SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1d7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 8 THR A  22
GLY A 122
GLY A  71
SER A 103
GLY A  69
 None
None
AIR  A 300 (-3.6A)
None
None
 1.34A 1jhqA-1d7aA:
5.2		 1jhqA-1d7aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 8 THR A  22
GLY A 122
GLY A  71
SER A 103
GLY A  69
 None
None
AIR  A 300 (-3.6A)
None
None
 1.37A 1jhvA-1d7aA:
5.3		 1jhvA-1d7aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 9 THR A  22
GLY A 122
GLY A  71
SER A 103
GLY A  69
 None
None
AIR  A 300 (-3.6A)
None
None
 1.36A 1jhyA-1d7aA:
5.2		 1jhyA-1d7aA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		4 / 6 TYR A  63
HIS A  38
PRO A  77
VAL A  42
 None
 1.11A 1q13A-1d7aA:
undetectable		 1q13A-1d7aA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		4 / 4 THR A  22
GLY A 100
ASP A 102
ALA A  96
 None
 0.79A 1sg9A-1d7aA:
4.2		 1sg9A-1d7aA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 11 GLY A  15
SER A  43
ILE A  80
HIS A  38
ALA A  68
 AIR  A 300 (-3.5A)
AIR  A 300 (-3.1A)
None
None
None
 1.35A 2a58A-1d7aA:
8.1
2a58E-1d7aA:
8.2		 2a58A-1d7aA:
23.50
2a58E-1d7aA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 11 ILE A  80
HIS A  38
ALA A  68
GLY A  15
SER A  43
 None
None
None
AIR  A 300 (-3.5A)
AIR  A 300 (-3.1A)
 1.35A 2a58C-1d7aA:
8.2
2a58D-1d7aA:
8.2		 2a58C-1d7aA:
23.50
2a58D-1d7aA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 12 GLY A  71
ALA A  70
ASP A  19
GLY A 122
ILE A 121
 AIR  A 300 (-3.6A)
AIR  A 300 (-3.5A)
AIR  A 300 (-2.6A)
None
None
 1.06A 2b7zA-1d7aA:
undetectable		 2b7zA-1d7aA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 12 GLY A 125
ALA A 126
ILE A  12
GLY A  69
ALA A  21
 None
 0.82A 2nmzB-1d7aA:
undetectable		 2nmzB-1d7aA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		4 / 7 ALA A 127
ALA A 126
ALA A 130
GLN A  24
 None
 0.76A 3a2qA-1d7aA:
0.0		 3a2qA-1d7aA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 9 GLY A  71
ALA A  70
ASP A  19
GLY A 122
ILE A 121
 AIR  A 300 (-3.6A)
AIR  A 300 (-3.5A)
AIR  A 300 (-2.6A)
None
None
 0.92A 3ogpA-1d7aA:
undetectable		 3ogpA-1d7aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 12 GLY A  71
ALA A  70
ASP A  19
GLY A 122
ILE A 121
 AIR  A 300 (-3.6A)
AIR  A 300 (-3.5A)
AIR  A 300 (-2.6A)
None
None
 0.97A 3ogqB-1d7aA:
undetectable		 3ogqB-1d7aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 8 GLY A  71
ALA A  70
ASP A  19
GLY A 122
ILE A 121
 AIR  A 300 (-3.6A)
AIR  A 300 (-3.5A)
AIR  A 300 (-2.6A)
None
None
 1.15A 3so9A-1d7aA:
undetectable		 3so9A-1d7aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 1d7a PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
(Escherichia
coli) 		5 / 12 GLY A  71
ALA A  70
ASP A  19
GLY A 122
ILE A 121
 AIR  A 300 (-3.6A)
AIR  A 300 (-3.5A)
AIR  A 300 (-2.6A)
None
None
 1.02A 3ucbA-1d7aA:
undetectable		 3ucbA-1d7aA:
21.66