SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 HIS A 303
SER A 191
LEU A 105
GLY A 216
 None
 0.98A 1a4lB-1d6hA:
undetectable		 1a4lB-1d6hA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 9 VAL A 135
GLY A 134
THR A 131
VAL A 129
ASP A 141
 None
 1.39A 1dz8A-1d6hA:
undetectable		 1dz8A-1d6hA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 9 VAL A 135
GLY A 134
THR A 131
VAL A 129
ASP A 141
 None
 1.39A 1dz8B-1d6hA:
undetectable		 1dz8B-1d6hA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 VAL A 382
LEU A 370
VAL A 224
ILE A  19
ILE A  22
 None
 1.00A 1epbA-1d6hA:
undetectable		 1epbA-1d6hA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 VAL A 382
LEU A 370
VAL A 224
ILE A  19
ILE A  22
 None
 0.89A 1epbB-1d6hA:
0.0		 1epbB-1d6hA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 PHE A 373
LEU A 310
VAL A 313
VAL A 369
 None
 1.19A 1t88B-1d6hA:
undetectable		 1t88B-1d6hA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 11 SER A 191
ALA A 140
LEU A 144
VAL A  98
VAL A  99
 None
 1.14A 1ukbA-1d6hA:
undetectable		 1ukbA-1d6hA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 TYR A  36
VAL A  83
SER A 208
GLY A 216
ILE A  65
 None
 1.36A 1xvaA-1d6hA:
undetectable		 1xvaA-1d6hA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 PHE A 373
LEU A 310
VAL A 313
VAL A 369
 None
 1.20A 2m56A-1d6hA:
0.0		 2m56A-1d6hA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 ILE A 309
HIS A 303
PHE A 215
GLY A 216
LEU A 343
 None
 0.94A 2nyrB-1d6hA:
undetectable		 2nyrB-1d6hA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 6 SER A 332
LYS A  66
GLU A  32
CYH A  30
 None
 1.42A 2x7hA-1d6hA:
undetectable		 2x7hA-1d6hA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 6 THR A 169
VAL A 170
GLU A 192
CYH A 190
 None
 1.14A 3b6rB-1d6hA:
undetectable		 3b6rB-1d6hA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		6 / 9 LEU A 283
VAL A 275
ILE A 309
ILE A 301
ALA A 282
ILE A 279
 None
 1.38A 3el0B-1d6hA:
undetectable		 3el0B-1d6hA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 VAL A 342
VAL A 369
PHE A 371
HIS A 303
 None
 1.07A 3fhxB-1d6hA:
undetectable		 3fhxB-1d6hA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		3 / 3 GLY A 305
ILE A 274
VAL A 275
 COA  A 390 (-4.6A)
None
None
 0.52A 3nv6A-1d6hA:
0.0		 3nv6A-1d6hA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 SER A 386
THR A 360
GLU A 238
ASP A 227
 None
 1.07A 3tm4A-1d6hA:
2.5		 3tm4A-1d6hA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 SER A 386
THR A 360
GLU A 238
ASP A 227
 None
 1.08A 3tm4B-1d6hA:
undetectable		 3tm4B-1d6hA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 VAL A 189
LEU A 187
ILE A 128
ASP A 141
 None
 0.72A 3wzeA-1d6hA:
undetectable		 3wzeA-1d6hA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 LEU A 384
ALA A 326
ILE A  19
CYH A 341
GLY A 167
 None
 1.10A 4hfpB-1d6hA:
undetectable		 4hfpB-1d6hA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 7 ILE A 114
LEU A 150
GLY A 149
TYR A 153
 None
 0.88A 4iqqA-1d6hA:
undetectable		 4iqqA-1d6hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 114
LEU A 150
GLY A 149
TYR A 153
 None
 0.86A 4iqqD-1d6hA:
0.0		 4iqqD-1d6hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 GLU A 238
ARG A 385
PRO A  16
SER A 226
 None
 1.40A 4k17B-1d6hA:
undetectable		 4k17B-1d6hA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 6 PHE A 373
LEU A 310
VAL A 313
VAL A 369
 None
 1.14A 4kkyX-1d6hA:
undetectable		 4kkyX-1d6hA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 5 PHE A 373
LEU A 310
VAL A 313
VAL A 369
 None
 1.21A 4l49A-1d6hA:
0.0		 4l49A-1d6hA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 SER A 339
GLY A 168
GLY A 167
PHE A 165
GLN A 162
 None
 1.10A 4ubeA-1d6hA:
undetectable		 4ubeA-1d6hA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 7 PHE A 287
LEU A 290
SER A 297
VAL A 383
 None
 0.91A 4wnvD-1d6hA:
0.0		 4wnvD-1d6hA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 236
ALA A  17
THR A  18
VAL A 224
 None
 0.89A 5ecnD-1d6hA:
0.0		 5ecnD-1d6hA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		3 / 3 ARG A   8
ASN A 181
ASP A 227
 None
 0.82A 5gwxA-1d6hA:
undetectable		 5gwxA-1d6hA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 7 ILE A 114
LEU A 150
GLY A 149
TYR A 153
 None
 0.80A 5h3aB-1d6hA:
0.0		 5h3aB-1d6hA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 GLU A 238
PRO A 228
GLY A  15
PRO A  16
 None
 1.00A 5kf8A-1d6hA:
0.0		 5kf8A-1d6hA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 7 PHE A 265
GLY A 163
GLY A 374
HIS A 303
 None
 1.04A 5n9xA-1d6hA:
undetectable		 5n9xA-1d6hA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 114
LEU A 150
GLY A 149
TYR A 153
 None
 0.90A 5nooD-1d6hA:
0.0		 5nooD-1d6hA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		3 / 3 LEU A 283
ALA A 282
LEU A 317
 None
 0.54A 5uunB-1d6hA:
0.0		 5uunB-1d6hA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 6 ILE A 114
LEU A 150
GLY A 149
TYR A 153
 None
 0.87A 5x5qE-1d6hA:
undetectable		 5x5qE-1d6hA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 7 PHE A 373
GLY A 374
GLY A 376
THR A 132
 None
 0.74A 5ybbB-1d6hA:
undetectable		 5ybbB-1d6hA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 12 LEU A 377
ILE A 379
GLY A 372
VAL A 313
ILE A 309
 None
 0.98A 5ycnA-1d6hA:
undetectable		 5ycnA-1d6hA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		5 / 9 VAL A 129
GLY A 218
VAL A 193
GLU A 192
PRO A  27
 None
 1.31A 5zniA-1d6hA:
undetectable		 5zniA-1d6hA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		3 / 3 PHE A  39
ASP A  38
LYS A  42
 None
 0.83A 6awtD-1d6hA:
0.0		 6awtD-1d6hA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		3 / 3 GLU A 179
ASP A 227
PRO A 228
 None
 0.33A 6berA-1d6hA:
undetectable		 6berA-1d6hA:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 246
THR A 245
GLN A 244
THR A 169
 None
 1.02A 6c06C-1d6hA:
0.0		 6c06C-1d6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 246
THR A 245
THR A 169
ARG A 172
 None
 0.83A 6c06C-1d6hA:
0.0		 6c06C-1d6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 TYR A 160
VAL A 102
ASP A 141
VAL A 189
 None
 1.08A 6cp4A-1d6hA:
undetectable		 6cp4A-1d6hA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1d6h CHALCONE SYNTHASE
(Medicago
sativa) 		4 / 8 ILE A 246
GLN A 244
THR A 169
VAL A 170
 None
 0.90A 6fbvC-1d6hA:
0.0		 6fbvC-1d6hA:
17.15