A)
None
GOL  B 608 (-4.0A)
 1.21A 2jb7A-1d3bB:
0.7
2jb7B-1d3bB:
0.7
2jb7C-1d3bB:
0.0		 2jb7A-1d3bB:
18.90
2jb7B-1d3bB:
18.90
2jb7C-1d3bB:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG B  65
ARG A  69
ARG B  49
 None
GOL  B 608 (-4.0A)
GOL  B 611 (-4.2A)
 1.20A 2jb7A-1d3bB:
0.7
2jb7B-1d3bB:
0.7
2jb7C-1d3bB:
0.0		 2jb7A-1d3bB:
18.90
2jb7B-1d3bB:
18.90
2jb7C-1d3bB:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens) 		5 / 12 LEU B  21
ASN B  76
LEU B  77
GLY B  74
VAL B  70
 GOL  B 608 ( 4.5A)
GOL  B 608 (-3.3A)
CIT  B 702 (-4.4A)
None
None
 1.31A 2q7lA-1d3bB:
undetectable		 2q7lA-1d3bB:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		3 / 3 PRO A   6
ASN B  39
ARG B  73
 None
 0.93A 2qeuB-1d3bA:
undetectable		 2qeuB-1d3bA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		5 / 12 GLY A  65
LEU B  77
GLY B  74
LEU B  72
LEU B  42
 None
CIT  B 702 (-4.4A)
None
None
None
 1.10A 2zbpA-1d3bA:
undetectable		 2zbpA-1d3bA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		4 / 4 LEU A  73
PRO A  74
LEU B  69
ILE B  41
 None
GOL  A 614 (-3.5A)
None
None
 0.96A 4f4dB-1d3bA:
undetectable		 4f4dB-1d3bA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		4 / 5 LEU A  73
PRO A  74
LEU B  69
ILE B  41
 None
GOL  A 614 (-3.5A)
None
None
 0.76A 4klrA-1d3bA:
undetectable		 4klrA-1d3bA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN
ASSOCIATED PROTEIN
B)
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP B  23
ASN A  23
SER B  79
 GOL  B 608 ( 2.9A)
GOL  B 608 (-3.4A)
None
 0.75A 4obwA-1d3bB:
undetectable		 4obwA-1d3bB:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1d3b PROTEIN (SMALL
NUCLEAR
RIBONUCLEOPROTEIN SM
D3)
(Homo
sapiens) 		5 / 12 LEU A  58
THR A  24
ILE A  17
ARG A  54
TYR A  50
 None
None
GOL  A 614 (-4.6A)
None
None
 1.44A 5dlvA-1d3bA:
undetectable		 5dlvA-1d3bA:
7.06