SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		5 / 11 LEU A 150
VAL A 141
ILE A 156
ALA A 170
LEU A   9
 None
 1.18A 2q72A-1d3uA:
undetectable		 2q72A-1d3uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		4 / 5 LEU A 117
GLY A 136
ILE A 156
VAL A 157
 None
 0.89A 3wriA-1d3uA:
0.0		 3wriA-1d3uA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		4 / 5 LEU A 117
GLY A 136
ILE A 156
VAL A 157
 None
 0.90A 3wriB-1d3uA:
0.0		 3wriB-1d3uA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		4 / 7 GLY A 160
ALA A 170
SER A 146
GLU A 169
 None
 0.84A 4hyfA-1d3uA:
undetectable		 4hyfA-1d3uA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		4 / 8 GLY A 160
ALA A 170
SER A 146
GLU A 169
 None
 0.89A 4hyfB-1d3uA:
undetectable		 4hyfB-1d3uA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		4 / 8 GLY A 160
ALA A 170
SER A 146
GLU A 169
 None
 0.83A 4hyfC-1d3uA:
undetectable		 4hyfC-1d3uA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 1d3u TATA-BINDING PROTEIN
(Pyrococcus
woesei) 		3 / 3 VAL A 157
GLY A 109
LYS A 155
 None
 0.77A 4k50E-1d3uA:
0.0		 4k50E-1d3uA:
22.34