SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_B_SAMB298_0 (PUTATIVE MODIFICATION METHYLASE)	1d4m	PROTEIN (COXSACKIEVIRUS A9) (Enterovirus B)	5 / 12	ALA 1 177 PRO 1 178 GLY 1 175 LEU 1 140 VAL 1 139	None	1.21A	2zifB-1d4m1: undetectable	2zifB-1d4m1: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LRH_D_FOLD301_1 (FOLATE RECEPTOR ALPHA)	1d4m	PROTEIN (COXSACKIEVIRUS A9) (Enterovirus B)	3 / 3	HIS 1 223 TRP 1 162 SER 1 125	None	1.11A	4lrhD-1d4m1: undetectable	4lrhD-1d4m1: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	1d4m	PROTEIN (COXSACKIEVIRUS A9) (Enterovirus B)	3 / 3	ASP 1 159 TYR 1 160 TRP 1 162	None	1.20A	4p7nA-1d4m1: undetectable	4p7nA-1d4m1: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_D_CVID301_0 (REGULATORY PROTEIN TETR)	1d4m	PROTEIN (COXSACKIEVIRUS A9) (Enterovirus B)	5 / 12	MET 1 103 ALA 1 72 TYR 1 192 VAL 1 119 PHE 1 121	None None W71 1 501 ( 3.7A) None None	1.38A	5vlmD-1d4m1: undetectable	5vlmD-1d4m1: 18.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZIF_B_SAMB298_0","PUTATIVE MODIFICATION METHYLASE","1d4m","PROTEIN (COXSACKIEVIRUS A9)","Enterovirus B",5,"ALA 1 177;PRO 1 178;GLY 1 175;LEU 1 140;VAL 1 139","None","1.21A","2zifB-1d4m1:undetectable","2zifB-1d4m1:20.48"],["4LRH_D_FOLD301_1","FOLATE RECEPTOR ALPHA","1d4m","PROTEIN (COXSACKIEVIRUS A9)","Enterovirus B",3,"HIS 1 223;TRP 1 162;SER 1 125","None","1.11A","4lrhD-1d4m1:undetectable","4lrhD-1d4m1:18.93"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","1d4m","PROTEIN (COXSACKIEVIRUS A9)","Enterovirus B",3,"ASP 1 159;TYR 1 160;TRP 1 162","None","1.20A","4p7nA-1d4m1:undetectable","4p7nA-1d4m1:18.18"],["5VLM_D_CVID301_0","REGULATORY PROTEIN TETR","1d4m","PROTEIN (COXSACKIEVIRUS A9)","Enterovirus B",5,"MET 1 103;ALA 1  72;TYR 1 192;VAL 1 119;PHE 1 121","None;None;W71 1 501 ( 3.7A);None;None","1.38A","5vlmD-1d4m1:undetectable","5vlmD-1d4m1:18.24"]]