SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1d6t RIBONUCLEASE P
(Staphylococcus
aureus) 		4 / 8 ILE A  66
ALA A  86
LEU A  53
ILE A  98
 None
 0.78A 2w9sE-1d6tA:
undetectable		 2w9sE-1d6tA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1d6t RIBONUCLEASE P
(Staphylococcus
aureus) 		5 / 12 ILE A  66
ASN A  69
HIS A 104
VAL A  84
PHE A 112
 None
 1.19A 4a97A-1d6tA:
0.0
4a97B-1d6tA:
0.0		 4a97A-1d6tA:
16.94
4a97B-1d6tA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1d6t RIBONUCLEASE P
(Staphylococcus
aureus) 		4 / 4 VAL A  25
ILE A  18
ASN A  37
VAL A 111
 None
 1.32A 5ajqA-1d6tA:
undetectable		 5ajqA-1d6tA:
16.27