SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ALA A 238
VAL A 224
TRP A 240
 None
 0.95A 1av2A-1d6mA:
undetectable
1av2B-1d6mA:
undetectable		 1av2A-1d6mA:
3.41
1av2B-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 TRP A 240
ALA A 238
VAL A 224
 None
 0.76A 1av2C-1d6mA:
undetectable
1av2D-1d6mA:
undetectable		 1av2C-1d6mA:
3.41
1av2D-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 496
PHE A 491
LEU A 541
ILE A 503
LEU A 557
 None
 1.20A 1hrkA-1d6mA:
3.4		 1hrkA-1d6mA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A  85
VAL A  81
SER A  80
VAL A 115
LEU A 111
 None
 1.34A 1ie9A-1d6mA:
0.0		 1ie9A-1d6mA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 11 ALA A 309
ALA A 302
LEU A 405
GLN A 409
ARG A 334
 None
 1.36A 1iiuA-1d6mA:
0.5		 1iiuA-1d6mA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 ALA A 407
ILE A 406
ILE A 351
VAL A 347
ALA A 388
 None
 1.01A 1uduB-1d6mA:
undetectable		 1uduB-1d6mA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 TRP A 240
ALA A 238
VAL A 224
 None
 0.90A 1w5uA-1d6mA:
undetectable
1w5uB-1d6mA:
undetectable		 1w5uA-1d6mA:
3.41
1w5uB-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 LEU A 205
PHE A 506
ARG A 489
 None
 0.82A 1xdkB-1d6mA:
0.0		 1xdkB-1d6mA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 LEU A 205
PHE A 506
ARG A 489
 None
 0.82A 1xdkF-1d6mA:
undetectable		 1xdkF-1d6mA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.18A 2htuA-1d6mA:
undetectable		 2htuA-1d6mA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ALA A 238
VAL A 224
TRP A 240
 None
 0.77A 2izqA-1d6mA:
undetectable
2izqB-1d6mA:
undetectable		 2izqA-1d6mA:
3.41
2izqB-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASN A 152
ARG A 131
ASP A 379
 None
 0.92A 2qe6A-1d6mA:
undetectable		 2qe6A-1d6mA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASN A 175
ARG A 178
ASP A  55
 None
 0.98A 2qe6A-1d6mA:
undetectable		 2qe6A-1d6mA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASN A 152
ARG A 131
ASP A 379
 None
 0.96A 2qe6B-1d6mA:
undetectable		 2qe6B-1d6mA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASN A 175
ARG A 178
ASP A  55
 None
 0.97A 2qe6B-1d6mA:
undetectable		 2qe6B-1d6mA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 GLU A 458
GLU A 457
TRP A 446
 None
 0.90A 3hrdA-1d6mA:
0.0
3hrdE-1d6mA:
0.0
3hrdF-1d6mA:
0.0		 3hrdA-1d6mA:
20.54
3hrdE-1d6mA:
20.54
3hrdF-1d6mA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.31A 3k37A-1d6mA:
undetectable		 3k37A-1d6mA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.29A 3k39A-1d6mA:
undetectable		 3k39A-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.30A 3k39E-1d6mA:
undetectable		 3k39E-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.30A 3k39F-1d6mA:
undetectable		 3k39F-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.28A 3k39G-1d6mA:
undetectable		 3k39G-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.31A 3k39H-1d6mA:
undetectable		 3k39H-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.29A 3k39M-1d6mA:
undetectable		 3k39M-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.30A 3k39N-1d6mA:
undetectable		 3k39N-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.28A 3k39O-1d6mA:
undetectable		 3k39O-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 LEU A 133
ARG A 131
ARG A 106
GLU A 525
TYR A 328
 None
 1.29A 3k39P-1d6mA:
undetectable		 3k39P-1d6mA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 TRP A 240
ALA A 238
VAL A 224
 None
 0.75A 3l8lA-1d6mA:
undetectable
3l8lB-1d6mA:
undetectable		 3l8lA-1d6mA:
3.41
3l8lB-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 TRP A 240
ALA A 238
VAL A 224
 None
 0.94A 3l8lC-1d6mA:
undetectable
3l8lD-1d6mA:
undetectable		 3l8lC-1d6mA:
3.41
3l8lD-1d6mA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		6 / 12 TYR A 180
LEU A 561
LEU A 599
LEU A 602
ALA A 168
TYR A 172
 None
 1.47A 3vw7A-1d6mA:
0.0		 3vw7A-1d6mA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 8 TYR A 172
THR A 566
ARG A 208
LEU A 205
 None
 1.20A 3wipG-1d6mA:
undetectable
3wipH-1d6mA:
undetectable		 3wipG-1d6mA:
16.04
3wipH-1d6mA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 8 ARG A 208
LEU A 205
TYR A 172
THR A 566
 None
 1.19A 3wipF-1d6mA:
undetectable
3wipJ-1d6mA:
undetectable		 3wipF-1d6mA:
16.04
3wipJ-1d6mA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 9 GLY A 102
ASN A 135
GLY A 108
TYR A 328
ASP A 105
 None
 1.29A 3ztvA-1d6mA:
undetectable		 3ztvA-1d6mA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 6 PHE A 236
ALA A 436
ALA A 226
LEU A 427
 None
 1.01A 4dtzA-1d6mA:
0.0		 4dtzA-1d6mA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 6 PHE A 236
ALA A 436
ALA A 226
LEU A 427
 None
 1.00A 4dtzB-1d6mA:
0.0		 4dtzB-1d6mA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASP A 569
ARG A 567
ASP A 511
 None
 0.82A 4fp9C-1d6mA:
undetectable		 4fp9C-1d6mA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ASP A 569
ARG A 567
ASP A 511
 None
 0.83A 4fp9F-1d6mA:
undetectable		 4fp9F-1d6mA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 ILE A 351
GLN A 409
LEU A 411
VAL A 364
ILE A 368
 None
 1.12A 4g1bD-1d6mA:
3.3		 4g1bD-1d6mA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 4 LYS A   8
LEU A  11
GLU A 321
LEU A 137
 None
 1.37A 4k4yE-1d6mA:
0.0		 4k4yE-1d6mA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 10 ILE A 503
ALA A 499
ILE A 532
LEU A 205
VAL A 202
 None
 1.03A 4rz7A-1d6mA:
0.0		 4rz7A-1d6mA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ARG A 208
GLN A 508
GLU A 563
 None
 0.81A 4tvtA-1d6mA:
0.0		 4tvtA-1d6mA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 7 THR A 598
LEU A 599
LEU A 595
THR A 571
 None
 0.89A 4z90A-1d6mA:
0.0
4z90B-1d6mA:
0.0
4z90C-1d6mA:
0.0
4z90D-1d6mA:
0.0
4z90E-1d6mA:
0.0		 4z90A-1d6mA:
20.74
4z90B-1d6mA:
20.74
4z90C-1d6mA:
20.74
4z90D-1d6mA:
20.74
4z90E-1d6mA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 ASP A 520
SER A 576
SER A 582
GLU A 583
GLU A 525
 None
 1.33A 5iqdC-1d6mA:
1.5		 5iqdC-1d6mA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 CYH A 475
LYS A 477
HIS A 227
 None
 1.28A 5js5A-1d6mA:
0.0		 5js5A-1d6mA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		5 / 12 ALA A 301
LEU A 307
PHE A 305
TYR A 403
ILE A 406
 None
 1.29A 5ljcA-1d6mA:
undetectable		 5ljcA-1d6mA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 HIS A 549
SER A 550
LYS A 555
 None
 1.27A 5os7A-1d6mA:
0.0		 5os7A-1d6mA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		4 / 5 LEU A 137
TYR A 328
LEU A  11
GLU A   7
 None
 1.34A 5weaA-1d6mA:
3.2		 5weaA-1d6mA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 HIS A 549
SER A 550
LYS A 555
 None
 1.27A 6gmdB-1d6mA:
0.0		 6gmdB-1d6mA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ARG A 167
LYS A  72
TYR A  54
 None
 1.11A 6gnaA-1d6mA:
0.0		 6gnaA-1d6mA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1d6m DNA TOPOISOMERASE
III
(Escherichia
coli) 		3 / 3 ARG A 167
LYS A  72
TYR A  54
 None
 1.11A 6gnbA-1d6mA:
0.0		 6gnbA-1d6mA:
18.66